Modification of bone repair hydroxyapatite scaffold by hydrothermal method with assistance of copperions: Testing the angiogenesis using Chick Chorioallantoic Membrane as ex vivo model

The angiogenesis in the surface of hydroxyapatite scaffolds materials for bone repair was studied by establishing Chick Chorioallantoic Membrane model. Chick Chorioallantoic Membrane model with heavy vascularization was prepared to explore the angiogenesis formations. Hydroxyapatite scaffold has been coated hydrothermally with assistance of copper ions to improve its properties. The morphology of the new product was changed to the flower-like shape (micro/nano-structure) compared with uncoated scaffold. The optical camera, optical microscopic and scanning electron microscope were used to charcterized the investigated results. The investigated results implied that the modified (coated) scaffold can promoted angiogenesis formations compared with the uncoated scaffold. Furthermore, the present tests with chicken chorioallantoic membrane model allow a convenient, efficient, and low-cost method of exploring the angiogenesis on scaffolds surfaces.

• Publication year

  2018

• Venue

  2018 International Conference on Computer, Control, Electrical, and Electronics Engineering (ICCCEEE)

• Publication date

  2018-08-01

• Fields of study

  Medicine, Materials Science, Chemistry, Engineering

• Identifiers
  DOI 10.1109/ICCCEEE.2018.8515824
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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