Anticoagulants: Pharmacokinetics, Mechanisms of Action, and Indications.

T. Dewald,J. Washam,R. Becker

Published 2018 in Neurosurgery clinics of North America

ABSTRACT

Anticoagulant medications are used widely for a variety of medical and surgical diseases, disorders, and conditions associated with thrombosis and thromboembolism. This review highlights labeled indications, mechanisms of action, potential drug interactions, and specific pharmacokinetic characteristics of available anticoagulants as an essential foundation for guiding selection and management of therapies for patients undergoing neurosurgical procedures.

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