NF-κB activated by ER calcium release inhibits Aβ-mediated expression of CHOP protein: Enhancement by AD-linked mutant presenilin 1

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Experimental Neurology

• Publication date

  2007-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.EXPNEUROL.2007.04.009
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Enhanced Ryanodine‐Mediated Calcium Release in Mutant PS1‐Expressing Alzheimer's Mouse Models

  2007cited by this paper
• Suppression of Calcium Release from Inositol 1,4,5-Trisphosphate-sensitive Stores Mediates the Anti-apoptotic Function of Nuclear Factor-κB*

  2005cited by this paper
• Enhanced caffeine‐induced Ca2+ release in the 3xTg‐AD mouse model of Alzheimer's disease

  2005cited by this paper
• PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release.

  2005cited by this paper
• Toxicity of Amyloid β Peptide: Tales of Calcium, Mitochondria, and Oxidative Stress

  2004cited by this paper
• Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture.

  2004cited by this paper
• Induction of neuronal death by ER stress in Alzheimer's disease.

  2004cited by this paper
• Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5‐triphosphate receptors in the neurotoxic effects induced by the amyloid‐β peptide

  2004cited by this paper
• GDNF regulates the Aβ-induced endoplasmic reticulum stress response in rabbit hippocampus by inhibiting the activation of gadd 153 and the JNK and ERK kinases

  2004cited by this paper
• Roles of CHOP/GADD153 in endoplasmic reticulum stress

  2004cited by this paper
• Dysregulated IP3 Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation in Presenilin1 Results in Exaggerated Ca2+ Signals and Altered Membrane Excitability

  2004cited by this paper
• Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease.

  2003cited by this paper
• Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta‐amyloid peptide toxicity

  2003cited by this paper
• Inhibition of NF-kB Renders Cells more Vulnerable to Apoptosis Induced by Amyloid ß Peptides

  2003cited by this paper
• Molecular pathways of endoplasmic reticulum dysfunctions: possible cause of cell death in the nervous system.

  2003cited by this paper
• Endoplasmic reticulum Ca2+ homeostasis and neuronal death

  2003cited by this paper
• Neuronal and glial calcium signaling in Alzheimer's disease.

  2003cited by this paper
• Calcium dyshomeostasis and intracellular signalling in alzheimer's disease

  2002cited by this paper
• The endoplasmic reticulum: a multifunctional signaling organelle.

  2002cited by this paper
• Molecular Pathways of Protein Synthesis Inhibition during Brain Reperfusion: Implications for Neuronal Survival or Death

  2002cited by this paper
• Aβ(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-κB

  2001cited by this paper
• Endoplasmic Reticulum d-myo-Inositol 1,4,5-Trisphosphate-sensitive Stores Regulate Nuclear Factor-κB Binding Activity in a Calcium-independent Manner*

  2001cited by this paper
• Subcellular mechanisms of presenilin-mediated enhancement of calcium signaling.

  2001cited by this paper
• Repression of GADD153/CHOP by NF-κB: a possible cellular defense against endoplasmic reticulum stress-induced cell death

  2001cited by this paper
• Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.

  2001cited by this paper
• Mutant Presenilins Disturb Neuronal Calcium Homeostasis in the Brain of Transgenic Mice, Decreasing the Threshold for Excitotoxicity and Facilitating Long-term Potentiation*

  2001cited by this paper
• Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

  2001cited by this paper
• Cancer cell-derived interleukin 1alpha contributes to autocrine and paracrine induction of pro-metastatic genes in breast cancer.

  2000cited by this paper
• Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.

  2000cited by this paper
• Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal Ischemia In Vivo and to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis

  2000cited by this paper
• Nuclear Factor‐κB Mediates the Cell Survival‐Promoting Action of Activity‐Dependent Neurotrophic Factor Peptide‐9

  2000cited by this paper
• A Pathway of Neuronal Apoptosis Induced by Hypoxia/Reoxygenation

  2000cited by this paper
• Presenilin structure, function and role in Alzheimer disease.

  2000cited by this paper
• Presenilin Function in APP Processing

  2000cited by this paper
• Presenilin-1 P264L Knock-In Mutation: Differential Effects on Aβ Production, Amyloid Deposition, and Neuronal Vulnerability

  2000cited by this paper
• Substance P activates coincident NF-AT- and NF-kappa B-dependent adhesion molecule gene expression in microvascular endothelial cells through intracellular calcium mobilization.

  1999cited by this paper
• Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis.

  1999cited by this paper
• Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

  1999cited by this paper
• Alzheimer's Presenilin-1 Mutation Potentiates Inositol 1,4,5-Trisphosphate-Mediated Calcium Signaling in Xenopus

  1999cited by this paper
• Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons*

  1999cited by this paper
• Presenilin-2 Mutations Modulate Amplitude and Kinetics of Inositol 1,4,5-Trisphosphate-mediated Calcium Signals*

  1999cited by this paper
• CD40-mediated signal transduction in human airway smooth muscle.

  1998cited by this paper
• Secreted β-Amyloid Precursor Protein Counteracts the Proapoptotic Action of Mutant Presenilin-1 by Activation of NF-κB and Stabilization of Calcium Homeostasis*

  1998cited by this paper
• The ER-overload response: activation of NF-κB

  1997cited by this paper
• Activation of NF‐κB protects hippocampal neurons against oxidative stress‐induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

  1997cited by this paper
• Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells.

  1997cited by this paper
• Inhibition of nuclear factor kappa B (NFκB) activity induces nerve growth factor‐resistant apoptosis in PC12 cells

  1997cited by this paper
• Activation of NF‐κB by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers

  1996cited by this paper
• Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

  1996cited by this paper
• Activation of nuclear factor-kappaB via T cell receptor requires a Raf kinase and Ca2+ influx. Functional synergy between Raf and calcineurin.

  1996cited by this paper
• Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)

  1996cited by this paper
• Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

  1995cited by this paper
• Candidate gene for the chromosome 1 familial Alzheimer's disease locus

  1995cited by this paper
• Calcium, free radicals, and excitotoxic neuronal death in primary cell culture.

  1995cited by this paper
• A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF‐kappa B.

  1995cited by this paper
• Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.

  1994cited by this paper
• Regulation of the C/EBP-related gene gadd153 by glucose deprivation

  1993cited by this paper
• Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents

  1989cited by this paper

• Structural characterization of polysaccharide purified from Amanita caesarea and its pharmacological basis for application in Alzheimer's disease: endoplasmic reticulum stress.

  2021cites this paper
• Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo.

  2021cites this paper
• ER Stress Signaling in Alzheimer's Disease

  2020cites this paper
• Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin

  2019cites this paper
• The interplay between mitochondria-endoplasmic reticulum contacts and Alzheimer’s disease

  2019cites this paper
• Modelling and investigation of NMDAR-mediated calcium signalling at Hippocampal Dendritic Spine in Alzheimer’s disease

  2016cites this paper
• Endothelial cell's response to proteostatic dysregulation: pursuing the protective action of ghrelin

  2016cites this paper
• Ca2+ dysregulation in the endoplasmic reticulum related to Alzheimer's disease: A review on experimental progress and computational modeling

  2015influential citation
• Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.

  2015cites this paper
• Bcl-2 maintains the mitochondrial membrane potential, but fails to affect production of reactive oxygen species and endoplasmic reticulum stress, in sodium palmitate-induced β-cell death

  2014cites this paper
• New insights into the roles of CHOP-induced apoptosis in ER stress.

  2014cites this paper
• The Central Nervous System in Metabolic Syndrome

  2014cites this paper
• Endoplasmic Reticulum Dysfunction in Alzheimer’s Disease

  2014cites this paper
• Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease

  2013cites this paper
• Endoplasmic reticulum dysfunction in neurological disease.

  2013cites this paper
• Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.

  2012cites this paper
• Early Presynaptic and Postsynaptic Calcium Signaling Abnormalities Mask Underlying Synaptic Depression in Presymptomatic Alzheimer's Disease Mice

  2012cites this paper
• Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity.

  2011cites this paper
• Endoplasmic Reticulum Ca2+ Handling in Excitable Cells in Health and Disease

  2011cites this paper
• Involvement of endoplasmic reticulum stress-mediated CHOP (GADD153) induction in the cytotoxicity of 2-aminophenoxazine-3-one in cancer cells.

  2011cites this paper
• Recent Understanding of the Molecular Mechanisms of Alzheimer's Disease

  2011cites this paper
• TRAM1 is involved in disposal of ER membrane degradation substrates.

  2010cites this paper
• Hypothalamic lipotoxicity and the metabolic syndrome.

  2010cites this paper
• Mice knock out for the histone acetyltransferase p300/CREB binding protein-associated factor develop a resistance to amyloid toxicity.

  2010cites this paper
• ER Stress-Mediated Apoptotic Pathway Induced by Aβ Peptide Requires the Presence of Functional Mitochondria

  2010cites this paper
• Calcium Signaling and Amyloid Toxicity in Alzheimer Disease*

  2010cites this paper
• Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease.

  2010cites this paper
• Activation of eukaryotic initiation factor-2 α-kinases in okadaic acid-treated neurons.

  2010cites this paper
• p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity

  2009cites this paper
• HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

  2009cites this paper
• Effect of BSA-induced ER stress on SGLT protein expression levels and alpha-MG uptake in renal proximal tubule cells.

  2009cites this paper