Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis

L. Amezcua,Ashley H Beecham,S. Delgado,Á. Chinea,M. Burnett,C. Manrique,R. Gomez,M. Comabella,X. Montalban,M. Ortega,Leticia Tornes,B. Lund,T. Islam,D. Conti,J. Oksenberg,J. McCauley

Published 2018 in Annals of Clinical and Translational Neurology

ABSTRACT

Hispanics with multiple sclerosis (MS) present younger and more often with optic neuritis (ON) as compared to Whites in the western United States. Regional differences related to Hispanic genetic admixture could be responsible. We investigated the association between global genetic ancestry and ON and age at onset of MS in Hispanics.

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