N-Substituted valienamines, alpha-glucosidase inhibitors.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Journal of antibiotics (Tokyo. 1968)

• Publication date

  1982-11-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.7164/ANTIBIOTICS.35.1624PMID 6761330
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An example of enzyme hysteresis. The slow and tight interaction of some fully competitive inhibitors with small intestinal sucrase.

  1981cited by this paper
• Valienamine as an alpha-glucosidase inhibitor.

  1980cited by this paper
• New cyclitols, degradation of validamycin A by Flavobacterium saccharophilum.

  1980cited by this paper
• Glucosidase inhibition

  1977cited by this paper
• A probable oxocarbonium ion in the reaction mechanism of small intestinal sucrase and isomaltase.

  1975cited by this paper
• The unsaturated cyclitol part of the new antibiotics, the validamycins

  1972cited by this paper
• METHOD FOR ASSAY OF INTESTINAL DISACCHARIDASES.

  1964cited by this paper
• Cellular Localization, Solubilization and Separation of Intestinal Glycosidases.

  1958cited by this paper

• Design and synthesis of biologically active carbaglycosylamines: From glycosidase inhibitors to pharmacological chaperones

  2022cites this paper
• Biosynthesis and Biological Activity of Carbasugars

  2016cites this paper
• Total syntheses of five uvacalols: structural validation of uvacalol A, uvacalol B and uvacalol C and disproval of the structures of uvacalol E and uvacalol G.

  2015cites this paper
• Synthesis and α‐Glucosidase and α‐Amylase Inhibitory Activity Evaluation of Azido‐ and Aminocyclitols

  2014cites this paper
• Diastereospecific epoxidation and highly regioselective ring-opening of (+)-valienamine: practical synthesis of (+)-valiolamine

  2013cites this paper
• Vinylogy in orthoester hydrolysis: total syntheses of cyclophellitol, valienamine, gabosine K, valienone, gabosine G, 1-epi-streptol, streptol, and uvamalol A.

  2013cites this paper
• Bromodimethylsulfonium bromide (BDMS) mediated dithioacetalization of carbohydrates under solvent-free conditions.

  2010cites this paper
• Synthesis of valiolamine and some precursors for bioactive carbaglycosylamines from (-)-vibo-quercitol produced by biogenesis of myo-inositol.

  2007cites this paper
• 1.21 – Glycosidase Inhibitors: Structure, Activity, Synthesis, and Medical Relevance

  2007cites this paper
• Conduramine F-1 epoxides: synthesis and their glycosidase inhibitory activities

  2007cites this paper
• Search for alpha-glucosidase inhibitors: new N-substituted valienamine and conduramine F-1 derivatives.

  2006cites this paper
• Synthesis of amino- and diaminoconduritols and their applications

  2006cites this paper
• Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors.

  2006cites this paper
• An efficient synthesis of valienamine via ring-closing metathesis.

  2005cites this paper
• Ring closing metathesis in the synthesis of biologically interesting peptidomimetics, sugars and alkaloids.

  2005cites this paper
• Quantitative analysis of valienamine in the microbial degradation of validamycin A after derivatization with p-nitrofluorobenzene by reversed-phase high-performance liquid chromatography.

  2005cites this paper
• Total asymmetric synthesis of (-)-conduramine B-1 and of its enantiomer. N-Benzyl derivatives of conduramine B-1 are beta-glucosidase inhibitors.

  2005cites this paper
• Preparation of Versatile Synthetic Precursors of Optically Active 5a‐Carba‐sugars from (−)‐vibo‐Quercitol

  2005cites this paper
• Microbial transformation of validamycin A to valienamine by immobilized cells

  2005cites this paper
• Properties and production of valienamine and its related analogues.

  2003cites this paper
• The C7N aminocyclitol family of natural products.

  2003cites this paper
• A new synthesis of valienamine.

  2001cites this paper
• A new synthetic approach towards N-alkylated 2-epi-valienamines via palladium-catalyzed coupling reaction

  2000cites this paper
• Synthesis of polyhydroxylated cyclohexenyl sulfides and sulfoxides. Evaluation of their inhibitory activity on α- and β-d-glucosidases

  1999cites this paper
• Enantiospecific Syntheses of Valienamine and 2-epi-Valienamine(1).

  1999cites this paper
• Preparation and biological activity of manno- and galacto-validamines, new 5a-carba-glycosylamines as alpha-glycosidase inhibitors.

  1997cites this paper
• Preparation and biological activity of manno- and galacto-validamines, new 5a-carba-glycosylamines as α-glycosidase inhibitors

  1997cites this paper
• β-Glucosidase inhibitors incorporating pyridinium as a glucosyl mimic

  1995cites this paper
• Intramolecular amino delivery reactions for the synthesis of valienamine and analogues

  1992cites this paper
• Castanospermine-glucosides as selective disaccharidase inhibitors.

  1990cites this paper
• Hexa-O-benzyl-5-hydroxy-pseudo-α-D-glucopyranose and its C-5 epimer

  1990cites this paper
• Microbial α-Glucosidase Inhibitors: Chemistry, Biochemistry, and Therapeutic Potential

  1988cites this paper
• Synthesis of seven penta-N,O-acetyl-pseudo-2-amino-2-deoxy-dl-hexopyranoses

  1988cites this paper
• [Antibiotic formation by gram-negative nonsporulating bacteria].

  1986cites this paper
• Synthesis and alpha-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents.

  1986cites this paper
• Stereoselective conversion of valienamine and validamine into valiolamine

  1985cites this paper
• A one pot tritiation of aminoglycoside antibiotics.

  1983cites this paper