The influence of organochlorine compound exposure on the physiological development of children

catalaAquest estudi resumeix els avencos en el coneixement dels trastorns de salut associats a l’exposicio fetal a compostos organoclorats en una cohort de nens de Menorca. S’ha observat una incidencia major de diversos efectes perjudicials per la salut als 4 anys d’edat, per exemple, hexaclorobenze (HCB) i comportament social pobre i trastorn per deficit d’atencio amb hiperactivitat, 4,4’- DDE i asma, xiulets pulmonars, infeccions de les vies respiratories baixes i alteracio de coproporfirines urinaries, HCB, s-hexaclorociclohexa i 4,4’-DDE i alteracio de les hormones tiroidals, HCB, 4,4’-DDE i policlorobifenils (PCBs) i sobrepes, 4,4’-DDT i PCBs i menor desenvolupament neurologic. Tambe s’ha documentat un efecte protector de la lactancia materna contra la disminucio de les habilitats cognitives dels nens a causa de l’exposicio a 4,4’-DDT. Aquest efecte protector mostra que altres factors, a mes de l’exposicio a contaminants i genetica personal, influeixen en els efectes de salut dels contaminants ambientals en les poblacions humanes. Aquests resultats son importants per comprendre les implicacions per la salut dels estudis d’exposomes. EnglishThe present study summarizes the advances on the knowledge of the health disturbances associated to fetal exposure to organochlorine compounds in a cohort of children from Menorca. Higher incidence of diverse deleterious health effects at 4 years of age have been observed, e.g. hexachlorobenzene (HCB) and poor social behavior and attention-deficit hyperactivity disorder, 4,4’-DDE and asthma, wheeze, lower respiratory tract infections and alteration of urinary coproporphyrins, HCB, s-hexachlorocyclohexane and 4,4’-DDE and alteration of thyroid hormones, HCB, 4,4’-DDE and polychlorobiphenyls (PCBs) and overweight, 4,4’-DDT and PCBs and lower neurodevelopment. A protective effect of breastfeeding against decreases of cognitive skills in children due to 4,4’-DDT exposure has also been documented. This protective effect shows that other factors besides pollutant exposure and genetic variability influence on the health effects of environmental pollutants into human populations. These results are important for the understanding of the health implications of exposome studies.

• Publication year

  2014

• Venue

  Unknown venue

• Publication date

  2014-10-11

• Fields of study

  Biology, Geography

• Identifiers
  DOI 10.3306/MEDICINABALEAR.29.03.25
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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