Reinforcement learning, the process by which an organism flexibly adapts behavior in response to reward and punishment, is vital for the proper execution of everyday behaviors, and its dysfunction has been implicated in a wide variety of mental disorders. Here, we use computational trial-by-trial analysis of data of female rats performing a probabilistic reward learning task and demonstrate that core computational processes underlying value-based decision making fluctuate across the estrous cycle, providing a neuroendocrine substrate by which gonadal hormones may influence adaptive behavior.
Reinforcement learning across the rat estrous cycle.
J. Verharen,J. Kentrop,L. Vanderschuren,R. Adan
Published 2019 in Psychoneuroendocrinology
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
Psychoneuroendocrinology
- Publication date
2019-02-01
- Fields of study
Biology, Medicine, Psychology
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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