Development and validation of a sensitive UHPLC-MS/MS method for quantitation of prucalopride in rat plasma and its application to pharmacokinetics study.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

• Publication date

  2016-10-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jchromb.2016.09.006PMID 27614256
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Selective separation and characterisation of stress degradation products and process impurities of prucalopride succinate by LC-QTOF-MS/MS.

  2016cited by this paper
• Constipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation

  2014cited by this paper
• Systematic review with meta‐analysis: highly selective 5‐HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation

  2014cited by this paper
• Effect of Prucalopride on the Pharmacokinetics of Oral Contraceptives in Healthy Women

  2013cited by this paper
• Sex dependent pharmacokinetics, tissue distribution and excretion of peimine and peiminine in rats assessed by liquid chromatography-tandem mass spectrometry.

  2013cited by this paper
• Oral bioavailability and gender-related pharmacokinetics of celastrol following administration of pure celastrol and its related tablets in rats.

  2012cited by this paper
• Effect of renal impairment on the pharmacokinetics of prucalopride: a single- dose open-label Phase I study

  2012cited by this paper
• New-generation 5-HT4 receptor agonists: potential for treatment of gastrointestinal motility disorders

  2010cited by this paper
• Safety assessment of prucalopride in elderly patients with constipation: a double‐blind, placebo‐controlled study

  2009cited by this paper
• Survey of laxative use by adults with self‐defined constipation in South America and Asia: a comparison of six countries

  2009cited by this paper
• A multinational survey of prevalence and patterns of laxative use among adults with self‐defined constipation

  2008cited by this paper
• A placebo-controlled trial of prucalopride for severe chronic constipation.

  2008cited by this paper
• Gender Differences in the Oral Pharmacokinetics of Fluconazole

  2007cited by this paper
• Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction

  2006cited by this paper
• Current concepts: Chronic constipation

  2003cited by this paper
• An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking

  2001cited by this paper
• Bioanalytical Method Validation—A Revisit with a Decade of Progress

  2000cited by this paper

• Fabrication of promising competitive graphene nanocomposite transducer to determine Prucalopride succinate in pharmaceutical formulation and in spiked human biological fluids

  2025cites this paper
• Application of in-silico docking for green electrochemical quantification of prucalopride succinate in pharmaceutical, urine, and milk matrices

  2025cites this paper
• Development and Validation of a Bioanalytical Method for Estimation of Prucalopride in Human Plasma Using Liquid Chromatography–Tandem Mass Spectrometry

  2025cites this paper
• Nano-level assay of prucalopride by molecular size-based resonance Rayleigh scattering strategy: application to content uniformity test

  2024cites this paper
• Voltammetric and electro-kinetic assessment of prucalopride at MnO2-rGO fabricated pencil graphite electrode

  2024cites this paper
• An ingenious technique based on the usage of fluorone-based dye; pyrosin B in prucalopride assay in different matrices through an "on-off" dye native fluorescence probe.

  2024cites this paper
• Integrated resonance Rayleigh scattering approach utilizing Box–Behnken experimental design for the facile quantification of prucalopride in pharmaceutical tablets and human urine with sustainability assessment

  2024cites this paper
• Green microwave quantum dots as luminescent probes for quantifying prucalopride: consistency of content and application to pharmacokinetic studies

  2023influential citation
• Bioanalytical Validated Spectrofluorimetric Method for the Determination of Prucalopride succinate in Human Urine Samples and Its Greenness Evaluation

  2023cites this paper
• Eco-friendly-assessed micellar-fluorimetric platform for concurrent analysis of empagliflozin and prucalopride succinate in biological fluids: Docking simulation.

  2023cites this paper
• Sensitive spectrofluorimetric determination of the prokinetic drug; Prucalopride succinate, based on supramolecular aggregation approach with evaluation of method greenness: application to content uniformity test.

  2023cites this paper
• Novel sensing probe using Terbium-sensitized luminescence and 8-hydroxyquinoline for determination of prucalopride succinate: green assessment with Complex-GAPI and analytical Eco-Scale

  2022cites this paper
• A Validated Stability-Indicating Method for Separation of Prucalopride Drug by HPLC: Method Transfer to UPLC

  2021cites this paper
• An Entire Process Optimization Strategy for Comprehensive In Vivo Metabolite Profiling of Prucalopride in Rats Based on Ultra-Performance Liquid Chromatography With Q-Exactive Hybrid Quadrupole–Orbitrap High-Resolution Mass Spectrometry

  2021cites this paper
• Interpretation of tandem mass spectra of antiepileptic drugs using accurate-m/z data and m/z-shifts with stable-isotope labeled analogues

  2020cites this paper
• Development and Validation of a Stability Indicating RP-HPLC Method for the Determination of Prucalopride succinate in Bulk and Tablet

  2020cites this paper
• Ameliorative effects and possible molecular mechanisms of action of fibrauretine from Fibraurea recisa Pierre on d-galactose/AlCl3-mediated Alzheimer's disease

  2018cites this paper
• Chiisanoside, a triterpenoid saponin, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis

  2017cites this paper