Increased killer immunoglobulin‐like receptor expression and functional defects in natural killer cells in lung cancer

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Immunology

• Publication date

  2011-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-2567.2011.03415.xPMID 21342183PMCID PMC3088971
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Immunotherapy for lung cancer.

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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1979cited by this paper
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  1979cited by this paper

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  2013cites this paper
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