The Role of Mitochondria in the Radiation-Induced Bystander Effect in Human Lymphoblastoid Cells

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Radiation Research

• Publication date

  2010-11-23

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1667/RR2296.1PMID 21268709
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mitochondrial Gene Expression Changes in Normal and Mitochondrial Mutant Cells after Exposure to Ionizing Radiation

  2010influential reference
• Involvement of MAPK proteins in bystander effects induced by chemicals and ionizing radiation.

  2010cited by this paper
• Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects.

  2009cited by this paper
• Influence of the bystander phenomenon on the chromosome aberration pattern in human lymphocytes induced by in vitro α-particle exposure

  2009cited by this paper
• Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect

  2009cited by this paper
• Radiation-induced bystander signalling in cancer therapy

  2009cited by this paper
• Bystander Effects Induced by Diffusing Mediators after Photodynamic Stress

  2009cited by this paper
• Recent insights into the biological action of heavy-ion radiation.

  2009cited by this paper
• Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial dysfunction.

  2009cited by this paper
• Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects.

  2009cited by this paper
• The radiobiology/radiation protection interface in healthcare

  2009cited by this paper
• Chemical induction of the bystander effect in normal human lymphoblastoid cells.

  2009cited by this paper
• Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects

  2008cited by this paper
• Bystander signal production and response are independent processes which are cell line dependent

  2008cited by this paper
• Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiation-induced bystander effects.

  2008cited by this paper
• Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells.

  2007influential reference
• Apoptosis: A Review of Programmed Cell Death

  2007cited by this paper
• Increased Mitochondrial Mass in Cells with Functionally Compromised Mitochondria after Exposure to both Direct γ Radiation and Bystander Factors

  2007cited by this paper
• Radiation induced bystander signals are independent of DNA damage and DNA repair capacity of the irradiated cells.

  2007cited by this paper
• Origin of mitochondria by intracellular enslavement of a photosynthetic purple bacterium

  2006cited by this paper
• Mechanisms of eukaryotic DNA double strand break repair.

  2006cited by this paper
• Role of Homologous Recombination in the Alpha-Particle-Induced Bystander Effect for Sister Chromatid Exchanges and Chromosomal Aberrations

  2005cited by this paper
• Chromosomal abnormalities in lymphocytes of children and baby rabbits born from mothers treated by X-irradiation before pregnancy. A transplacentary plasmatic chromosome-Damaged factor?

  2005cited by this paper
• UV induced bystander signaling leading to apoptosis.

  2005cited by this paper
• Oxidative Stress‐Induced Depolymerization of Microtubules and Alteration of Mitochondrial Mass in Human Cells

  2005cited by this paper
• Medium from Irradiated Cells Induces Dose-Dependent Mitochondrial Changes and BCL2 Responses in Unirradiated Human Keratinocytes

  2005cited by this paper
• Leber Hereditary Optic Neuropathy in 2 of 4 Siblings with 11778 mtDNA Mutation: Clinical Variability or Effect of Toxic Environmental Exposure?

  2004cited by this paper
• Mitochondrial DNA and aging.

  2004cited by this paper
• Evidence for induction of DNA double strand breaks in the bystander response to targeted soft X-rays in CHO cells.

  2004cited by this paper
• Radiation-induced bystander effects — implications for cancer

  2004cited by this paper
• Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation.

  2004cited by this paper
• Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

  2004cited by this paper
• Radiation-induced bystander effects, carcinogenesis and models

  2003cited by this paper
• HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures.

  2003cited by this paper
• MAPK pathways in radiation responses

  2003cited by this paper
• Persistent oxidative stress in chromosomally unstable cells.

  2003cited by this paper
• On the origin of mitochondria: a genomics perspective.

  2003cited by this paper
• Initiation of Apoptosis in Cells Exposed to Medium from the Progeny of Irradiated Cells: A Possible Mechanism for Bystander-Induced Genomic Instability?

  2002cited by this paper
• Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen.

  2001cited by this paper
• Radiation-Induced Bystander Effects: Past History and Future Directions

  2001cited by this paper
• Individual variation in the production of a 'bystander signal' following irradiation of primary cultures of normal human urothelium.

  2001cited by this paper
• Involvement of energy metabolism in the production of ‘bystander effects’ by radiation

  2000influential reference
• High and low fluences of alpha-particles induce a G1 checkpoint in human diploid fibroblasts.

  2000cited by this paper
• Factors underlying the cell growth-related bystander responses to alpha particles.

  2000cited by this paper
• High and Low Fluences of α-Particles Induce a G1 Checkpoint in Human Diploid Fibroblasts

  2000cited by this paper
• Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis

  2000cited by this paper
• Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells.

  1999cited by this paper
• Biochemical and molecular consequences of ethidium bromide treatment on Drosophila cells.

  1999cited by this paper
• Mitochondria in Neurodegeneration: Acute Ischemia and Chronic Neurodegenerative Diseases

  1999cited by this paper
• Chromosomal instability in the descendants of unirradiated surviving cells after alpha-particle irradiation.

  1998cited by this paper
• Testing for contributions of mitochondrial DNA mutations to complex diseases

  1998cited by this paper
• Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium.

  1998cited by this paper
• Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53

  1998cited by this paper
• Getting to the nucleus of mitochondrial disorders: identification of respiratory chain-enzyme genes causing Leigh syndrome.

  1998cited by this paper
• Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles.

  1998cited by this paper
• Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells.

  1997cited by this paper
• Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment.

  1997cited by this paper
• Catalytic activity of complex I in cell lines that possess replacement mutations in the ND genes in Leber's hereditary optic neuropathy.

  1996cited by this paper
• Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis.

  1994cited by this paper
• Epigenetic nature of radiation carcinogenesis at low doses.

  1994cited by this paper
• Leber's hereditary optic neuropathy: a model for mitochondrial neurodegenerative diseases

  1992cited by this paper
• Identification of aneuploidy‐inducing agents using cytokinesis‐blocked human lymphocytes and an antikinetochore antibody

  1989influential reference
• Measurement of micronuclei in lymphocytes.

  1985cited by this paper
• Radiation-induced clastogenic plasma factors.

  1984cited by this paper
• Chromosome aberrations in normal leukocytes induced by the plasma of exposed individuals.

  1977cited by this paper
• Chromosome Damage Induced by Plasma of X-Rayed Patients

  1968cited by this paper
• Cancer Epidemiology: Methods of Study

  1968cited by this paper
• Carcinogenesis

  1961cited by this paper
• Changes in sternal marrow following roentgen‐ray therapy to the spleen in chronic granulocytic leukemia

  1954cited by this paper

• Radiation Without Borders: Unraveling Bystander and Non-Targeted Effects in Oncology

  2025cites this paper
• Investigation of the effect of yeast NADH dehydrogenase (NDI1) on the radiation-induced bystander response in HCT116 cells with wild-type p53 function

  2025cites this paper
• Factors Influencing Effects of Low-dose Radiation Exposure.

  2024cites this paper
• Role of damaged mitochondrial transfer in alpha-particle generator 212Pb radiation-induced bystander effect

  2024cites this paper
• Biophoton signaling in mediation of cell-to-cell communication and radiation-induced bystander effects

  2024cites this paper
• Low-Dose Non-Targeted Effects and Mitochondrial Control

  2023cites this paper
• Hypothesis: can transfer of primary neoplasm-derived extracellular vesicles and mitochondria contribute to the development of donor cell-derived hematologic neoplasms after allogeneic hematopoietic cell transplantation?

  2022cites this paper
• Mitochondria - Nucleus communication in neurodegenerative disease. Who talks first, who talks louder?

  2022cites this paper
• A Mathematical Radiobiological Model (MRM) to Predict Complex DNA Damage and Cell Survival for Ionizing Particle Radiations of Varying Quality

  2021cites this paper
• Protection of melatonin against long‐term radon exposure‐caused lung injury

  2020cites this paper
• The mechanism of bystander effect induced by different irradiation in human neuroblastoma cells

  2020cites this paper
• Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model

  2020cites this paper
• Targeting of cellular redox metabolism for mitigation of radiation injury.

  2020cites this paper
• BIOPHOTONS IN RADIOBIOLOGY: INHIBITORS, COMMUNICATORS AND REACTORS.

  2019cites this paper
• Track-structure simulations of energy deposition patterns to mitochondria and damage to their DNA

  2019influential citation
• Mechanisms of Energy Metabolism in Skeletal Muscle Mitochondria Following Radiation Exposure

  2019cites this paper
• The Radiation-Induced Bystander Effect (RIBE) and its Connections with the Hallmarks of Cancer

  2019cites this paper
• Radiation-induced Non-targeted Effect and Carcinogenesis; Implications in Clinical Radiotherapy

  2018cites this paper
• The role of mitochondria in the non-targeted effect of ionizing radiation

  2018cites this paper
• Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?

  2017cites this paper
• Radiation interactions with biological systems

  2017cites this paper
• Analysis of the mechanism of radiation-induced upregulation of mitochondrial abundance in mouse fibroblasts

  2016cites this paper
• Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects.

  2015cites this paper
• Non-targeted effects induced by ionizing radiation: mechanisms and potential impact on radiation induced health effects.

  2015cites this paper
• Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation

  2015cites this paper
• Neutron Exposures in Human Cells: Bystander Effect and Relative Biological Effectiveness

  2014cites this paper
• Bystander Effects Due To Neutrons, And Low-Dose Hyper-Radiosensitivity To Gamma Rays In Human Cells Using Cytogenetics

  2014cites this paper
• Redox-Modulated Phenomena and Radiation Therapy: The Central Role of Superoxide Dismutases

  2014cites this paper
• Effects of ionizing radiation on mitochondria.

  2013cites this paper
• Relationships among micronuclei, nucleoplasmic bridges and nuclear buds within individual cells in the cytokinesis-block micronucleus assay.

  2013cites this paper
• Non-targeted effects induced by ionizing radiation : Mechanisms and potential impact on radiation induced health effects

  2013influential citation
• Estimating the Lowest Detectable Dose of Ionizing Radiation by the Cytokinesis-Block Micronucleus Assay

  2013cites this paper
• Near‐Infrared Exposure Changes Cellular Responses to Ionizing Radiation

  2012cites this paper
• Role of Reactive Oxygen Species and Nitric Oxide in Mediating Chemotherapeutic Drug Induced Bystander Response in Human Cancer Cells Exposed In-Vitro

  2012cites this paper
• Conditioned medium from actinomycin D-treated apoptotic cells induces mitochondria-dependent apoptosis in bystander cells.

  2012cites this paper
• Bystander apoptosis in human cells mediated by irradiated blood plasma.

  2012cites this paper
• Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury.

  2012cites this paper
• Analysis of the common deletions in the mitochondrial DNA is a sensitive biomarker detecting direct and non-targeted cellular effects of low dose ionizing radiation.

  2011cites this paper