Evaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum C.DC in rodents.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Ethnopharmacology

• Publication date

  2012-06-26

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.jep.2012.05.016PMID 22588049
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Involvement of the L-arginine-nitric oxide pathway in the antinociception caused by fruits of Prosopis strombulifera (Lam.) Benth.

  2012cited by this paper
• Changes in the vascular cell adhesion molecule-1, intercellular adhesion molecule-1 and c-reactive protein following administration of aqueous extract of piper sarmentosum on experimental rabbits fed with cholesterol diet

  2011cited by this paper
• Studies on antidepressant and antinociceptive effects of ethyl acetate extract from Piper laetispicum and structure-activity relationship of its amide alkaloids.

  2011cited by this paper
• Different responses to oxidized low-density lipoproteins in human polarized macrophages

  2011cited by this paper
• Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.

  2011cited by this paper
• Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume

  2011cited by this paper
• In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni

  2011cited by this paper
• A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum.

  2011cited by this paper
• Antioxidant Capacity and Larvicidal and Antifungal Activities of Essential Oils and Extracts from Piper krukoffii

  2011cited by this paper
• The effect of Piper aduncum Linn. (Family: Piperaceae) essential oil as aerosol spray against Aedes aegypti (L.) and Aedes albopictus Skuse.

  2011cited by this paper
• Chemistry and Biological Activity of Essential Oils from Piper Claussenianum (Piperaceae)

  2010cited by this paper
• Essential Oil Composition, Antioxidant Capacity and Antifungal Activity of Piper divaricatum

  2010cited by this paper
• Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritum.

  2010cited by this paper
• Antiulcerogenic activity of hydroalcoholic extract of Achillea millefolium L.: involvement of the antioxidant system.

  2010cited by this paper
• In vivo anti-nociceptive and anti-inflammatory activities of the aqueous extract of the leaves of Piper sarmentosum.

  2010cited by this paper
• Anti-secretory, anti-inflammatory and anti-Helicobacter pylori activities of several fractions isolated from Piper carpunya Ruiz & Pav.

  2010cited by this paper
• In Vitro Investigation of the Potential Immunomodulatory and Anti-Cancer Activities of Black Pepper (Piper nigrum) and Cardamom (Elettaria cardamomum)

  2010influential reference
• Anti-inflammatory, anti-nociceptive and antipyretic effects of the ethanol extract from root of Piper sarmentosum Roxb.

  2010cited by this paper
• Laetispicine, an amide alkaloid from Piper laetispicum, presents antidepressant and antinociceptive effects in mice.

  2009cited by this paper
• Antinociceptive effect of crude extract, fractions and three alkaloids obtained from fruits of Piper tuberculatum.

  2009cited by this paper
• In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species

  2008cited by this paper
• Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice.

  2008cited by this paper
• Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself?

  2008cited by this paper
• Anti-inflammatory activity of the extract, fractions and amides from the leaves of Piper ovatum Vahl (Piperaceae).

  2008influential reference
• Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation

  2008cited by this paper
• In vitro antifungal activity of extracts and neolignans from Piper regnellii against dermatophytes.

  2008influential reference
• Piper longum Linn. Extract inhibits TNF-alpha-induced expression of cell adhesion molecules by inhibiting NF-kappaB activation and microsomal lipid peroxidation.

  2008cited by this paper
• Flavonoid-rich fraction of Maytenus ilicifolia Mart. ex. Reiss protects the gastric mucosa of rodents through inhibition of both H+,K+ -ATPase activity and formation of nitric oxide.

  2007cited by this paper
• An ethanol extract of Piper betle Linn. mediates its anti‐inflammatory activity via down‐regulation of nitric oxide

  2007cited by this paper
• Antifungal amides from Piper scutifolium and Piper hoffmanseggianum.

  2007cited by this paper
• Essential Oils of Piper dumosum Rudge and Piper aleyreanum C.DC (Piperaceae) from Brazilian Amazonian Forest

  2007cited by this paper
• Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.

  2007cited by this paper
• Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.

  2007influential reference
• In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.

  2006influential reference
• Twenty-five years of research on medicinal plants in Latin America: a personal view.

  2005cited by this paper
• New Amides and Gastroprotective Constituents from the Fruit of Piper chaba

  2004influential reference
• Immunomodulatory and antitumor activity of Piper longum Linn. and piperine.

  2004cited by this paper
• Mechanisms of the inflammatory response.

  2004cited by this paper
• Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules.

  2004cited by this paper
• Piperaceae do Nordeste brasileiro I: estado do Ceará

  2004cited by this paper
• Constituents of Piper aleyreanum (Piperaceae)

  2003cited by this paper
• Anti-inflammatory properties of piperlactam S: modulation of complement 5a-induced chemotaxis and inflammatory cytokines production in macrophages.

  2003cited by this paper
• Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB).

  2003cited by this paper
• Animal models in gastrointestinal alcohol research-a short appraisal of the different models and their results.

  2003cited by this paper
• Gastroduodenal mucosal defense: an integrated protective response.

  2003cited by this paper
• Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus.

  2002cited by this paper
• Gastroduodenal mucosal defense: an integrated protective response

  2002cited by this paper
• Anti-inflammatory lipid mediators and insights into the resolution of inflammation

  2002cited by this paper
• Antioxidant properties of natural compounds used in popular medicine for gastric ulcers.

  2002cited by this paper
• Essential oil analysis of 10 Piperaceae species from the Brazilian Atlantic forest.

  2001influential reference
• Biological activity of plant extracts: novel analgesic drugs

  2001cited by this paper
• Molecular mechanisms of nociception

  2001cited by this paper
• Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara.

  2000cited by this paper
• NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.

  2000cited by this paper
• Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs

  2000cited by this paper
• Antifungal amides from Piper hispidum and Piper tuberculatum.

  2000influential reference
• Distribution and regulation of cyclooxygenase‐2 in carrageenan‐induced inflammation

  1999influential reference
• Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action.

  1999cited by this paper
• Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice

  1998cited by this paper
• Recent natural products based drug development: a pharmaceutical industry perspective.

  1998cited by this paper
• Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice.

  1997cited by this paper
• Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy.

  1997influential reference
• Phytochemistry of the genus Piper

  1997cited by this paper
• Anti‐inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy

  1996influential reference
• Antioedematogenic and antinociceptive actions of NPC 18521, a novel bradykinin B2 receptor antagonist.

  1996cited by this paper
• Cyclo‐oxygenase and nitric oxide synthase isoforms in rat carrageenin‐induced pleurisy

  1994cited by this paper
• The formalin test: an evaluation of the method

  1992cited by this paper
• Endothelin‐1 inhibits PAF‐induced paw oedema and pleurisy in the mouse

  1992influential reference
• Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.

  1992cited by this paper
• The Plant Book

  1988cited by this paper
• The plant book : a portable dictionary of the higher plants

  1988cited by this paper
• The formalin test in mice: dissociation between inflammatory and non‐inflammatory pain

  1987cited by this paper
• Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury.

  1979cited by this paper
• Proceedings: A method for the quantitative estimation of gastric barrier mucus.

  1974influential reference
• Proceedings: A method for the quantitative estimation of gastric barrier mucus.

  1974cited by this paper
• Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent.

  1968influential reference
• A GENERALIZATION OF THE RETENTION INDEX SYSTEM INCLUDING LINEAR TEMPERATURE PROGRAMMED GAS-LIQUID PARTITION CHROMATOGRAPHY.

  1963cited by this paper

• Nature's Pain Relievers: Unveiling the Power of Plant Extracts Against Non-Steroidal Antiinflammatory Drugs

  2025cites this paper
• Linalool and trans-nerolidol prevent pentylenetetrazole-induced seizures in adult zebrafish

  2025cites this paper
• Verbenone prevents cyclophosphamide-induced oxidative stress, inflammation, fibrosis, and cellular changes in the kidneys of Swiss albino mice by targeting NF-ĸB/TGF-β signaling pathways

  2025cites this paper
• Cytotoxic Activity and Phytochemical Analysis of Artemisia biennis Essential Oils at Different Growth Stages

  2024cites this paper
• Essential Oils from the Genus Piper Promote Antinociception by Modulating TRP Channels and Anti‐Inflammatory Effects in Adult Zebrafish

  2024cites this paper
• Chemical Composition, Analgesic and Anti-Inflammatory Activity of Pelargonium peltatum Essential Oils from Eastern Cape, South Africa

  2023cites this paper
• Analgesic and Anti-inflammatory Potential of Ricinus communis Linn.: Evidence from Pharmacology to Clinical Studies

  2023cites this paper
• The importance and use of Amaranthus for crop diversification in the SADC region

  2023cites this paper
• Preparation and Characterization of Blank and Nerolidol-Loaded Chitosan–Alginate Nanoparticles

  2022cites this paper
• In vitro screening and in vivo evaluation of antiparasitic phytochemicals against Cryptocaryon irritans in pompano, Trachinotus ovatus

  2022cites this paper
• Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats

  2022cites this paper
• Metal–organic framework on porous TiO2 thin film-coated alumina beads for fractional distillation of plant essential oils

  2022cites this paper
• Anti-Inflammatory Effects of Campomanesia xanthocarpa Seed Extract Obtained from Supercritical CO2

  2021cites this paper
• Analgesic Potential of Terpenes Derived from Cannabis sativa

  2021cites this paper
• Anti-Vpr activities of sesqui- and diterpenoids from the roots and rhizomes of Kaempferia candida

  2021cites this paper
• Nerolidol, a Sesquiterpene Alcohol, Attenuates Acute Myocardial Infarction in Rats

  2021cites this paper
• Chemical composition and biological activities of essential oils of Piper species from the Amazon

  2021cites this paper
• Toward the use of nanotechnology to enhance the therapeutic effect of nerolidol

  2021cites this paper
• Protective effect of nerolidol on lipopolysaccharide-induced acute lung injury through the inhibition of NF-κB activation by the reduction of p38 MAPK and JNK phosphorylation

  2020cites this paper
• Systematic review: Medicinal use and scientific elucidation of the Piper genus for the treatment of symptoms and inflammatory diseases

  2020cites this paper
• Cannabidiol and tetrahydrocannabinol concentrations in commercially available CBD E-liquids in Switzerland.

  2020cites this paper
• Metabolism and Pharmacokinetics of SP-8356, a Novel (1S)-(−)-Verbenone Derivative, in Rats and Dogs and Its Implications in Humans

  2020cites this paper
• Avaliação da toxicidade in silico do monoterpeno Verbenona

  2020cites this paper
• Anti-inflammatory and antinociceptive activities of a phenylpropanoid-enriched fraction of Duguetia furfuracea

  2020cites this paper
• ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF MONOTERPENOID MYRTENAL IN RODENTS

  2019cites this paper
• Anti-inflammatory and central and peripheral anti-nociceptive activities of α-asarone through the inhibition of TNF-α production, leukocyte recruitment and iNOS expression, and participation of the adenosinergic and opioidergic systems

  2019cites this paper
• Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy

  2019cites this paper
• Galangin Prevents Increased Susceptibility to Pentylenetetrazol-Stimulated Seizures by Prostaglandin E2.

  2019cites this paper
• Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

  2019cites this paper
• Chemical composition and evaluation of the anti-inflammatory and antinociceptive activities of Duguetia furfuracea essential oil: Effect on edema, leukocyte recruitment, tumor necrosis factor alpha production, iNOS expression, and adenosinergic and opioidergic systems.

  2019cites this paper
• Chemical Composition and Role of Opioidergic System in Antinociceptive Effect of Ziziphora Clinopodioides Essential Oil

  2018cites this paper
• Gastroprotective effects of methanol extract of Eremomastax speciosa leaf harvested in Southern part of Nigeria in rat

  2018cites this paper
• Comparison of the Chemical Composition of the Essential Oils from the Fresh and Dried Leaves of Greenwayodendron Suaveolens (Engl. & Diels)

  2018cites this paper
• Volatile oil production, proline, protein and DNA profile in three medicinal plants exposed to short-term drought stress

  2018cites this paper
• Role of L-arginine/NO/cGMP/KATP channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats

  2018cites this paper
• Effect of microencapsulated essential oil form Chamaecyparis obtusa on monocyte-derived dendritic cell activation and CD4+ T cell polarization

  2018cites this paper
• Phytochemical screening and assessment of analgesic, Anti-inflammatory and hematological properties of the fruit of Berberis baluchistanica.

  2017cites this paper
• Chemical characterization, toxicology and mechanism of gastric antiulcer action of essential oil from Gallesia integrifolia (Spreng.) Harms in the in vitro and in vivo experimental models.

  2017cites this paper
• Toxicological studies and assessment of pharmacological activities of Abrus precatorius L . ( Fabaceae ) ethanolic leaves extract in the management of pain , psychiatric and neurological conditions : An in-vivo study

  2017cites this paper
• Anti-Inflammatory Effects of Chamaecyparis Obtusa Essential Oil on Peripheral Blood Mononuclear Cells

  2017cites this paper
• Anti-inflammatory and Anti-nociceptive Activities of African Medicinal Spices and Vegetables

  2017cites this paper
• Analgesic, Anti-Inflammatory, and Antioxidant Activities of Byrsonima duckeana W. R. Anderson (Malpighiaceae)

  2017cites this paper
• Anticonvulsive activity of (1S)-(−)-verbenone involving RNA expression of BDNF, COX-2, and c-fos

  2017cites this paper
• Essential Oils from Neotropical Piper Species and Their Biological Activities

  2017influential citation
• Anti-inflammatory and toxicological evaluation of essential oil from Piper glabratum leaves.

  2017cites this paper
• Evaluation of Analgesic Properties of Piper Nigrum Essential Oil: a Randomized, Double-blind, Placebo-controlled Study

  2016cites this paper
• HERBAL TREATMENT ALTERNATIVES FOR PEPTIC ULCER DISEASE

  2016cites this paper
• Assessment of antinociceptive, antipyretic and antimicrobial activity of Piper cubeba L. essential oil in animal models.

  2016cites this paper
• Nerolidol exhibits antinociceptive and anti‐inflammatory activity: involvement of the GABAergic system and proinflammatory cytokines

  2016cites this paper
• ANTIULCEROGENIC BENEFITS OF HERBAL INGREDIENTS IN ETHANOL-INDUCED ANIMAL MODELS

  2016cites this paper
• Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities

  2016cites this paper
• Toxicological analysis and anti-inflammatory effects of essential oil from Piper vicosanum leaves.

  2015cites this paper
• Biological Activities of Essential Oils

  2015cites this paper
• REVIEW ON ANTIULCEROGENIC ACTIVITY OF MUSA SAPIENTUM ON EXPERIMENTAL PEPTIC ULCERS IN RATS

  2015cites this paper
• Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity

  2015cites this paper
• Evaluación de la actividad repelente de aceites esenciales de plantas Piperáceas del departamento de Chocó, Colombia

  2015cites this paper
• Analgesic Potential of Essential Oils

  2015influential citation
• Copaifera langsdorffii: evaluation of potential gastroprotective of extract and isolated compounds obtained from leaves

  2015cites this paper
• Chemical Composition, Antioxidant, Antimicrobial and Anti-inflammatory Activities of the Stem and Leaf Essential Oils from Piper flaviflorum from Xishuangbanna, SW China

  2014cites this paper
• Anti-Inflammatory and Antinociceptive Effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in Rodents

  2014cites this paper
• In vitro metabolism of the alkaloid piplartine by rat liver microsomes.

  2014cites this paper
• Antinociceptive and Anti-edematous Activities of the Essential Oils of Two Balkan EndemicLaserpitium Species

  2014cites this paper
• Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract

  2014cites this paper
• POTENT ULCER PROTECTIVE ACTION OF ANTI- INFLAMMATORY HERBS: A SHORT REVIEW

  2014cites this paper
• ssential oils of Amazon Piper species and their cytotoxic , antifungal , ntioxidant and anti-cholinesterase activities oyce

  2014cites this paper
• Importance of a multidisciplinary evaluation of Piper genus for development of new natural products in Latin America

  2014cites this paper
• Essential oils of Amazon Piper species and their cytotoxic, antifungal, antioxidant and anti-cholinesterase activities

  2014cites this paper
• Endogenous opiates and behavior: 2012.

  2013cites this paper
• Antiulcer and gastric antisecretory effects of dichloromethane fraction and piplartine obtained from fruits of Piper tuberculatum Jacq. in rats.

  2013cites this paper
• Compilation of toxicological data of major volatile essential oil components

  2013cites this paper
• ANÁLISE NUTRICIONAL E ATIVIDADE ANTINOCICEPTIVA DO ÓLEO PLUKENETIA POLYADENIA.

  2013cites this paper
• Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric.

  2013cites this paper
• Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats.

  2013cites this paper
• Atividade antinociceptiva do óleo essencial de Echinodorus macrophyllus(Kunth.) Micheli (Alismataceae)

  2012cites this paper