Interleukin-8 is essential for normal urothelial cell survival.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  AJP - Renal Physiology

• Publication date

  2009-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajprenal.90733.2008PMID 19535567PMCID PMC2739718
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Urine markers do not predict biopsy findings or presence of bladder ulcers in interstitial cystitis/painful bladder syndrome.

  2008cited by this paper
• The Interleukin-8 Pathway in Cancer

  2008cited by this paper
• HIF-1 and NF-κB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells

  2007cited by this paper
• Modulation of Host Innate Immune Response in the Bladder by Uropathogenic Escherichia coli

  2007cited by this paper
• Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer.

  2007cited by this paper
• Discovery of morphological subgroups that correlate with severity of symptoms in interstitial cystitis: a proposed biopsy classification system.

  2007cited by this paper
• A Genetic Basis of Susceptibility to Acute Pyelonephritis

  2007cited by this paper
• Uropathogenic Escherichia coli Induces Extrinsic and Intrinsic Cascades To Initiate Urothelial Apoptosis

  2006cited by this paper
• The Akt/PKB pathway: molecular target for cancer drug discovery

  2005cited by this paper
• Dysregulation of proinflammatory and regulatory cytokines in HIV infected persons with active tuberculosis.

  2005cited by this paper
• Helicobacter pylori-Stimulated Interleukin-8 (IL-8) Promotes Cell Proliferation Through Transactivation of Epidermal Growth Factor Receptor (EGFR) by Disintegrin and Metalloproteinase (ADAM) Activation

  2005cited by this paper
• Human CD8+ T cells store CXCR1 in a distinct intracellular compartment and up-regulate it rapidly to the cell surface upon activation.

  2005cited by this paper
• IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells.

  2005cited by this paper
• Expression of Interleukin-8 Receptors (CXCR1 and CXCR2) in Premenopausal Women with Recurrent Urinary Tract Infections

  2005cited by this paper
• Toll-Like Receptor 4 Expression and Cytokine Responses in the Human Urinary Tract Mucosa

  2004cited by this paper
• Interleukin-8/CXCL8 Forms an Autocrine Loop in Fetal Intestinal Mucosa

  2004cited by this paper
• IL-8 Directly Enhanced Endothelial Cell Survival, Proliferation, and Matrix Metalloproteinases Production and Regulated Angiogenesis1

  2003cited by this paper
• Intrinsic activation of PI3K/Akt signaling pathway and its neuroprotective effect against retinal injury

  2003cited by this paper
• Bladder permeability barrier: recovery from selective injury of surface epithelial cells.

  2002cited by this paper
• Multiple control of interleukin‐8 gene expression

  2002cited by this paper
• Molecular Regulation of Urothelial Renewal and Host Defenses during Infection with Uropathogenic Escherichia coli * 210

  2002cited by this paper
• A comparison of multiple urine markers for interstitial cystitis.

  2002cited by this paper
• Biopsy features are associated with primary symptoms in interstitial cystitis: results from the interstitial cystitis database study.

  2001cited by this paper
• Neutrophil recruitment, chemokine receptors, and resistance to mucosal infection

  2001cited by this paper
• The epidemiology of interstitial cystitis: is it time to expand our definition?

  2001cited by this paper
• Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway.

  2001cited by this paper
• New biologicals for prostate cancer prevention: Genes, vaccines, and immune-based interventions.

  2001cited by this paper
• Uropathogenic Escherichia coliPotentiates Type 1 Pilus-Induced Apoptosis by Suppressing NF-κB

  2001cited by this paper
• Interleukin-8 and human cancer biology.

  2001cited by this paper
• From the Cover: Bad bugs and beleaguered bladders: Interplay between uropathogenic Escherichia coli and innate host defenses

  2000cited by this paper
• The biology of chemokines and their receptors.

  2000cited by this paper
• Transepithelial Neutrophil Migration Is CXCR1 Dependent In Vitro and Is Defective in IL-8 Receptor Knockout Mice1

  2000cited by this paper
• Interleukin-8: an autocrine/paracrine growth factor for human hematopoietic progenitors acting in synergy with colony stimulating factor-1 to promote monocyte-macrophage growth and differentiation.

  1999cited by this paper
• Preliminary study on urinary cytokine levels in interstitial cystitis: does intravesical bacille Calmette-Guérin treat interstitial cystitis by altering the immune profile in the bladder?

  1999cited by this paper
• Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli.

  1998cited by this paper
• Cytokine repertoire of epithelial cells lining the human urinary tract.

  1998cited by this paper
• Chemokines.

  1997cited by this paper
• Human chemokines: an update.

  1997cited by this paper
• Role of the C Terminus of the Interleukin 8 Receptor in Signal Transduction and Internalization*

  1996cited by this paper
• IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor.

  1993cited by this paper
• Elevated interleukin-8 levels in the urine of patients with urinary tract infections

  1993cited by this paper
• Clinical features and spectrum of light microscopic changes in interstitial cystitis.

  1990cited by this paper
• Comparison of antigen expression on normal urothelial cells in tissue section and tissue culture.

  1990cited by this paper
• Tenascin mediates cell attachment through an RGD-dependent receptor

  1989cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper

• Cellular and Molecular Aspect of Bladder Pain Syndrome: An Entry Point to Exploration of Its Pathogenesis

  2024cites this paper
• The Laws of Attraction: Chemokines as Critical Mediators in Cancer Progression and Immunotherapy Response in Bladder Cancer

  2024cites this paper
• A Decision Tree Model Using Urine Inflammatory and Oxidative Stress Biomarkers for Predicting Lower Urinary Tract Dysfunction in Females

  2024cites this paper
• Estrogen-stimulated uropathogenic E. coli mediate enhanced neutrophil responses

  2024cites this paper
• Tumor microenvironment and epithelial-mesenchymal transition in bladder cancer: Cytokines in the game?

  2023cites this paper
• Effects of aging on urinary tract epithelial homeostasis and immunity.

  2022cites this paper
• Biomarkers in bladder pain syndrome: A new narrative

  2022cites this paper
• Can We Use Urinary Cytokine/Chemokine Analysis in Discriminating Ulcer-Type Interstitial Cystitis/Bladder Pain Syndrome?

  2022cites this paper
• S2k-Leitlinie Diagnostik und Therapie der interstitiellen Zystitis (IC/BPS)

  2022cites this paper
• Urinary Biomarkers in Interstitial Cystitis/Bladder Pain Syndrome and Its Impact on Therapeutic Outcome

  2021cites this paper
• Exploration of the core genes in ulcerative interstitial cystitis/bladder pain syndrome

  2021cites this paper
• [Interstitial cystitis/bladder pain syndrome (IC/BPS)].

  2020cites this paper
• Urine Cytokines as Biomarkers for Diagnosing Interstitial Cystitis/Bladder Pain Syndrome and Mapping Its Clinical Characteristics.

  2020cites this paper
• COMPARISON OF SERUM ACUTE PHASE PROTEINS AND INFLAMMATORY CYTOKINES BETWEEN HEALTHY AND SUBCLINICALLY ENDOMETRITIC POSTPARTUM BUFFALOES

  2020cites this paper
• S 2 K guideline Diagnosis and Treatment of Interstitial Cystitis ( IC / BPS )

  2019cites this paper
• Therapeutic potential of intravesical injections of platelet-rich plasma in the treatment of lower urinary tract disorders due to regenerative deficiency

  2019influential citation
• Repeated intravesical injections of platelet‐rich plasma are effective in the treatment of interstitial cystitis: a case control pilot study

  2019influential citation
• Identification of functional single nucleotide polymorphisms (SNPs) in High Risk-Human Papillomavirus (HR-HPV) related diseases

  2018cites this paper
• Neutrophils contribute to the pathogenesis of hemorrhagic cystitis induced by ifosfamide

  2018cites this paper
• Urothelial Cancer: Inflammatory Mediators and Implications for Immunotherapy

  2016cites this paper
• Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of Disease

  2016cites this paper
• Clinical guidelines for interstitial cystitis and hypersensitive bladder updated in 2015

  2016cites this paper
• Pathophysiology of interstitial cystitis/bladder pain syndrome

  2015cites this paper
• Relationship of Urothelial Gene Expressions in Urine-Deprived Bladders of Renal Recipients With Posttransplant Urinary Infections.

  2015cites this paper
• H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation

  2015cites this paper
• Proliferation of the human urothelium is induced by atypical β1 -adrenoceptors.

  2015cites this paper
• Hyaluronic acid decreases IL-6 and IL-8 secretion and permeability in an inflammatory model of interstitial cystitis.

  2015cites this paper
• Characterization of buffalo interleukin 8 (IL-8) and its expression in endometritis

  2015cites this paper
• Intravesical gemcitabine treatment: repercussions on normal bladder function.

  2015cites this paper
• Potential urine and serum biomarkers for patients with bladder pain syndrome/interstitial cystitis

  2014cites this paper
• Low Interleukin - 8 Level Predicts the Occurrence of the Postpericardiotomy Syndrome

  2014cites this paper
• Editorial Comment from Dr Hanno to Potential urine and serum biomarkers for patients with bladder pain syndrome/interstitial cystitis

  2014cites this paper
• Increased Pro-Inflammatory Cytokines, C-Reactive Protein and Nerve Growth Factor Expressions in Serum of Patients with Interstitial Cystitis/Bladder Pain Syndrome

  2013cites this paper
• Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres.

  2013cites this paper
• Interstitial cystitis/bladder pain syndrome: diagnosis and management

  2013cites this paper
• Characterization of a unique technique for culturing primary adult human epithelial progenitor/“stem cells”

  2012cites this paper
• Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells.

  2012cites this paper
• Pathogenic and Diagnostic Potential of BLCA-1 and BLCA-4 Nuclear Proteins in Urothelial Cell Carcinoma of Human Bladder

  2012cites this paper
• CXCR1 deficiency does not alter liver regeneration after partial hepatectomy in mice.

  2011cites this paper
• Tumor necrosis factor-α induces expression and release of interleukin-6 by human urothelial cells

  2011cites this paper