serum YKL-40 Levels in patients with esophageal

Aims and background: YKL-40 is a glycoprotein secreted by macrophages, neutrophils and malignant tumor cells. YKL-40 is expressed and secreted by several types of tumors. The aim of this study examined the clinical usefulness of YKL-40 for detection in esophageal squamous cell carcinoma (ESCC). Methods: Using ELISA kits, we measured the concentration of YKL-40 in serum from 100 patients with ESCC and compared this concentration with healthy population. Results: We found significantly higher serum levels of YKL-40 in patients with ESCC compared to the healthy population (P , 0.0001). Conclusions: These results suggested that regarding serum YKL-40 as a tumor marker could be benefical in the early clinical diagnosis.

• Publication year

  2011

• Venue

  Unknown venue

• Publication date

  2011-04-04

• Fields of study

  Medicine

• Identifiers
  DOI 10.4137/CGM.S7046
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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