Severe hypoxia and malnutrition collectively contribute to scar fibroblast inhibition and cell apoptosis

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Wound Repair and Regeneration

• Publication date

  2015-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/wrr.12343PMID 26174572
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011influential reference
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