Corneal targeted nanoparticles for sustained natamycin delivery and their PK/PD indices: an approach to reduce dose and dosing frequency.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  International journal of pharmaceutics

• Publication date

  2014-12-30

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1016/j.ijpharm.2014.10.035PMID 25455776
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vitro uptake and release of natamycin Dex-b-PLA nanoparticles from model contact lens materials

  2014cited by this paper
• Dendrimer Nanoparticles for Ocular Drug Delivery

  2013cited by this paper
• Short imidazolium chains effectively clear fungal biofilm in keratitis treatment.

  2013cited by this paper
• Mathematical modeling of drug dissolution.

  2013cited by this paper
• Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies.

  2012cited by this paper
• Bioanalytical method development and validation of natamycin in rabbit tears and its application to ocular pharmacokinetic studies.

  2011cited by this paper
• Diagnostic and Therapeutic Considerations in Fungal Keratitis

  2011cited by this paper
• Biocompatibility of nanostructured chitosan/ poly(vinyl alcohol) blends chemically crosslinked with genipin for biomedical applications.

  2010cited by this paper
• Update on Fungal Keratitis From 1999 to 2008

  2010cited by this paper
• Chitosan coated PLA nanoparticles for ophthalmic delivery: characterization, in-vitro and in-vivo study in rabbit eye.

  2010cited by this paper
• Current efforts and the potential of nanomedicine in treating fungal keratitis

  2010cited by this paper
• Chitosan-based nanostructures: a delivery platform for ocular therapeutics.

  2010cited by this paper
• High pH Tolerance of a Chitosan–PAA Nanosuspension for Ophthalmic Delivery of Pilocarpine

  2010cited by this paper
• Chitosan nanoparticles for drug delivery to the eye

  2009cited by this paper
• Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors.

  2009cited by this paper
• Mucoadhesive polymeric platforms for controlled drug delivery.

  2009cited by this paper
• Contact lens-related microbial keratitis: recent outbreaks

  2008cited by this paper
• Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles.

  2007cited by this paper
• Pharmacodynamic implications for use of antifungal agents.

  2007cited by this paper
• Fungal keratitis in patients with corneal ulcer in Sari, Northern Iran.

  2006cited by this paper
• Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance.

  2006cited by this paper
• Spectrum of fungal keratitis in north China.

  2006cited by this paper
• Fungal Keratitis: Emerging Trends and Treatment Outcomes

  2006cited by this paper
• Spectrum of fungal keratitis in North India.

  2005cited by this paper
• The use of mucoadhesive polymers in ocular drug delivery.

  2005cited by this paper
• Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs.

  2004cited by this paper
• Design of New Formulations for Topical Ocular Administration: Polymeric Nanocapsules Containing Metipranolol

  2004cited by this paper
• Current Perspectives on Ophthalmic Mycoses

  2003cited by this paper
• The Epidemiological Features and Laboratory Results of Fungal Keratitis: A 10-Year Review at a Referral Eye Care Center in South India

  2002cited by this paper
• Design of poly-ε-caprolactone nanospheres coated with bioadhesive hyaluronic acid for ocular delivery

  2002cited by this paper
• Rational dosing of antibiotics: the use of plasma concentrations versus tissue concentrations.

  2002cited by this paper
• Design of poly-epsilon-caprolactone nanospheres coated with bioadhesive hyaluronic acid for ocular delivery.

  2002cited by this paper
• Modeling and comparison of dissolution profiles.

  2001cited by this paper
• Treatment of fungal keratitis by penetrating keratoplasty

  2001cited by this paper
• Treatment of fungal keratitis by penetrating keratoplasty

  2001cited by this paper
• The Draize eye test.

  2001cited by this paper
• What have we learned from pharmacokinetic and pharmacodynamic theories?

  2001cited by this paper
• Spectrum of Fungal Keratitis at Wills Eye Hospital, Philadelphia, Pennsylvania

  2000cited by this paper
• Topical use of chitosan in ophthalmology: tolerance assessment and evaluation of precorneal retention.

  1999cited by this paper
• Selection of Suitable Dispersants for Aqueous Suspensions of Zirconia and Titania Powders using Acoustophoresis

  1999cited by this paper
• Synthesis of a fluorescent chitosan derivative and its application for the study of chitosan-mucin interactions

  1999cited by this paper
• Chitosans as Absorption Enhancers for Poorly Absorbable Drugs 2: Mechanism of Absorption Enhancement

  1997cited by this paper
• The changing spectrum of fungal keratitis in south Florida.

  1994cited by this paper
• Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2)

  1994cited by this paper
• Poly(ε-Caprolactone) Nanocapsules in Carteolol Ophthalmic Delivery

  1993cited by this paper
• Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery.

  1993cited by this paper
• Pharmacologic management of keratomycoses.

  1988cited by this paper
• The fungicidal effect of chitosan on fungi of varying cell wall composition

  1979cited by this paper

• Itraconazole Loaded Micelle Based on Methoxy Poly(Ethylene Glycol)-Poly(D, L-Lactic Acid) for Ocular Drug Delivery: In vitro and in vivo Evaluation

  2025cites this paper
• Progress in Nanotechnology for Treating Ocular Surface Chemical Injuries: Reflecting on Advances in Ophthalmology

  2025cites this paper
• Natamycin Cyclodextrin Supramolecular Complex Loaded Dissolvable Lenses for the Effective Management of Fungal Keratitis

  2025cites this paper
• Nanostructure colloids in ocular drug delivery: advances and challenges

  2025cites this paper
• Comparative Study of Natamycin Encapsulation in Liposomes: Thin-Film vs. Proliposome Methods for Enhanced Stability, Controlled Release, and Efficacy Against Milk Spoilage and Pathogenic Microorganisms

  2025cites this paper
• Nanomedicine in fungal keratitis: current applications and future prospects

  2025cites this paper
• Moderation of cross linkage of sodium alginate-polyethylene oxide films loaded with natamycin for treatment of Aspergillus fumigatus keratitis

  2025cites this paper
• Advances in nanomedicine for retinal drug delivery: overcoming barriers and enhancing therapeutic outcomes

  2024cites this paper
• Nanomicelles empower natamycin in treating fungal keratitis: An in vitro, ex vivo and in vivo study.

  2024cites this paper
• Chitosan/carbomer nanoparticles- laden in situ gel for improved ocular delivery of timolol: in vitro, in vivo, and ex vivo study

  2024cites this paper
• Multifunctional natamycin modified chondroitin sulfate eye drops with anti-inflammatory, antifungal and tissue repair functions possess therapeutic effects on fungal keratitis in mice.

  2024cites this paper
• Review of Potential Drug-Eluting Contact Lens Technologies

  2023cites this paper
• Nano-dimensional in-situ hydrogels of lifitegrast: An advancement in preservation time, sustained release and corneal healing in dry eye syndrome

  2023cites this paper
• Biodegradable Polymer-Based Drug-Delivery Systems for Ocular Diseases

  2023cites this paper
• Preparation of a Sunitinib loaded microemulsion for ocular delivery and evaluation for the treatment of corneal neovascularization in vitro and in vivo

  2023cites this paper
• Natamycin Ocular Delivery: Challenges and Advancements in Ocular Therapeutics

  2023cites this paper
• Chitosan-decorated and tripolyphosphate-crosslinked pH-sensitive niosomal nanogels for Controlled release of fluoropyrimidine 5-fluorouracil.

  2023cites this paper
• Nanomedicine for the Detection and Treatment of Ocular Bacterial Infections

  2023cites this paper
• Recent advances in nanotechnology for the treatment of fungal keratitis

  2023cites this paper
• Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes

  2023cites this paper
• Biopolymers in Mucoadhesive Eye Drops for Treatment of Dry Eye and Allergic Conditions: Application and Perspectives

  2023cites this paper
• Oxidized chondroitin sulfate eye drops ameliorate the prognosis of fungal keratitis with anti-inflammatory and antifungal effects.

  2022cites this paper
• Cyclosporine A Delivery Platform for Veterinary Ophthalmology—A New Concept for Advanced Ophthalmology

  2022cites this paper
• Graph-Based Pharmacokinetic-Pharmadynamic Modeling for Large Scale Systems: Nanoparticles Case

  2022cites this paper
• Generic Purpose Pharmacokinetics-Pharmacodynamics Mathematical Model For Nanomedicine Targeted Drug Delivery: Mouse Model

  2022cites this paper
• Solid lipid nanoparticles and nanostructured lipid carriers: a review of the methods of manufacture and routes of administration

  2022cites this paper
• Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro, and In Vivo Study

  2021cites this paper
• Promising Antifungal Potential of Engineered Non-ionic Surfactant-Based Vesicles: In Vitro and In Vivo Studies

  2021cites this paper
• A dual-functional chitosan derivative platform for fungal keratitis.

  2021cites this paper
• Nanocarrier drugs for eye treatment

  2021cites this paper
• Pharmacokinetic and pharmacodynamic evaluation of gemifloxacin chitosan nanoparticles as an antibacterial ocular dosage form.

  2021cites this paper
• Antimicrobial nanomedicine for ocular bacterial and fungal infection

  2021cites this paper
• Current applications and prospects of nanoparticles for antifungal drug delivery

  2021cites this paper
• Topical corneal targeted sustained release amphotericin B liposomal formulation for the treatment of fungal keratitis and its PK-PD evaluation

  2020cites this paper
• RETRACTED ARTICLE: Bimatoprost Imprinted Silicone Contact Lens to Treat Glaucoma

  2020cites this paper
• Reduced administration frequency for the treatment of fungal keratitis: a sustained natamycin release from a micellar solution

  2020cites this paper
• Voriconazole-loaded self-nanoemulsifying drug delivery system (SNEDDS) to improve transcorneal permeability

  2020cites this paper
• Timolol loaded microemulsion laden silicone contact lens to manage glaucoma: in vitro and in vivo studies

  2020cites this paper
• Ocular delivery of natamycin based on monoolein/span 80/poloxamer 407 nanocarriers for the effectual treatment of fungal keratitis

  2020influential citation
• Niosomes: Do They Increase the Potency of Topical Natamycin Ketorolac Formula in Treating Aspergillus Keratitis? An Experimental Study

  2020cites this paper
• Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization.

  2020cites this paper
• Efficiency of nanoparticles for treatment of ocular infections: Systematic literature review

  2020cites this paper
• Natamycin-loaded electrospun poly(ε-caprolactone) nanofibers as an innovative platform for antifungal applications

  2020cites this paper
• Promising bioadhesive ofloxacin-loaded polymeric nanoparticles for the treatment of ocular inflammation: formulation and in vivo evaluation

  2020cites this paper
• Effect of Drugs and Nanoformulation on Ocular Cells in Various Disease States

  2020cites this paper
• Recent Advances in Nano-Formulations for Ophthalmic Drug Delivery

  2020cites this paper
• Subconjunctival dendrimer-drug therapy for the treatment of dry eyein rabbits with induced autoimmune dacryoadenitis

  2020cites this paper
• Natamycin-loaded electrospun poly(ε-caprolactone) nanofibers as an innovative platform for antifungal applications

  2020cites this paper
• Suvremeni farmaceutski oblici za topikalno liječenje glaukoma

  2019cites this paper
• Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation

  2019cites this paper
• Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of Natamycin

  2019cites this paper
• Development of polysaccharide-based mucoadhesive ophthalmic lubricating vehicles: The effect of different polymers on physicochemical properties and functionality

  2019cites this paper
• Pharmacologic therapy of mycotic keratitis.

  2019cites this paper
• Natamycin niosomes as a promising ocular nanosized delivery system with ketorolac tromethamine for dual effects for treatment of candida rabbit keratitis; in vitro/in vivo and histopathological studies

  2019cites this paper
• Polyene Macrolide Antibotic Derivatives: Preparation, Overcoming Drug Resistance, and Prospects for Use in Medical Practice (Review)

  2019cites this paper
• The Efficiency of Cyclosporine A-Eluting Contact Lenses for the Treatment of Dry Eye

  2019cites this paper
• Challenges in the Polyene- and Azole-Based Pharmacotherapy of Ocular Fungal Infections

  2019cites this paper
• Formulation Development, Optimization, and In Vitro-In Vivo Characterization of Natamycin-Loaded PEGylated Nano-Lipid Carriers for Ocular Applications.

  2018cites this paper
• Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma

  2018influential citation
• Subconjunctival dendrimer-drug therapy for the treatment of dry eye in a rabbit model of induced autoimmune dacryoadenitis.

  2018cites this paper
• Recent advances in topical nano drug-delivery systems for the anterior ocular segment.

  2018cites this paper
• Status of Research in the Field of Chemetherapy for Infectious Diseases in the last 5 Years

  2018cites this paper
• Current perspectives on natamycin in ocular fungal infections

  2017cites this paper
• Nanoparticulate fingolimod delivery system based on biodegradable poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): design, optimization, characterization and in-vitro evaluation

  2017cites this paper
• Review: Emerging strategies for antimicrobial drug delivery to the ocular surface: Implications for infectious keratitis.

  2017cites this paper
• Nanoparticles for drug delivery to the anterior segment of the eye.

  2017cites this paper
• Micelle carriers based on macrogol 15 hydroxystearate for ocular delivery of terbinafine hydrochloride: In vitro characterization and in vivo permeation

  2017cites this paper
• Challenges of corneal infections

  2016cites this paper
• A review on therapeutic contact lenses for ocular drug delivery

  2016cites this paper
• In vitro and in vivo evaluation of novel implantation technology in hydrogel contact lenses for controlled drug delivery.

  2016cites this paper
• Update on fungal keratitis

  2016cites this paper
• Challenges Associated with the Quantification of Tear Fluids

  2016cites this paper
• Extended release of ketotifen from silica shell nanoparticle-laden hydrogel contact lenses: in vitro and in vivo evaluation

  2016cites this paper
• Antifungal nanomaterials: Synthesis, properties, and applications

  2016cites this paper
• Preparation and in vivo evaluation of in situ gel system as dual thermo-/pH-responsive nanocarriers for sustained ocular drug delivery

  2015cites this paper
• Multidimensional Ophthalmic Nanosystems for Molecular Detection and Therapy of Eye Disorders.

  2015cites this paper