Strain specificities in age‐related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Experimental Gerontology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.exger.2017.11.002PMID 29128575
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats.

  2017cited by this paper
• Murine Cytomegalovirus Infection Induces Susceptibility to EAE in Resistant BALB/c Mice

  2017cited by this paper
• GM-CSF-Producing Th Cells in Rats Sensitive and Resistant to Experimental Autoimmune Encephalomyelitis

  2016cited by this paper
• Regulatory T cells control strain specific resistance to Experimental Autoimmune Prostatitis

  2016cited by this paper
• Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury

  2016cited by this paper
• Mesenchymal Stem Cells Modulate Light-induced Activation of Retinal Microglia Through CX3CL1/CX3CR1 Signaling

  2016cited by this paper
• Cytomegalovirus: a culprit or protector in multiple sclerosis?

  2015cited by this paper
• CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis.

  2015cited by this paper
• T cells in the control of organ-specific autoimmunity.

  2015cited by this paper
• Identifying genetic determinants of autoimmunity and immune dysregulation.

  2015cited by this paper
• Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats

  2015cited by this paper
• Male rats develop more severe experimental autoimmune encephalomyelitis than female rats: sexual dimorphism and diergism at the spinal cord level.

  2015cited by this paper
• Age- and location-related changes in microglial function.

  2015cited by this paper
• Change of paradigm: CD8+ T cells as important helper for CD4+ T cells during asthma and autoimmune encephalomyelitis

  2015cited by this paper
• Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation.

  2014cited by this paper
• Proteomic analysis.

  2014cited by this paper
• Immune regulation of multiple sclerosis by CD8+ T cells

  2014cited by this paper
• Age-associated changes in rat immune system: lessons learned from experimental autoimmune encephalomyelitis.

  2014cited by this paper
• Immune regulation of multiple sclerosis.

  2014cited by this paper
• Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories

  2014cited by this paper
• Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.

  2014cited by this paper
• Dysregulation of T Lymphocyte Proliferative Responses in Autoimmunity

  2014cited by this paper
• CD8⁺ T cell help is required for efficient induction of EAE in Lewis rats.

  2013cited by this paper
• Uveitis in Mouse and Man

  2013cited by this paper
• Elevated Expression of Fractalkine (CX3CL1) and Fractalkine Receptor (CX3CR1) in the Dorsal Root Ganglia and Spinal Cord in Experimental Autoimmune Encephalomyelitis: Implications in Multiple Sclerosis-Induced Neuropathic Pain

  2013cited by this paper
• Age-related autoimmunity

  2013cited by this paper
• Role of Microglia in CNS Autoimmunity

  2013cited by this paper
• IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.

  2013cited by this paper
• Overview of the epidemiology, diagnosis, and disease progression associated with multiple sclerosis.

  2013cited by this paper
• Increased micro-RNA 29b in the aged brain correlates with the reduction of insulin-like growth factor-1 and fractalkine ligand.

  2013cited by this paper
• Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.

  2012cited by this paper
• Immune aging and autoimmunity

  2012cited by this paper
• Mechanism of experimental autoimmune encephalomyelitis in Lewis rats: recent insights from macrophages

  2012cited by this paper
• Age-related changes in CD8 T cell homeostasis and immunity to infection.

  2012cited by this paper
• Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells

  2012cited by this paper
• TGF‐β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

  2012cited by this paper
• The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

  2011cited by this paper
• Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brains.

  2011cited by this paper
• CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity

  2011cited by this paper
• Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.

  2011cited by this paper
• CXCR3 in T cell function.

  2011cited by this paper
• Viral triggers of multiple sclerosis

  2010cited by this paper
• Regulation of tau pathology by the microglial fractalkine receptor.

  2010cited by this paper
• Th1 and Th17 cells

  2010cited by this paper
• Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge.

  2010cited by this paper
• Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide

  2010cited by this paper
• T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

  2010cited by this paper
• Fractalkine‐induced activation of the phosphatidylinositol‐3 kinase pathway attentuates microglial activation in vivo and in vitro

  2009cited by this paper
• Naturally-existing CD4(+)CD25(+)Foxp3(+) regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen.

  2009cited by this paper
• Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss.

  2009cited by this paper
• Potential Triggers of MS

  2009cited by this paper
• CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model.

  2009cited by this paper
• Molecular genetic dissection of the zebrafish olfactory system.

  2009cited by this paper
• Strain-dependent inflammatory responsiveness of rat microglial cells.

  2009cited by this paper
• End-stage dying glioma cells are engulfed by mouse microglia with a strain-dependent efficacy.

  2008cited by this paper
• Regulation of haeme oxygenase‐1 for treatment of neuroinflammation and brain disorders

  2008cited by this paper
• Induction, function and regulation of IL‐17‐producing T cells

  2008cited by this paper
• Differential effects of age on circulating and splenic leukocyte populations in C57BL/6 and BALB/c male mice

  2008cited by this paper
• Microglia derived from aging mice exhibit an altered inflammatory profile

  2007cited by this paper
• Cytokine-induced IL-10-secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage.

  2006cited by this paper
• Differential Pattern Recognition Receptor Expression but Stereotyped Responsiveness in Rat Spleen Dendritic Cell Subsets1

  2006cited by this paper
• Increased HO-1 expression and decreased iNOS expression in the hippocampus from adult spontaneously hypertensive rats

  2006cited by this paper
• Proteomic analysis of microglial contribution to mouse strain–dependent dopaminergic neurotoxicity

  2006cited by this paper
• Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

  2006cited by this paper
• Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression1

  2006cited by this paper
• Control of microglial neurotoxicity by the fractalkine receptor

  2006cited by this paper
• The why and how of thymocyte negative selection.

  2006cited by this paper
• Comparative gene expression analysis of NKT cell subpopulations

  2006cited by this paper
• Strain difference in susceptibility to experimental autoimmune encephalomyelitis between Albino Oxford and Dark Agouti rats correlates with disparity in production of IL‐17, but not nitric oxide

  2006cited by this paper
• Age‐related changes in the development of experimental autoimmune encephalomyelitis

  2005cited by this paper
• Natural Recovery and Protection from Autoimmune Encephalomyelitis: Contribution of CD4+CD25+ Regulatory Cells within the Central Nervous System1

  2005cited by this paper
• Genetic dissection of neurodegeneration and CNS inflammation.

  2005cited by this paper
• CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin

  2005cited by this paper
• Functional and Genetic Analysis of Two CD8 T Cell Subsets Defined by the Level of CD45RC Expression in the Rat1

  2004cited by this paper
• Exacerbation of experimental autoimmune encephalomyelitis in rodents infected with murine gammaherpesvirus‐68

  2003cited by this paper
• Differential Expression of the Chemokine Receptors CX3CR1 and CCR1 by Microglia and Macrophages in Myelin‐Oligodendrocyte‐Glycoprotein‐Induced Experimental Autoimmune Encephalomyelitis

  2003cited by this paper
• Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS

  2002cited by this paper
• Prolonged IFN-γ–producing NKT response induced with α-galactosylceramide–loaded DCs

  2002cited by this paper
• Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

  2002cited by this paper
• CD11b expression as a marker to distinguish between recently activated effector CD8(+) T cells and memory cells.

  2001cited by this paper
• Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation.

  2000cited by this paper
• Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes.

  2000cited by this paper
• Fractalkine modulates TNF‐α secretion and neurotoxicity induced by microglial activation

  2000cited by this paper
• Differential expression of

  1999cited by this paper
• Immunosenescence: impact in the young as well as the old?

  1999cited by this paper
• Immunosenescence: impact in the young as well as the old?

  1999cited by this paper
• Regulatory T cells in experimental allergic encephalomyelitis. III. Comparison of disease resistance in Lewis and Fischer 344 rats

  1999cited by this paper
• Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis.

  1998cited by this paper
• Rat NKR‐P1+ CD3+ T cells: selective proliferation in interleukin‐2, diverse T‐cell‐receptor‐Vβ repertoire and polarized interferon‐γ expression

  1998cited by this paper
• Mechanism of V(D)J recombination.

  1996cited by this paper
• Comprehensive Neurology

  1992cited by this paper
• Splenic and inguinal lymph node T cells of aged mice respond differently to polyclonal and antigen-specific stimuli.

  1992cited by this paper
• Studies of experimental allergic encephalomyelitis in old mice.

  1990cited by this paper
• GENETICS OF SUSCEPTIBILITY TO EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS STUDIED IN THREE RAT STRAINS

  1978cited by this paper
• Immunopathology of aging.

  1974cited by this paper
• Transcriptional Profiling of

  year unknowncited by this paper
• The FASEB Journal • Research Communication The neuronal chemokine CX3CL1/fractalkine

  year unknowncited by this paper
• International Journal of Molecular Sciences the Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (cns) Autoimmunity

  year unknowncited by this paper

• β-Adrenoceptor Blockade Moderates Neuroinflammation in Male and Female EAE Rats and Abrogates Sexual Dimorphisms in the Major Neuroinflammatory Pathways by Being More Efficient in Males

  2022cites this paper
• Thymic changes as a contributing factor in the increased susceptibility of old Albino Oxford rats to EAE development.

  2022cites this paper
• Infrared radiation from cage bedding moderates rat inflammatory and autoimmune responses in collagen-induced arthritis

  2021cites this paper
• Sex-specific remodeling of T-cell compartment with aging: implications for rat susceptibility to central nervous system autoimmune diseases.

  2021cites this paper
• Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain

  2020cites this paper
• CD8+ T Cell-Mediated Mechanisms Contribute to the Progression of Neurocognitive Impairment in Both Multiple Sclerosis and Alzheimer's Disease?

  2020cites this paper
• Strain differences in thymic atrophy in rats immunized for EAE correlate with the clinical outcome of immunization

  2018cites this paper