Pathway analysis using 13C‐glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Molecular Microbiology

• Publication date

  2016-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/mmi.13313PMID 26691313
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones

  2015cited by this paper
• Amino Acid Uptake and Metabolism of Legionella pneumophila Hosted by Acanthamoeba castellanii*

  2014cited by this paper
• Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella‐containing vacuoles from macrophages

  2014cited by this paper
• Staphylococcus aureus small colony variants show common metabolic features in central metabolism irrespective of the underlying auxotrophism

  2014cited by this paper
• The natural alternative: protozoa as cellular models for Legionella infection

  2014cited by this paper
• A Type IV Translocated Legionella Cysteine Phytase Counteracts Intracellular Growth Restriction by Phytate

  2014cited by this paper
• Metabolic flux pattern of glucose utilization by Xanthomonas campestris pv. campestris: prevalent role of the Entner-Doudoroff pathway and minor fluxes through the pentose phosphate pathway and glycolysis.

  2014cited by this paper
• Analysis of carbon substrates used by Listeria monocytogenes during growth in J774A.1 macrophages suggests a bipartite intracellular metabolism

  2014cited by this paper
• Utilization of host‐derived cysteine‐containing peptides overcomes the restricted sulphur metabolism of Campylobacter jejuni

  2014cited by this paper
• 13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

  2013cited by this paper
• The intracellular metabolism of legionella by isotopologue profiling.

  2013cited by this paper
• Exploring Anti-Bacterial Compounds against Intracellular Legionella

  2013cited by this paper
• The phtC-phtD Locus Equips Legionella pneumophila for Thymidine Salvage and Replication in Macrophages

  2013cited by this paper
• The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit.

  2013cited by this paper
• A Defined, Glucose-Limited Mineral Medium for the Cultivation of Listeria spp

  2013cited by this paper
• The Legionella effector RidL inhibits retrograde trafficking to promote intracellular replication.

  2013cited by this paper
• A Rab-centric perspective of bacterial pathogen-occupied vacuoles.

  2013cited by this paper
• Legionella oakridgensis ATCC 33761 genome sequence and phenotypic characterization reveals its replication capacity in amoebae.

  2013cited by this paper
• Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence

  2013cited by this paper
• Phosphoinositide lipids and the Legionella pathogen vacuole.

  2013cited by this paper
• Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection

  2013cited by this paper
• Secretive Bacterial Pathogens and the Secretory Pathway

  2012cited by this paper
• Metabolic Responses of Primary and Transformed Cells to Intracellular Listeria monocytogenes

  2012cited by this paper
• Characterisation of Legionella pneumophila phospholipases and their impact on host cells.

  2011cited by this paper
• Characterization of Central Carbon Metabolism of Streptococcus pneumoniae by Isotopologue Profiling*

  2011cited by this paper
• Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth

  2011cited by this paper
• Defective macrophage function in aquaporin‐3 deficiency

  2011cited by this paper
• Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages

  2010influential reference
• Isotopologue Profiling of Legionella pneumophila

  2010cited by this paper
• The Legionella pneumophila F‐box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

  2010cited by this paper
• Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.

  2010cited by this paper
• Modulation of host cell function by Legionella pneumophila type IV effectors.

  2010cited by this paper
• Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

  2010cited by this paper
• Glucose Metabolism in Legionella pneumophila: Dependence on the Entner-Doudoroff Pathway and Connection with Intracellular Bacterial Growth

  2010influential reference
• Legionella pneumophila pangenome reveals strain-specific virulence factors

  2010cited by this paper
• The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

  2009cited by this paper
• Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa

  2009cited by this paper
• Mechanisms and methods in glucose metabolism and cell death.

  2008cited by this paper
• The phagosomal nutrient transporter (Pht) family.

  2008cited by this paper
• Carbon metabolism of Listeria monocytogenes growing inside macrophages

  2008cited by this paper
• Role of GldA in dihydroxyacetone and methylglyoxal metabolism of Escherichia coli K12.

  2008cited by this paper
• Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

  2007cited by this paper
• The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA

  2007cited by this paper
• Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila

  2006cited by this paper
• The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.

  2006cited by this paper
• Dictyostelium as host model for pathogenesis

  2005cited by this paper
• The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages.

  2005cited by this paper
• Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5

  2005cited by this paper
• Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

  2004cited by this paper
• Differentiate to thrive: lessons from the Legionella pneumophila life cycle

  2004cited by this paper
• The Genomic Sequence of the Accidental Pathogen Legionella pneumophila

  2004influential reference
• Proton Transport in Maize Tonoplasts Supported by Fructose-1,6-Bisphosphate Cleavage. Pyrophosphate-Dependent Phosphofructokinase as a Pyrophosphate-Regenerating System1

  2003cited by this paper
• Properties of the Glucose-6-Phosphate Transporter from Chlamydia pneumoniae (HPTcp) and the Glucose-6-Phosphate Sensor from Escherichia coli (UhpC)

  2002cited by this paper
• Kinetic analysis of PPi-dependent phosphofructokinase from Porphyromonas gingivalis.

  2002cited by this paper
• Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria

  2001cited by this paper
• Decreased Glucose Transporter Expression Triggers BAX-dependent Apoptosis in the Murine Blastocyst*

  2000cited by this paper
• Expression of Legionella pneumophilaVirulence Traits in Response to Growth Conditions

  1998cited by this paper
• Mutagenesis of Legionella pneumophila using Jn903 dllIacZ: identification of a growth‐phase‐regulated pigmentation gene

  1994cited by this paper
• Metabolism of methylglyoxal in microorganisms.

  1984cited by this paper
• Metabolic pathways and nitrogen metabolism inLegionella pneumophila

  1984cited by this paper
• Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources

  1983cited by this paper
• Amino acid requirements for Legionella pneumophila growth

  1981cited by this paper
• Chemically defined medium for Legionella pneumophila growth

  1981influential reference
• Development of a chemically defined liquid medium for growth of Legionella pneumophila

  1979cited by this paper
• Nonenzymic formation of toxic levels of methylglyoxal from glycerol and dihydroxyacetone in Ringer's phosphate suspensions of avian spermatozoa.

  1973cited by this paper

• Molecular evolution and adaptations of Legionella pneumophila from amoebae hosts to macrophages.

  2026cites this paper
• Regulation of ribosome hibernation controls Legionella survival, infection, antibiotic tolerance, and phenotypic heterogeneity

  2026influential citation
• Mucin stimulates the growth of Legionella pneumophila.

  2026cites this paper
• Expansion, restructuring and characterization of the Legionellaceae family

  2025cites this paper
• Versatile regulation of effectors by novel orthologous regulators in the Legionella genus

  2025cites this paper
• Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of Mycobacterium abscessus in macrophages

  2025cites this paper
• The unique Legionella longbeachae capsule favors intracellular replication and immune evasion

  2024cites this paper
• Molecular insights and functional analysis of isocitrate dehydrogenase in two gram-negative pathogenic bacteria

  2024cites this paper
• Roles of Critical Amino Acids Metabolism in The Interactions Between Intracellular Bacterial Infection and Macrophage Function

  2024cites this paper
• Why is manganese so valuable to bacterial pathogens?

  2023cites this paper
• Molecular regulation of virulence in Legionella pneumophila

  2023cites this paper
• Tapping lipid droplets: A rich fat diet of intracellular bacterial pathogens

  2023cites this paper
• Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae

  2023cites this paper
• The large GTPase Sey1/atlastin mediates lipid droplet- and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila

  2023cites this paper
• An Insight into the Microbiology, Epidemiology, and Host Cell Biology of Legionella Pneumophila: A Review of Literature

  2022cites this paper
• Linear programming based gene expression model (LPM-GEM) predicts the carbon source for Bacillus subtilis

  2022cites this paper
• Cellular cholesterol licenses Legionella pneumophila intracellular replication in macrophages

  2022cites this paper
• The inside scoop: Comparative genomics of two intranuclear bacteria, “Candidatus Berkiella cookevillensis” and “Candidatus Berkiella aquae”

  2022cites this paper
• Hiding in the yolk: A unique feature of Legionella pneumophila infection of zebrafish

  2022cites this paper
• A central role of sibling sRNAs NgncR_162/163 in main metabolic pathways of Neisseria gonorrhoeae

  2022cites this paper
• The Legionella Lqs-LvbR Regulatory Network Controls Temperature-Dependent Growth Onset and Bacterial Cell Density

  2021cites this paper
• Persistence of Intracellular Bacterial Pathogens—With a Focus on the Metabolic Perspective

  2021influential citation
• The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella

  2021cites this paper
• Metabolic adaption of Legionella pneumophila during intracellular growth in Acanthamoeba castellanii.

  2021cites this paper
• Substrate usage determines carbon flux via the citrate cycle in Helicobacter pylori

  2021cites this paper
• Conditional impairment of Coxiella burnetii by glucose-6P dehydrogenase activity

  2021cites this paper
• Metabolic evolutionary roots of the macrophage immune response in amoeba-bacteria interactions: The conserved role of hypoxia-induced Factor and AMP kinase.

  2021cites this paper
• Isotopologue Profiling of Infectious Disease

  2021cites this paper
• Zebrafish larvae as a powerful model to dissect protective innate immunity in response to Legionella pneumophila infection

  2021cites this paper
• Dissecting Host-Pathogen Interactions in TB Using Systems-Based Omic Approaches

  2021cites this paper
• Myo-Inositol as a carbon substrate in Francisella and insights into the metabolism of Francisella sp. strain W12-1067.

  2020cites this paper
• Untersuchungen zum Export, zur Membranassoziation und Aktivität der Phospholipase A PlaB von Legionella pneumophila

  2020cites this paper
• The Pathometabolism of Legionella Studied by Isotopologue Profiling.

  2019cites this paper
• Modulation of host cell metabolism by T4SS-encoding intracellular pathogens.

  2019cites this paper
• Screen for fitness and virulence factors of Francisella sp. strain W12-1067 using amoebae.

  2019cites this paper
• Immunometabolism at the interface between macrophages and pathogens

  2019cites this paper
• How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication

  2019cites this paper
• Nutrition and Bipartite Metabolism of Intracellular Pathogens.

  2019cites this paper
• Analysis of Legionella Metabolism by Pathogen Vacuole Proteomics.

  2018cites this paper
• A Legionella pneumophila amylase is essential for intracellular replication in human macrophages and amoebae

  2018cites this paper
• Nutritional virulence of Legionella pneumophila.

  2018influential citation
• Mammalian Solute Carrier (SLC)-like transporters of Legionella pneumophila

  2018cites this paper
• Evolution of the Arsenal of Legionella pneumophila Effectors To Modulate Protist Hosts

  2018cites this paper
• The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism

  2018influential citation
• Analysis of Piscirickettsia salmonis Metabolism Using Genome-Scale Reconstruction, Modeling, and Testing

  2017cites this paper
• The Flagellar Regulon of Legionella—A Review

  2017cites this paper
• Biphasic Metabolism and Host Interaction of a Chlamydial Symbiont

  2017cites this paper
• Differential Substrate Usage and Metabolic Fluxes in Francisella tularensis Subspecies holarctica and Francisella novicida

  2017cites this paper
• Multiple Substrate Usage of Coxiella burnetii to Feed a Bipartite Metabolic Network

  2017cites this paper
• Metabolic adaptation of intracellular bacteria and fungi to macrophages.

  2017cites this paper
• Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism

  2017cites this paper
• Formation of the Legionella-containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics.

  2017cites this paper
• Intra-Species and Inter-Kingdom Signaling of Legionella pneumophila

  2017cites this paper
• The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system

  2017cites this paper
• Metabolic adaptation of Chlamydia trachomatis to mammalian host cells

  2017cites this paper
• The life stage‐specific pathometabolism of Legionella pneumophila

  2016cites this paper
• Decoding Biosynthetic Pathways in Plants by Pulse-Chase Strategies Using 13CO2 as a Universal Tracer †

  2016cites this paper
• Metabolism of myo-Inositol by Legionella pneumophila Promotes Infection of Amoebae and Macrophages

  2016cites this paper
• MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis

  2016cites this paper