Changes in cell surface glycosylation in alpha1,3-galactosyltransferase knockout and alpha1,2-fucosyltransferase transgenic mice.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Transplantation

• Publication date

  1997-07-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00007890-199707270-00003PMID 9256173
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Additive effects of CD59 expression in Gal knockout mice in vitro but not in an ex vivo model

  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation.

  1996cited by this paper
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  1996cited by this paper
• Anti-carbohydrate antibodies associated with hyperacute rejection in a vascularized mouse heart-to-rat xenotransplantation model.

  1996cited by this paper
• トランスジェニックマウスおよびトランスジェニックブタにおけるα(1,2)フコシルトランスフェラーゼの発現によるGal(α1,3)Galのレベルの低下

  1996cited by this paper
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  1996cited by this paper
• Alterations of cell surface carbohydrates and inhibition of metastatic property of murine melanomas by alpha 1,3 galactosyltransferase gene transfection.

  1995cited by this paper
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  1994cited by this paper
• Monomorphic and polymorphic carbohydrate antigens on pig tissues: implications for organ xenotransplantation in the pig‐to‐human model

  1994cited by this paper
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  1994cited by this paper
• Monomorphic and polymorphic carbohydrate antigens on pig tissues: implications for organ xenotransplantation in the pig-to-human model

  1994cited by this paper
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  1993cited by this paper
• CARBOHYDRATE ANTIGENS OF PIG TISSUES REACTING WITH HUMAN NATURAL ANTIBODIES AS POTENTIAL TARGETS FOR HYPERACUTE VASCULAR REJECTION IN PIG‐TO‐MAN ORGAN XENOTRANSPLANTATION1

  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Carbohydrate specificity of human immunoglobulin-M antibodies with pig lymphocytotoxic activity.

  1992cited by this paper
• Serological and immunochemical characterization of anti-PP1Pk (anti-Tja) antibodies in blood group little p individuals. Blood group A type 4 recognition due to internal binding.

  1992cited by this paper
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  1991cited by this paper
• Blood group type glycosphingolipids of human kidneys. Structural characterization of extended globo-series compounds

  1991cited by this paper
• Structural characterization of non-acid glycosphingolipids in kidneys of single blood group O and A pigs.

  1990cited by this paper
• Cold agglutination.

  1989cited by this paper
• Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.

  1988cited by this paper
• Red cell polyagglutination.

  1988cited by this paper
• Evolutionary relationship between the natural anti-Gal antibody and the Gal alpha 1----3Gal epitope in primates.

  1987cited by this paper
• Carbohydrate‐Specific Antibodies in Normal Human Sera

  1984cited by this paper
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  1984cited by this paper
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  1982cited by this paper
• Use of a synthetic hapten in the demonstration of the Thomsen-Friedenreich (T) antigen on neuraminidase-treated human red blood cells and lymphocytes.

  1981cited by this paper
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  1979cited by this paper
• Isoantigenic expression of Forssman glycolipid in human gastric and colonic mucosa: its possible identity with "A-like antigen" in human cancer.

  1977cited by this paper

• Mismatched Blood Types between Donors and Recipients Increase the Risk of BK Viremia One Year after Kidney Transplantation

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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
• Altered Glycosylation in Donor Mice Causes Rejection of Strain‐Matched Skin and Heart Grafts

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  2014cites this paper
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  2011cites this paper
• Genetic modification of pigs for solid organ xenotransplantation.

  2011cites this paper
• [Murine models in blood transfusion: allo-immunization, hemolysis].

  2011cites this paper
• Use of mouse models to study the mechanisms and consequences of RBC clearance

  2010cites this paper
• Distribution of the αGal‐ and the non‐αGal T‐antigens in the pig kidney: potential targets for rejection in pig‐to‐man xenotransplantation

  2008cites this paper
• Glycosylation changes in hFUT1 transgenic mice increase TCR signaling and apoptosis resulting in thymocyte maturation arrest.

  2008cites this paper
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  2008cites this paper
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  2007cites this paper
• The impact of the α1,3-galactosyltransferase gene knockout pig on xenotransplantation

  2007cites this paper
• The role of galactosyltransferases in cell surface functions and in the immune system.

  2006cites this paper
• The molecular basis for galalpha(1,3)gal expression in animals with a deletion of the alpha1,3galactosyltransferase gene.

  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2004cites this paper
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  2003cites this paper
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  2001cites this paper
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• Alternative Approaches to Reducing Gal Expression in Pig Organs

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  2001cites this paper
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  2001cites this paper
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  2000cites this paper
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  2000influential citation
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  2000cites this paper
• Hyperacute rejection of vascularized heart transplants in BALB/c Gal knockout mice

  2000cites this paper
• Immunobiology of Neural Xenotransplantation

  2000cites this paper
• Xenotransplantation: its problems and potential as a clinical procedure

  2000cites this paper
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  2000cites this paper
• Natural anti-carbohydrate IgM in mice: dependence on age and strain.

  2000cites this paper
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  1999cites this paper
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  1999cites this paper
• [Xenotransplantation. Possibilities of animal breeding].

  1999cites this paper
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  1999cites this paper
• IG-therasorb immunoapheresis in orthotopic xenotransplantation of baboons with landrace pig hearts.

  1999cites this paper
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  1999cites this paper
• Physiologic incompatibilities in discordant xenotransplantation.

  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
• Heterogeneous expression of Gal alpha1-3Gal xenoantigen in pig kidney: a lectin and immunogold electron microscopic study.

  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
• Current and future prospects for xenotransplantation.

  1998cites this paper
• Glycoproteins and Their Relationship to Human Disease

  1998cites this paper
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  1997cites this paper
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  1997cites this paper