Oxytocin Receptor Gene (OXTR) and Deviant Peer Affiliation: A Gene–Environment Interaction in Adolescent Antisocial Behavior

Although the oxytocin receptor gene (OXTR) is involved in aggression and social affiliation, it has not been examined in gene-environment interaction studies. This longitudinal study examined the effect of genetic variants in OXTR and its gene-environment interaction with perceived deviant peer affiliation in the trajectories of antisocial behavior in 323 adolescents (182 males) from 13 to 18 years. Annual assessments of reactive and proactive aggression, delinquency, and friends’ delinquency, as well as DNA at age 17 were collected. Gene-based tests yielded no main effect of OXTR, but revealed a significant gene-environment interaction in proactive aggression and delinquency. Variation in the OXTR might affect the influence of deviant peer affiliation on antisocial behavior, contributing to a better understanding of individual differences in antisocial behavior.

• Publication year

  2018

• Venue

  Journal of Youth and Adolescence

• Publication date

  2018-10-12

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1007/s10964-018-0939-xPMID 30315439
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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