8p deletion is strongly linked to poor prognosis in breast cancer

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Cancer Biology & Therapy

• Publication date

  2015-05-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/15384047.2015.1046025PMID 25961141PMCID PMC4623106
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007cited by this paper
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  2005cited by this paper
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  2004influential reference
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancers

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1993cited by this paper
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  1991cited by this paper
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  1988cited by this paper
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  1982cited by this paper
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  1977cited by this paper

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