Synthesis and X-Ray Structure of Important Anticancer Nucleosides Intermediate (2R,3S,4S,5R)-2-(acetoxymethyl)-5- (3-bromo-5-(methoxycarbonyl)- 1H-1,2,4-triazol-1-yl)tetrahydrofuran- 3,4-diyl Diacetate

An important anticancer nucleosides intermediate (2R,3S,4S,5R)-2-(acetoxymethyl)-5-(3-bromo-5-(methoxycar-bonyl)-1H-1,2,4-triazol-1-yl)tetrahydrofuran-3,4-diyl diacetate was synthesized by directly coupling the bromotriazole with the protected ribose sugar, and have given the corresponding product in moderate yield. Its structure and conformation were confirmed by single crystal X-ray diffraction.

• Publication year

  2014

• Venue

  Journal of Crystallization Process and Technology

• Publication date

  2014-06-23

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.4236/JCPT.2014.43018
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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