Low plasma free choline is prevalent in patients receiving long term parenteral nutrition and is associated with hepatic aminotransferase abnormalities.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Clinical Nutrition

• Publication date

  1993-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0261-5614(93)90143-RPMID 16843274
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Liver function tests in patients receiving parenteral nutrition.

  1991cited by this paper
• Abnormal liver function in malnourished patients receiving total parenteral nutrition: a prospective randomized study.

  1990cited by this paper
• The natural history of nonalcoholic steatohepatitis: A follow‐up study of forty‐two patients for up to 21 years

  1990cited by this paper
• Plasma Amino Acid Concentrations in Children Receiving Long‐Term Parenteral Nutrition

  1988cited by this paper
• Hepatic complications of total parenteral nutrition.

  1987cited by this paper
• Intravenous nutrition and hepatic dysfunction.

  1986cited by this paper
• Plasma choline concentration in humans fed parenterally.

  1986cited by this paper
• Taurine concentrations in plasma and blood cells of patients undergoing long-term parenteral nutrition.

  1986cited by this paper
• Plasma concentrations of transsulfuration pathway products during nasoenteral and intravenous hyperalimentation of malnourished patients.

  1985cited by this paper
• Similar liver function abnormalities occur in patients receiving glucose-based and lipid-based parenteral nutrition.

  1983cited by this paper
• Morphological fatty changes and function of the liver, serum free fatty acids, and triglycerides during parenteral nutrition.

  1982cited by this paper
• Choline deficiency associated with total parenteral nutrition.

  1980cited by this paper
• The effect of hyperalimentation on hepatic lipid content and lipogenic enzyme activity in rats and man.

  1980cited by this paper
• Clinical and biological changes in liver function during intravenous hyperalimentation.

  1979cited by this paper
• Choline and phospholipid metabolism and the synthesis of acetylcholine in rat brain

  1979cited by this paper
• Liver function values in adults receiving total parenteral nutrition.

  1979cited by this paper
• Hepatic dysfunction during hyperalimentation.

  1978cited by this paper
• The relationship of choline and carnitine in the choline deficient rat.

  1978cited by this paper
• Serum hepatic enzyme and bilirubin elevations during parenteral nutrition.

  1977cited by this paper
• Total parenteral nutrition at home: studies in patients surviving 4 months to 5 years.

  1976cited by this paper
• PLASMA CHOLINE: ITS TURNOVER AND EXCHANGE WITH BRAIN CHOLINE 1

  1975cited by this paper
• Relationship between hepatic morphology and clinical and biochemical findings in morbidly obese patients

  1973cited by this paper
• Simultaneous measurement of endogenous and deuterium-labeled tracer variants of choline and acetylcholine in subpicomole quantities by gas chromatography-mass spectrometry.

  1973cited by this paper
• Modern Nutrition in Health and Disease

  1965cited by this paper
• A simple method for the isolation and purification of total lipides from animal tissues.

  1957cited by this paper

• Intestinal-Failure-Associated Liver Disease: Beyond Parenteral Nutrition

  2025cites this paper
• Relationship of choline intake with biomarkers of liver health by genotype - a cross-sectional analysis.

  2025cites this paper
• Intestinal failure-associated liver disease: Current challenges in screening, diagnosis, and parenteral nutrition considerations.

  2024cites this paper
• Factors that impact on the quality of life of intestinal failure patients treated with home parenteral nutrition: protocol for a multicentre, longitudinal observational study

  2024cites this paper
• Evidence and Perspectives for Choline Supplementation during Parenteral Nutrition—A Narrative Review

  2024influential citation
• Choline – a scoping review for Nordic Nutrition Recommendations 2023

  2023cites this paper
• The central role of the gut in intensive care

  2022cites this paper
• Parenteral Nutrition

  2021cites this paper
• Choline deficiency: Is it being recognized?

  2021cites this paper
• New insights into intestinal failure–associated liver disease in adults: A comprehensive review of the literature

  2021cites this paper
• Impact of Parenteral Lipid Emulsion Components on Cholestatic Liver Disease in Neonates

  2021cites this paper
• Formulation guidelines for infant formula

  2021cites this paper
• Review of parenteral nutrition-associated liver disease

  2020cites this paper
• Serum choline in extremely preterm infants declines with increasing parenteral nutrition

  2020cites this paper
• Dietary Choline Intake: Current State of Knowledge Across the Life Cycle

  2018cites this paper
• The Differentiation of Intestinal-Failure-Associated Liver Disease from Nonalcoholic Fatty Liver and Nonalcoholic Steatohepatitis

  2017cites this paper
• Supplementary choline attenuates olive oil lipid emulsion‐induced enterocyte apoptosis through suppression of CELF1/AIF pathway

  2017cites this paper
• Dietary choline intake and biomarkers of choline status across the life cycle

  2017influential citation
• Nutritional Risk Factors in the Pathogenesis of Parenteral Nutrition-Associated Liver Disease

  2017cites this paper
• Parenteral Nutrition-associated Liver Disease

  2017cites this paper
• Metabolic Complications of Home Parenteral Nutrition

  2017cites this paper
• Australasian society for parenteral and enteral nutrition (AuSPEN) adult vitamin guidelines for parenteral nutrition.

  2016cites this paper
• Choline Protects Against Intestinal Failure–Associated Liver Disease in Parenteral Nutrition–Fed Immature Rats

  2016cites this paper
• The complexity of understanding human milk components and infant brain development

  2016cites this paper
• Dietary Reference Values for choline

  2016cites this paper
• Endoplasmic Reticulum Stress Is Implicated in Intestinal Failure-Associated Liver Disease.

  2016cites this paper
• Authorised EU health claims for choline

  2014cites this paper
• Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults.

  2012cites this paper
• A myriad of pathways to NASH.

  2012cites this paper
• Pathogenesis and treatment of parenteral nutrition-associated liver disease.

  2012cites this paper
• Oral Choline Supplementation in Children With Intestinal Failure

  2011cites this paper
• Hepatobiliary manifestations of gastrointestinal and nutritional disorders.

  2011cites this paper
• Olive oil-based fat emulsion versus soy oil-based fat emulsion in abdominal oncologic surgery.

  2011cites this paper
• Abnormal liver function tests in the parenteral nutrition fed patient

  2010cites this paper
• Nutrition Interventions Before and After Adult Intestinal Transplantation : The Pittsburgh Experience

  2010cites this paper
• Whole-blood–free Choline and Choline Metabolites in Infants Who Require Chronic Parenteral Nutrition Therapy

  2010influential citation
• Nutrition Interventions Before and After Adult Intestinal Transplantation: The Pittsburgh Experience

  2010cites this paper
• Choline.

  2010cites this paper
• The addition of choline to parenteral nutrition.

  2009cites this paper
• Effects of choline‐deprivation on paracetamol‐ or phenobarbital‐induced rat liver metabolic response

  2009cites this paper
• Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load 2,3

  2008cites this paper
• BAPEN Symposium 4 on 'Managing complications in long-term parenteral nutrition' : Managing liver dysfunction in parenteral nutrition

  2007cites this paper
• Hepatobiliary Complications of Parenteral Nutrition

  2007cites this paper
• Managing liver dysfunction in parenteral nutrition

  2007cites this paper
• Choline deficiency is associated with increased risk for venous catheter thrombosis.

  2006cites this paper
• Choline deficiency increases lymphocyte apoptosis and DNA damage in humans.

  2006cites this paper
• Parenteral nutrition-associated liver disease in adult and pediatric patients.

  2006cites this paper
• Choline: critical role during fetal development and dietary requirements in adults.

  2006cites this paper
• Total parenteral nutrition: challenges and practice in the cirrhotic patient.

  2006cites this paper
• Total parenteral nutrition-related gastroenterological complications.

  2006cites this paper
• Parenteral nutrition–associated liver disease and the role for isolated intestine and intestine/liver transplantation

  2006cites this paper
• Nutrient reference values for Australia and New Zealand: Including recommended dietary intakes

  2006cites this paper
• Relation between choline and carnitine homeostasis

  2005cites this paper
• Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.

  2005cites this paper
• PN-associated hepatobiliary and renal disease.

  2005cites this paper
• Complications of Long-Term Home Total Parenteral Nutrition

  2004cites this paper
• Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria.

  2004cites this paper
• Effect of total parenteral nutrition and choline on hepatic flavin-containing and cytochrome P-450 monooxygenase activity in rats.

  2004cites this paper
• Concentrations of choline-containing compounds and betaine in common foods.

  2003cites this paper
• Choline and vitamin B12 deficiencies are interrelated in folate-replete long-term total parenteral nutrition patients.

  2002cites this paper
• Total parenteral nutrition-associated liver disease.

  2002cites this paper
• Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults.

  2002cites this paper
• Changes of plasma free choline and choline-containing compounds' concentrations and choline loss during hemodialysis in ESRD patients.

  2002cites this paper
• Postoperative jaundice and total parenteral nutrition-associated hepatic dysfunction.

  2002cites this paper
• Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial.

  2001cites this paper
• Verbal and visual memory improve after choline supplementation in long-term total parenteral nutrition: a pilot study.

  2001cites this paper
• Nutritional and Metabolic Considerations in the Etiology of Nonalcoholic Steatohepatitis

  2001influential citation
• Plasma choline in normal newborns, infants, toddlers, and in very-low-birth-weight neonates requiring total parenteral nutrition.

  2001cites this paper
• Hyperhomocysteinemia is associated with venous thrombosis in patients with short bowel syndrome.

  2001cites this paper
• Choline: an essential nutrient for humans.

  2000cites this paper
• Changes in plasma free and phospholipid-bound choline concentrations in chronic hemodialysis patients.

  2000cites this paper
• Choline: Needed for Normal Development of Memory

  2000cites this paper
• Gut and nutrients

  1999cites this paper
• Plasma choline concentrations in children requiring long-term home parenteral nutrition: a case control study.

  1999cites this paper
• Choline and phosphatidylcholine are important components of an infants diet.

  1998cites this paper
• Choline deficiency selects for resistance to p53-independent apoptosis and causes tumorigenic transformation of rat hepatocytes.

  1997cites this paper
• Essential nature of choline with implications for total parenteral nutrition.

  1997cites this paper
• Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction.

  1997cites this paper
• Relation between choline and carnitine homeostasis.

  1997cites this paper
• Methyl‐group donors cannot prevent apoptotic death of rat hepatocytes induced by choline‐deficiency

  1996cites this paper
• Nutrients, signal transduction and carcinogenesis.

  1995cites this paper
• Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver.

  1995cites this paper
• Accelerated uptake of an intravenously administered dose of choline chloride in choline-deficient humans

  1994cites this paper
• Choline and human nutrition.

  1994cites this paper
• Choline Essential for Every Body

  year unknowncites this paper
• Choline An Essential Nutrient for Metabolism

  year unknowncites this paper