New anti-inflammatory N-pyridinyl(alkyl)phthalimides acting as tumour necrosis factor-alpha production inhibitors.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  European journal of medicinal chemistry

• Publication date

  2001-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0223-5234(01)01254-5PMID 11600233
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease.

  1999cited by this paper
• Tumour necrosis factor α and interleukin 1β in relapse of Crohn's disease

  1999cited by this paper
• 6-Amino-2,4-lutidine carboxamides: α-aminoamide derivatives as systemic and topical inflammation inhibitors

  1998cited by this paper
• Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity.

  1996cited by this paper
• Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides.

  1996cited by this paper
• Augmentation by phthalimides of phorbol ester-induced expression of tumor necrosis factor alpha message.

  1996cited by this paper
• New antiinflammatory compounds that inhibit tumor necrosis factor production: probable interaction with protein kinase C activation.

  1995cited by this paper
• Brain Injury and Inflammation. A Putative Role of TNFα

  1995cited by this paper
• Tumor necrosis factor, other cytokines and disease.

  1993cited by this paper
• Pharmacology of the skin

  1992cited by this paper
• Temporal infiltration of leukocyte subsets into mouse skin inflamed with phorbol ester

  1992cited by this paper
• Tumor Necrosis Factor: The molecules and Their Emerging Role in Medicine

  1992cited by this paper
• Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

  1991cited by this paper
• Hapten-induced model of chronic inflammation and ulceration in the rat colon.

  1989cited by this paper
• A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes.

  1986cited by this paper
• SYNTHESIS OF (4R)‐D,L‐(4‐2H)‐ AND (4S)‐D,L‐(42H)HOMOSERINE LACTONES

  1985cited by this paper
• Ibuproxam and ibuprofen. A pharmacological comparison.

  1977cited by this paper
• An endotoxin-induced serum factor that causes necrosis of tumors.

  1975cited by this paper
• Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

  1962cited by this paper
• α-Oxygenated Pyridines. III. The Reaction of N-Bromosuccinimide with Some Pyridine Derivatives1

  1952cited by this paper

• Phthalimides as anti-inflammatory agents.

  2024cites this paper
• Structure-Activity Relationship of 5-butyl-4,6-dimethyl-2-{[4-(o-fluorophenyl)-1-piperazinyl]-2-oxoethyl}-pyrrolo[3,4-c]pyrrole-1,3(2H,5H)-dione: an experimental and theoretical study

  2024cites this paper
• Synthesis, spectra, electronic structure, molecular docking and cytotoxicity investigation on 2-(piperidin-1-ylmethyl)-isoindoline-1,3-dione – A Mannich base system

  2021cites this paper
• Design and Synthesis of N-Substituted 3,4-Pyrroledicarboximides as Potential Anti-Inflammatory Agents

  2021cites this paper
• Biginelli Synthesis of Novel Dihydropyrimidinone Derivatives Containing Phthalimide Moiety

  2020cites this paper
• Enhancing insulin sensitivity by dual PPARγ partial agonist, β-catenin inhibitor: Design, synthesis of new αphthalimido-o-toluoyl2-aminothiazole hybrids.

  2020cites this paper
• Novel Heterocyclic Hybrids Based on 2-Pyrazoline: Synthesis and Assessment of Anti-Inflammatory and Analgesic Activities.

  2019cites this paper
• Investigation of DNA binding and molecular docking propensity of phthalimide derivatives: in vitro antibacterial and antioxidant assay

  2019cites this paper
• Selective formation of phthalimides from amines, aldehydes and CO by Pd-catalyzed oxidative C–H aminocarbonylation

  2018cites this paper
• Synthesis, docking and anticancer activity of azo-linked hybrids of 1,3,4-thia-/oxadiazoles with cyclic imides

  2018cites this paper
• Experimental and Theoretical Thermochemistry of the Isomers 3- and 4-Nitrophthalimide.

  2017cites this paper
• Solvent free, catalyst free, microwave or grinding assisted synthesis of bis-cyclic imide derivatives and their evaluation for anticancer activity.

  2017cites this paper
• Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library.

  2017cites this paper
• Synthesis, characterization, molecular modeling, and potential antimicrobial and anticancer activities of novel 2-aminoisoindoline-1,3-dione derivatives.

  2016cites this paper
• Synthesis of N-substituted phthalimides and their antifungal activity against Alternaria solani and Botrytis cinerea.

  2016cites this paper
• Phthalimide‐Derived N‐Benzylpyridinium Halides Targeting Cholinesterases: Synthesis and Bioactivity of New Potential Anti‐Alzheimer's Disease Agents

  2016cites this paper
• Discovery of novel phthalimide analogs: Synthesis, antimicrobial and antitubercular screening with molecular docking studies

  2016cites this paper
• Transition-Metal-Catalyzed Direct Addition of Aryl C-H Bonds to Unsaturated Electrophiles.

  2016cites this paper
• Synthesis and Carbonic Anhydrase Inhibition of Novel 2‐(4‐(Aryl)thiazole‐2‐yl)‐3a,4,7,7a‐tetrahydro‐1H‐4,7‐methanoisoindole‐1,3(2H)‐dione Derivatives

  2016cites this paper
• Beyond nutrition: hunger and its impact on the health of young Canadians

  2015cites this paper
• High Anti-Inflammatory Activity and Low Toxicity of Thalidomide Analogs

  2015cites this paper
• Ruthenium(II)-catalyzed C-H activation with isocyanates: a versatile route to phthalimides.

  2014cites this paper
• A Rhodium‐Catalyzed Cascade Cyclization: Direct Synthesis of N‐Substituted Phthalimides from Isocyanates and Benzoic Acids

  2014cites this paper
• Synthesis, hypolipidemic, and anti-inflammatory activities of arylphthalimides

  2014cites this paper
• Efficient palladium-catalyzed double carbonylation of o-dibromobenzenes: synthesis of thalidomide.

  2014cites this paper
• Synthesis and Antibacterial Evaluation of Carboxamide Derivatives of Amino Acids

  2014cites this paper
• The Construction of Polysubstituted Aromatic Core Derivatives via a Cycloaddition/Oxidative Aromatization Sequence from Quinone and β‐Enamino Esters

  2014cites this paper
• Synthesis, anti-inflammatory, and antiproliferative activity evaluation of isoindole, pyrrolopyrazine, benzimidazoisoindole, and benzimidazopyrrolopyrazine derivatives

  2013cites this paper
• Synthesis, Evaluation Antimicrobial Activity of Some New N-substituted Naphthalimides Containing Different Heterocyclic Rings

  2013cites this paper
• Synthesis, molecular modeling study, preliminary antibacterial, and antitumor evaluation of N-substituted naphthalimides and their structural analogues

  2013cites this paper
• QSAR STUDIES OF PHTHALIMIDE DERIVATIVES FOR THEIR POTENT ANXIOLYTIC ACTIVITY

  2012cites this paper
• Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response

  2012cites this paper
• Eco-friendly Synthesis of Phthalimide Derivatives, their Analgesic Activity and QSAR Studies

  2012cites this paper
• One-pot cascade leading to direct α-imidation of ketones by a combination of N-bromosuccinimide and 1,8-diazabicyclo[5.4.1]undec-7-ene.

  2012cites this paper
• Synthesis and cross-coupling reactions of imidomethyltrifluoroborates with aryl chlorides.

  2012cites this paper
• Palladium on Carbon: An Efficient, Heterogeneous and Reusable Catalytic System for Carbonylative Synthesis of N-Substituted Phthalimides

  2011cites this paper
• Synthesis, Anti‐inflammatory and Analgesic Evaluation of Certain New 3a,4,9,9a‐Tetrahydro‐4,9‐benzenobenz[f]isoindole‐1,3‐diones

  2011cites this paper
• SÍNTESE DE PRÓ-FÁRMACO RECÍPROCO COM POTENCIAL ATIVIDADE ANTI-PSORÍASE

  2011cites this paper
• A convergent synthesis of the imidazopyridine scaffold of fluorescent alkaloid ageladine A

  2011cites this paper
• 2,4,6-Trichloro-1,3,5-triazine/dimethylformamide as an efficient reagent for one-pot conversion of alcohols into N-alkylphthalimides

  2010cites this paper
• Colorimetric detection of achiral anions and chiral carboxylates by a chiral thiourea—phthalimide dyad

  2010cites this paper
• Palladium-catalyzed double carbonylation reactions of o-dihaloarenes with amines in phosphonium salt ionic liquids.

  2010cites this paper
• DESIGN AND ANTIINFLAMATORY ACTIVITY OF SOME NOVEL OXADIAZOLE DERIVATIVES – AN OVERVIEW

  2010cites this paper
• 2-[N-(2,4-Difluorophenyl)carbamoyl]-3,4,5,6-tetrafluorobenzoic acid

  2009cites this paper
• Syntheses, structural studies and spectroscopic characterisation of pyridyl-phthalimide complexes of fac-(CO)3ReI-diimines

  2009cites this paper
• The coordination chemistry of fluorescent pyridinyl- and quinolinyl-phthalimide ligands with the {Au(I)-PPh(3)} cationic unit.

  2009cites this paper
• Microwave-assisted synthesis of N-substituted cyclic imides and their evaluation for anticancer and anti-inflammatory activities.

  2009cites this paper
• Synthesis of some heterocyclic imides and azomethine derivatives under solvent free condition and their anti-inflammatory activity evaluation

  2009cites this paper
• N-Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic inflammation inhibitors.

  2008cites this paper
• An expedient chemo-enzymatic method for the synthesis of optically active masked 1,2-amino alcohols

  2008cites this paper
• N‐Alkylation of imides using phase transfer catalysts under solvent‐free conditions

  2008cites this paper
• N-Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic inflammation inhibitors

  2008cites this paper
• Rapid and clean synthesis of phthalimide derivatives in high-temperature, high-pressure H2O/EtOH mixtures

  2007cites this paper
• Thalidomide analogs from diamines: Synthesis and evaluation as inhibitors of TNF-alpha production.

  2007cites this paper
• Preparation of phthalamic acid derivatives and ring closure to phthalimidobarbituric acids

  2007cites this paper
• Thalidomide Analogs from Diamines: Synthesis and Evaluation as Inhibitors of TNF-α Production

  2007cites this paper
• N-(p-Methoxy­phenyl­sulfan­yl)phthalimide

  2007cites this paper
• 4,5,6,7-Tetrafluoro-2-(2-hydroxyphenyl)isoindoline-1,3-dione

  2007cites this paper
• Thalidomide analogues as anticancer drugs.

  2007cites this paper
• Synthesis, structural and conformational study of selected N-substituted phthalimides

  2005cites this paper
• Nonsteroidal anti-inflammatory drugs (NSAIDs): a comparative QSAR study.

  2005cites this paper
• Synthesis of 3-aryl-5-decapentyl-1,2,4-oxadiazoles possessing antiinflammatory and antitumor properties.

  2005cites this paper
• New N-pyridinyl(methyl)-indolalkanamides acting as topical inflammation inhibitors.

  2004cites this paper
• 1-(2,4-Di­chloro­phenyl)-2-phthalimidoethano­ne

  2004cites this paper
• Synthesis and anticancer activity of 5'-phthaloylnucleosides.

  2003cites this paper
• Antiangiogenic activity of N-substituted and tetrafluorinated thalidomide analogues.

  2003cites this paper
• New N-Pyridinyl(methyl)-N1-substituted-3-indolepropanamides Acting as Topical and Systemic Anti-inflammatory Agents

  2003cites this paper
• Microwave-assisted solid-phase synthesis of phthalimides.

  2003cites this paper
• New Antiinflammatory N‐Pyridinyl(alkyl)phthalimides Acting as Tumor Necrosis Factor‐α Production Inhibitors.

  2002cites this paper
• New N -pyridinyl(methyl)-indole-2- and 3-(Alkyl)carboxamides and Derivatives Acting as Systemic and Topical Inflammation Inhibitors

  2002cites this paper