A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2 signalling pathways

Xiao Jiang,Fan Wu,Yuan Xu,Jianxin Yan,Yin-Di Wu,Sheng-Hong Li,Xuan Liao,Jun-Xian Liang,Ze-Hua Li,Hong-Wei Liu

Published 2019 in Experimental Dermatology

ABSTRACT

Recent evidence suggests that angiotensin II (Ang II) plays a role in cutaneous wound healing. Mesenchymal stem cells (MSCs) are known as a rich source of cells that re‐establish healed skin. However, the potential impact of Ang II on MSC differentiation into keratinocytes is still unknown.

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