Deficient mismatch repair phenotype is a prognostic factor for colorectal cancer in elderly patients.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Digestive and Liver Disease

• Publication date

  2013-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.dld.2012.09.013PMID 23102497
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

  2011cited by this paper
• A mini geriatric assessment helps treatment decision in elderly patients with digestive cancer. A pilot study.

  2011cited by this paper
• Defective Mismatch Repair Status as a Prognostic Biomarker of Disease-Free Survival in Stage III Colon Cancer Patients Treated with Adjuvant FOLFOX Chemotherapy

  2011cited by this paper
• Association between a high number of isolated lymph nodes in T1 to T4 N0M0 colorectal cancer and the microsatellite instability phenotype.

  2010cited by this paper
• Prognostic impact of microsatellite instability in colorectal cancer patients treated with adjuvant FOLFOX.

  2010cited by this paper
• Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer.

  2010cited by this paper
• A quantitative multigene RT-PCR assay for prediction of recurrence in stage II colon cancer: Selection of the genes in four large studies and results of the independent, prospectively designed QUASAR validation study.

  2009cited by this paper
• Impact of older age on the efficacy of newer adjuvant therapies in >12,500 patients (pts) with stage II/III colon cancer: Findings from the ACCENT Database.

  2009influential reference
• Half of elderly patients routinely treated for colorectal cancer receive a sub-standard treatment.

  2009cited by this paper
• Prognostic Significance of Defective Mismatch Repair and BRAF V600E in Patients with Colon Cancer

  2008cited by this paper
• Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study.

  2007cited by this paper
• Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study.

  2007cited by this paper
• Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.

  2006cited by this paper
• Systematic review of microsatellite instability and colorectal cancer prognosis.

  2005cited by this paper
• Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer

  2005cited by this paper
• Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.

  2004cited by this paper
• American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer.

  2004cited by this paper
• Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas

  2004cited by this paper
• Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer.

  2004cited by this paper
• Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer.

  2003cited by this paper
• Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.

  2002cited by this paper
• Colon cancer in France: evidence for improvement in management and survival

  2002cited by this paper
• Chemotherapy for colon cancer in a well‐defined French population: is it under‐ or over‐prescribed?

  2002cited by this paper
• Age and adjuvant chemotherapy use after surgery for stage III colon cancer.

  2001cited by this paper
• A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients.

  2001cited by this paper
• Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers.

  1999cited by this paper
• Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators.

  1995cited by this paper
• Efficacy of adjuvant fluorouracil and folinic acid in colon cancer

  1995cited by this paper
• Microsatellite instability in cancer of the proximal colon.

  1993cited by this paper
• Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.

  1990cited by this paper

• Polyphenol Intake in Elderly Patients: A Novel Approach to Counteract Colorectal Cancer Risk?

  2025cites this paper
• Risk of Lymph Node Metastasis in T2 Colon Cancer: A Nationwide Population-Based Cohort Study

  2025cites this paper
• Oncogériatrie : cancers digestifs des patients âgés

  2025cites this paper
• Non-metastatic colon cancer: French Intergroup Clinical Practice Guidelines for diagnosis, treatments, and follow-up (TNCD, SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, SFP, AFEF, and SFR).

  2024cites this paper
• Lymphatic spread patterns in young versus elderly patients with stage III colon cancer

  2024cites this paper
• Oxaliplatin-Based Adjuvant Chemotherapy in Older Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 12 Trials

  2024cites this paper
• Aging and cancer: Clinical role of tumor markers in the geriatric population (Review)

  2024cites this paper
• Navigating through novelties concerning mCRC treatment—the role of immunotherapy, chemotherapy, and targeted therapy in mCRC

  2024cites this paper
• Guidance for Treating the Older Adults with Colorectal Cancer

  2023cites this paper
• Prise en charge du cancer du côlon après résection curative

  2023cites this paper
• Preliminary tolerance analysis of adjuvant chemotherapy in older patients after resection of stage III colon cancer from the PRODIGE 34-FFCD randomized trial.

  2022cites this paper
• Management of Metastatic Colorectal Carcinoma in Older Adults: Balancing Risks and Benefits of Novel Therapies

  2021cites this paper
• Is cancer biology different in older patients?

  2021cites this paper
• Rate of dissemination and prognosis in early and advanced stage colorectal cancer based on microsatellite instability status: systematic review and meta-analysis

  2021cites this paper
• PREVALENCE AND PROGNOSIS OF MICROSATELLITE INSTABILITY IN OESOGASTRIC ADENOCARCINOMA, NORDICAP 16-01.

  2021cites this paper
• Immuno-Interception for Patients with High-Risk Cancer

  2020cites this paper
• ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic therapy

  2020cites this paper
• Prognostic and predictive role of DNA mismatch repair status in stage II‐III colorectal cancer: A systematic review and meta‐analysis

  2020cites this paper
• Tumors: Colorectal

  2020cites this paper
• Colorectal Cancer in Older Adults: Systemic Treatments

  2020cites this paper
• Adjuvant Chemotherapy in Elderly Colorectal Cancer Patients

  2020cites this paper
• Treatment guidelines of metastatic colorectal cancer in older patients from the French Society of Geriatric Oncology (SoFOG).

  2020cites this paper
• Gastrointestinale Tumoren beim älteren und alten Patienten

  2020cites this paper
• Adénocarcinome de l’intestin grêle

  2019cites this paper
• Microsatellite Instability and Survival in Stage II Colorectal Cancer: A Systematic Review and Meta-analysis

  2019cites this paper
• Colorektales Karzinom – Besondere Aspekte in der Versorgung alter und geriatrischer Patienten

  2018cites this paper
• Treatment of Elderly Patients with Colorectal Cancer

  2018cites this paper
• Prognostic Value of Mismatch Repair Genes for Patients With Colorectal Cancer: Meta-Analysis

  2018influential citation
• Cancer du côlon non métastatique : désescalade thérapeutique

  2018cites this paper
• Prise en charge du cancer du côlon après résection curative

  2018cites this paper
• Etude du récepteur d’endocytose LRP1 dans les adénocarcinomes coliques : caractéristiques cliniques, pathologiques et moléculaires associées et valeur pronostique

  2017cites this paper
• Effect of Adjuvant Chemotherapy on Elderly Colorectal Cancer Patients: Lack of Evidence

  2017cites this paper
• Spécificités et valeur pronostique des N1c dans le cancer colorectal : une étude bi centrique sur 1122 cancers opérés entre 2011 et 2014

  2017cites this paper
• Prognostic survival associated with left-sided vs. right-sided Colon cancer: a systematic review and meta-analysis Petrelli F, et al (2017) JAMA Oncol 3:211–9

  2017cites this paper
• Colorectal cancer care in elderly patients: Unsolved issues.

  2016cites this paper
• PRODIGE 34-FFCD 1402-ADAGE: Adjuvant chemotherapy in elderly patients with resected stage III colon cancer: A randomized phase 3 trial.

  2016cites this paper
• Small Bowel Adenocarcinoma.

  2016cites this paper
• Le système immunitaire dans la carcinogenèse colorectale : ami ou ennemi ?

  2015cites this paper
• Analyse poolée de la chimiothérapie adjuvante après colectomie pour cancer chez le sujet âgé

  2015cites this paper
• Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer

  2015cites this paper
• Quoi de neuf pour l’adénocarcinome colorectal depuis la fin du dernier millénaire ?

  2015cites this paper
• Human mutL homolog 1 expression characteristic and prognostic effect on patients with sporadic colorectal cancer.

  2015cites this paper
• PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

  2015cites this paper
• PD-1 blockade in tumors with mismatch-repair deficiency

  2015cites this paper
• Oncogériatrie : cancers digestifs des patients âgés

  2014cites this paper
• Management of patients over 80 years of age treated with resection for localised colon cancer: results from a French referral centre.

  2014cites this paper
• Refining the chemotherapy approach for older patients with colon cancer.

  2014cites this paper
• Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.

  2014cites this paper
• Relationship between Aberrant Expression of hMSH 2 and Prognosis in Patients with Sporadic Colorectal Cancer

  2014cites this paper
• High prevalence of deficient mismatch repair phenotype and the V600E BRAF mutation in elderly patients with colorectal cancer.

  2014cites this paper
• Prise en charge des cancers du côlon non métastatique chez les patients âgés

  2013cites this paper
• L’instabilité microsatellite tumorale est un facteur prédictif du bénéfice d’une chimiothérapie adjuvante par 5 fluorouracile après résection d’un cancer du côlon

  2013cites this paper
• Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study

  2013influential citation