HOXD13 Binds DNA Replication Origins To Promote Origin Licensing and Is Inhibited by Geminin

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Molecular and Cellular Biology

• Publication date

  2009-08-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.00509-09PMID 19703996PMCID PMC2772751
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The homeotic protein HOXC13 is a member of human DNA replication complexes

  2009cited by this paper
• Hoxd13 binds in vivo and regulates the expression of genes acting in key pathways for early limb and skeletal patterning.

  2008cited by this paper
• Mapping of an origin of DNA replication in the promoter of fragile X gene FMR1.

  2007cited by this paper
• Non-transcriptional control of DNA replication by c-Myc

  2007cited by this paper
• Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry

  2007cited by this paper
• Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression

  2006cited by this paper
• Hoxd13 and Hoxa13 Directly Control the Expression of the EphA7 Ephrin Tyrosine Kinase Receptor in Developing Limbs*

  2006cited by this paper
• The functional role of Cdc6 in S–G2/M in mammalian cells

  2006cited by this paper
• The regulation of embryonic patterning and DNA replication by geminin

  2005cited by this paper
• Geminin regulates neuronal differentiation by antagonizing Brg1 activity.

  2005cited by this paper
• The identification of Hoxc8 target genes.

  2005cited by this paper
• Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin

  2005cited by this paper
• Hox Genes: From Leukemia to Hematopoietic Stem Cell Expansion

  2005cited by this paper
• Eukaryotic origins of DNA replication: could you please be more specific?

  2005cited by this paper
• The Kinetic Status of Hematopoietic Stem Cell Subpopulations Underlies a Differential Expression of Genes Involved in Self‐Renewal, Commitment, and Engraftment

  2005cited by this paper
• Transcription factors and DNA replication origin selection

  2005cited by this paper
• Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells.

  2005cited by this paper
• Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia

  2005cited by this paper
• Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.

  2005cited by this paper
• HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis

  2004cited by this paper
• Site-specific Loading of an MCM Protein Complex in a DNA Replication Initiation Zone Upstream of the c-MYC Gene in the HeLa Cell Cycle*

  2004cited by this paper
• The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

  2004influential reference
• The destruction box of human Geminin is critical for proliferation and tumor growth in human colon cancer cells

  2004cited by this paper
• Direct interaction of geminin and Six3 in eye development

  2004cited by this paper
• FGF signaling antagonizes cytokine-mediated repression of Sox9 in SW1353 chondrosarcoma cells.

  2003cited by this paper
• Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia

  2003cited by this paper
• Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins.

  2003cited by this paper
• PBX1 nuclear export is regulated independently of PBX–MEINOX interaction by PKA phosphorylation of the PBC‐B domain

  2003cited by this paper
• Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression

  2003cited by this paper
• Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells.

  2003cited by this paper
• An I47L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function

  2003cited by this paper
• A novel technique with enhanced detection and quantitation of HPV-16 E1- and E2-mediated DNA replication.

  2003cited by this paper
• Cell type-specific responses of human cells to inhibition of replication licensing

  2002cited by this paper
• PII: S0925-4773(02)00008-4

  2002cited by this paper
• Identification of a Binding Region for Human Origin Recognition Complex Proteins 1 and 2 That Coincides with an Origin of DNA Replication

  2002cited by this paper
• The Origin Recognition Complex Marks a Replication Origin in the Human TOP1 Gene Promoter*

  2002cited by this paper
• Control of DNA replication licensing in a cell cycle

  2002cited by this paper
• Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.

  2000cited by this paper
• Selection of homeotic proteins for binding to a human DNA replication origin.

  2000cited by this paper
• Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

  2000cited by this paper
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  1999cited by this paper
• The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells.

  1999cited by this paper
• Specification of Regions of DNA Replication Initiation during Embryogenesis in the 65-KilobaseDNApolα-dE2F Locus of Drosophila melanogaster

  1999cited by this paper
• Homeobox genes and cancer.

  1999cited by this paper
• Hox genes in digit development and evolution

  1999cited by this paper
• Transcriptional targeting of retroviral vectors to the erythroblastic progeny of transduced hematopoietic stem cells.

  1999cited by this paper
• Cell Cycle-Regulated Expression of MammalianCDC6 Is Dependent on E2F

  1998cited by this paper
• An in vitro model to study mesenchymal-epithelial transformation.

  1998cited by this paper
• Geminin, an inhibitor of DNA replication, is degraded during mitosis.

  1998cited by this paper
• Cell Cycle-Regulated Expression of Mammalian CDC6 Is Dependent on E2F

  1998cited by this paper
• Cdc6 protein causes premature entry into S phase in a mammalian cell‐free system

  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
• An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

  1996cited by this paper
• A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse.

  1996cited by this paper
• Vertebrate Hox genes and proliferation: an alternative pathway to homeosis?

  1995cited by this paper
• Transition in Specification of Embryonic Metazoan DNA Replication Origins

  1995cited by this paper
• Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain.

  1994cited by this paper
• Hox genes in vertebrate development.

  1994cited by this paper
• Fine mapping of a replication origin of human DNA.

  1994influential reference
• Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs.

  1993cited by this paper
• Production of high-titer helper-free retroviruses by transient transfection.

  1993influential reference
• Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins.

  1992cited by this paper
• A cultured human renal epithelioid cell line responsive to vasoactive intestinal peptide

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• Early events in murine erythroleukemia cells induced to differentiate: variation of the cell cycle parameters in relation to p53 accumulation.

  1988influential reference
• Selective extraction of polyoma DNA from infected mouse cell cultures.

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• Posttranscriptional RNA stabilization of telomeric RNAs FRG2, DBE-T, D4Z4 at human 4q35 in response to genotoxic stress and D4Z4 macrosatellite repeat length

  2025cites this paper
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  2024cites this paper
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  2024cites this paper
• Irreducible Complexity of Hox Gene: Path to the Canonical Function of the Hox Cluster

  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2022cites this paper
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  2020cites this paper
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  2020cites this paper
• Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication.

  2018cites this paper
• Research progress and clinical application of tumor markers in medical laboratory science

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• Geminin a multi task protein involved in cancer pathophysiology and developmental process: A review.

  2016cites this paper
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  2016cites this paper
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  2015cites this paper
• ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

  2015cites this paper
• Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1

  2015cites this paper
• MicroRNA-196b is transcribed from an autonomous promoter and is directly regulated by Cdx2 and by posterior Hox proteins during embryogenesis.

  2015cites this paper
• Non‐transcriptional interactions of Hox proteins: Inventory, facts, and future directions

  2014influential citation
• Tracking context‐specific transcription factors regulating hox activity

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• Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells

  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012influential citation
• The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

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