cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cellular Signalling

• Publication date

  2008-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.cellsig.2008.03.009PMID 18450420PMCID PMC2477739
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A-kinase anchoring proteins take shape.

  2007cited by this paper
• Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.

  2007cited by this paper
• Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme

  2007cited by this paper
• Cyclic GMP-dependent Protein Kinase Iα Inhibits Thrombin Receptor-mediated Calcium Mobilization in Vascular Smooth Muscle Cells*

  2006cited by this paper
• Role of cyclic GMP in gene regulation.

  2005cited by this paper
• Identification of the Interface between cGMP-dependent Protein Kinase Iβ and Its Interaction Partners TFII-I and IRAG Reveals a Common Interaction Motif*

  2005cited by this paper
• Function of cGMP-dependent Protein Kinases in the Nervous System

  2005cited by this paper
• Formin Homology Domain Protein (FHOD1) Is a Cyclic GMP-dependent Protein Kinase I-binding Protein and Substrate in Vascular Smooth Muscle Cells*

  2004cited by this paper
• Distribution of IRAG and cGKI‐isoforms in murine tissues

  2004cited by this paper
• Nitric oxide regulates c-fos expression in nucleus tractus solitarii induced by baroreceptor activation via cGMP-dependent protein kinase and cAMP response element-binding protein phosphorylation.

  2004cited by this paper
• IRAG is essential for relaxation of receptor‐triggered smooth muscle contraction by cGMP kinase

  2004cited by this paper
• Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

  2003cited by this paper
• Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected].

  2003cited by this paper
• Association of phospholamban with a cGMP kinase signaling complex.

  2003cited by this paper
• Physiology and Pathophysiology of Vascular Signaling Controlled by Cyclic Guanosine 3′,5′-Cyclic Monophosphate–Dependent Protein Kinase

  2003cited by this paper
• cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I*

  2002cited by this paper
• Downloaded from http://circres.ahajournals.org / by guest on February 21, 2013Functional Reconstitution of Vascular Smooth Muscle Cells With cGMP-Dependent Protein Kinase I Isoforms

  2002cited by this paper
• Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta.

  2001cited by this paper
• Transcriptional regulation by the phosphorylation-dependent factor CREB

  2001cited by this paper
• Functional Analysis of Type 1α cGMP-dependent Protein Kinase Using Green Fluorescent Fusion Proteins*

  2001cited by this paper
• Molecular Determinants of the Interaction between the Inositol 1,4,5-Trisphosphate Receptor-associated cGMP Kinase Substrate (IRAG) and cGMP Kinase Iβ* 210

  2001cited by this paper
• NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation

  2000cited by this paper
• Cysteine-rich Protein 2, a Novel Substrate for cGMP Kinase I in Enteric Neurons and Intestinal Smooth Muscle*

  2000cited by this paper
• Fos expression is induced by increased nitric oxide release in rat spinal cord dorsal horn.

  2000cited by this paper
• Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ

  2000cited by this paper
• Cyclic AMP- and Cyclic GMP-dependent Protein Kinases Differ in Their Regulation of Cyclic AMP Response Element-dependent Gene Transcription*

  1999cited by this paper
• Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP‐dependent protein kinase

  1999cited by this paper
• AKAPs: from structure to function.

  1999cited by this paper
• Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action.

  1999cited by this paper
• Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha.

  1999cited by this paper
• Effect of nitric oxide synthesis inhibition on c-Fos expression in hippocampus and cerebral cortex following two forms of learning in rats: an immunohistochemistry study.

  1999cited by this paper
• Phosphorylation of splicing factor SF1 on Ser20 by cGMP‐dependent protein kinase regulates spliceosome assembly

  1999cited by this paper
• A Novel Interaction of cGMP-dependent Protein Kinase I with Troponin T*

  1999cited by this paper
• Regulation of gene expression by cyclic GMP-dependent protein kinase requires nuclear translocation of the kinase: identification of a nuclear localization signal

  1997cited by this paper
• Membrane Localization of cAMP-dependent Protein Kinase Amplifies cAMP Signaling to the Nucleus in PC12 Cells*

  1996cited by this paper
• Regulation of Gene Expression by cGMP-dependent Protein Kinase

  1996cited by this paper
• Nitric oxide and cGMP analogs activate transcription from AP‐1‐responsive promoters in mammalian cells

  1995cited by this paper
• High-affinity binding and localization of the cyclic GMP-dependent protein kinase with the intermediate filament protein vimentin.

  1994cited by this paper
• Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells

  1993cited by this paper
• Vimentin is transiently co-localized with and phosphorylated by cyclic GMP-dependent protein kinase in formyl-peptide-stimulated neutrophils.

  1991cited by this paper
• highlighted topics Signal Transduction in Smooth Muscle Invited Review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression

  year unknowncited by this paper

• The photoreceptor protective cGMP‐analog Rp‐8‐Br‐PET‐cGMPS interacts with cGMP‐interactors PKGI, PDE1, PDE6, and PKAI in the degenerating mouse retina

  2023cites this paper
• Novel Functional Features of cGMP Substrate Proteins IRAG1 and IRAG2

  2023cites this paper
• The Interplay between cGMP and Calcium Signaling in Alzheimer’s Disease

  2022cites this paper
• IL-1β dysregulates cGMP signaling in the newborn lung.

  2020cites this paper
• Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines

  2019cites this paper
• Transforming growth factor-β downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling.

  2019cites this paper
• Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion

  2018cites this paper
• Cyclic Nucleotide-Directed Protein Kinases in Cardiovascular Inflammation and Growth

  2018cites this paper
• S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling

  2018cites this paper
• The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43

  2017cites this paper
• Regulatory role of nitric oxide in plants

  2015cites this paper
• The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis.

  2015cites this paper
• cGMP-dependent protein kinase I gamma encodes a nuclear localization signal that regulates nuclear compartmentation and function.

  2014cites this paper
• Exposure of cardiac microvascular endothelial cells to harmful stimuli : a study of the cellular responses and mechanisms

  2014cites this paper
• Series : Cancer and Metabolism GUCY 2 C : at the intersection of obesity and cancer

  2013cites this paper
• Protein kinase G type I in cardiac myocytes: unmasked at last?

  2013cites this paper
• cGMP-dependent protein kinase I&bgr; regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon

  2013cites this paper
• GUCY2C: at the intersection of obesity and cancer.

  2013cites this paper
• Proprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport.

  2013cites this paper
• Heterogeneous nuclear ribonucleoprotein A1 is a novel cellular target of atrial natriuretic peptide signaling in renal epithelial cells.

  2012cites this paper
• Endothelial control of vasomotor tone: the kidney perspective.

  2012cites this paper
• IRAG and novel PKG targeting in the cardiovascular system.

  2011cites this paper
• Implication of microRNAs in atrial natriuretic peptide and nitric oxide signaling in vascular smooth muscle cells.

  2011cites this paper
• Nitric oxide signaling: classical, less classical, and nonclassical mechanisms.

  2011cites this paper
• PKGIα inhibits the proliferation of cerebral arterial smooth muscle cell induced by oxyhemoglobin after subarachnoid hemorrhage.

  2011cites this paper
• Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction.

  2011cites this paper
• Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle

  2011cites this paper
• Regulation of bone turnover by calcium‐regulated calcium channels

  2010cites this paper
• cGMP-dependent protein kinase type I promotes CREB/CRE-mediated gene expression in neurons of the lateral amygdala.

  2010cites this paper
• Functional osteoclast attachment requires inositol-1,4,5-trisphosphate receptor-associated cGMP-dependent kinase substrate

  2010influential citation
• IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.

  2010influential citation
• cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action

  2010cites this paper
• Two decades of new concepts in nitric oxide signaling: From the discovery of a gas messenger to the mediation of nonenzymatic posttranslational modifications

  2009cites this paper
• Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO* and beyond.

  2009cites this paper
• Rolle der cGMP-abhängigen Proteinkinase Typ I für das Angstgedächtnis und die synaptische Plastizität in der lateralen Amygdala

  2009cites this paper
• Inositol 1,4,5-triphosphate-associated cGMP kinase substrate: Basis Sequence: Mouse.

  2008cites this paper
• Change in the subcellular localization of MI-ER1α is associated with breast cancer progression

  2008cites this paper