Tumors comprise heterogeneous populations of cells, including immune infiltrates that polarize during growth and metastasis. Our preclinical studies on breast cancer (BCa) identified functional differences in myeloid‐derived suppressor cells based on tumor microenvironment (TME), prompting variations in host immune response to tumor growth, and dissemination based on tissue type.
Location of tumor affects local and distant immune cell type and number
J. Hensel,Vinayak Khattar,Reading Ashton,Carnellia M. Lee,G. Siegal,S. Ponnazhagan
Published 2017 in Immunity, Inflammation and Disease
ABSTRACT
PUBLICATION RECORD
- Publication year
2017
- Venue
Immunity, Inflammation and Disease
- Publication date
2017-02-23
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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