The anti-tumor activity of brown seaweed oligo-fucoidan via lncRNA expression modulation in HepG2 cells

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Cytotechnology (Dordrecht)

• Publication date

  2019-01-10

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s10616-019-00293-7PMID 30632031PMCID PMC6368498
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• LincRNA-p21 inhibits invasion and metastasis of hepatocellular carcinoma through miR-9/E-cadherin cascade signaling pathway molecular mechanism

  2017cited by this paper
• A mechanism of low molecular weight fucoidans degraded by enzymatic and acidic hydrolysis for the prevention of UVB damage

  2017cited by this paper
• Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells

  2017cited by this paper
• The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186

  2017cited by this paper
• Long non-coding RNA NEAT1 promotes hepatocellular carcinoma cell proliferation through the regulation of miR-129-5p-VCP-IκB.

  2017cited by this paper
• Combined administration of fucoidan ameliorates tumor and chemotherapy-induced skeletal muscle atrophy in bladder cancer-bearing mice

  2016cited by this paper
• Toxicological Evaluation of Low Molecular Weight Fucoidan in Vitro and in Vivo

  2016cited by this paper
• LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway

  2016cited by this paper
• Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis

  2016cited by this paper
• Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells

  2015cited by this paper
• Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43

  2015cited by this paper
• Long non-coding RNAs and hepatocellular carcinoma.

  2015cited by this paper
• LincRNA-p21 acts as a mediator of ING1b-induced apoptosis

  2015cited by this paper
• LincRNA-p21: Implications in Human Diseases

  2015cited by this paper
• Regulation of MicroRNAs by Natural Agents: New Strategies in Cancer Therapies

  2014cited by this paper
• Fucoidan Inhibits the Proliferation of Human Urinary Bladder Cancer T24 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis

  2014cited by this paper
• The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines

  2014cited by this paper
• FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphoma

  2014cited by this paper
• Fucoidan inhibition of lung cancer in vivo and in vitro: role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation

  2014cited by this paper
• Fucoidan Induces Cancer Cell Apoptosis by Modulating the Endoplasmic Reticulum Stress Cascades

  2014cited by this paper
• Fucoidan Derived from Undaria pinnatifida Induces Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells via the ROS-Mediated Mitochondrial Pathway

  2013cited by this paper
• Noncoding RNAs and cancer.

  2013cited by this paper
• Long Noncoding RNAs: Past, Present, and Future

  2013cited by this paper
• Non-Coding RNAs: Multi-Tasking Molecules in the Cell

  2013cited by this paper
• Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer.

  2013cited by this paper
• LncRNADisease: a database for long-non-coding RNA-associated diseases

  2012cited by this paper
• Inhibition of Lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells.

  2011cited by this paper
• Caspase-8 and bid: caught in the act between death receptors and mitochondria.

  2011cited by this paper
• Therapies from Fucoidan; Multifunctional Marine Polymers

  2011cited by this paper
• Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma.

  2010cited by this paper
• Relationship between Oversulfation and Conformation of Low and High Molecular Weight Fucoidans and Evaluation of Their in Vitro Anticancer Activity

  2010influential reference
• Effects of MicroRNA‐29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma

  2009cited by this paper
• Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin.

  2009influential reference
• Bid: a Bax-like BH3 protein

  2008cited by this paper
• Identification and characterization of a novel gene Saf transcribed from the opposite strand of Fas.

  2005cited by this paper
• Multidrug resistance gene (MDR‐1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection

  2001cited by this paper
• Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis

  1999influential reference
• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

  1995cited by this paper
• Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

  1995cited by this paper
• Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

  1994cited by this paper
• Incidence and factors associated with intrahepatic recurrence following resection of hepatocellular carcinoma.

  1993cited by this paper

• Recent advances in the antileukemic mechanisms of fucoidan based on epigenetic regulation (Review).

  2025cites this paper
• LincRNA-miR interactions in hepatocellular carcinoma: comprehensive review and in silico analysis: a step toward ncRNA precision

  2025cites this paper
• An in-depth evaluation of fucoidans from five brown seaweeds for wound healing and cytoprotection: analyses of bioactivities and cellular mechanisms.

  2025cites this paper
• Selenium nanoparticles decorated by fucoidan induce ferroptosis in HepG2 cells.

  2024cites this paper
• The structural characteristics, biological activities and mechanisms of bioactive brown seaweed polysaccharides: A review

  2024cites this paper
• Marine algal polysaccharides as future potential constituents against non-alcoholic steatohepatitis.

  2023cites this paper
• Anticancer potential of algae-derived metabolites: recent updates and breakthroughs

  2023cites this paper
• A sequential recovery extraction and biological activity of water-soluble sulfated polysaccharides from the polar red macroalgae Sarcopeltis skottsbergii

  2023cites this paper
• Efficacy and anti-inflammatory properties of low-molecular-weight fucoidan in patients with atopic dermatitis: a randomized double-blinded placebo-controlled trial

  2023cites this paper
• Prospects for the use of brown algae as a natural adaptogen

  2023cites this paper
• A Comprehensive Integrated Analysis of DDX3X Expression, Prognostic Value and Potential Implications for Pan-Cancer Immunity

  2023cites this paper
• Huashi Jiedu decoction blocks cell cycle and inhibits EMT of gastric cells via LncRNA-p21

  2023cites this paper
• Fucoidan-Mediated Inhibition of Fibrotic Properties in Oral Submucous Fibrosis via the MEG3/miR-181a/Egr1 Axis

  2022influential citation
• Effect of Extraction Temperature on Pressurized Liquid Extraction of Bioactive Compounds from Fucus vesiculosus

  2022cites this paper
• Oligo-Fucoidan supplementation enhances the effect of Olaparib on preventing metastasis and recurrence of triple-negative breast cancer in mice

  2022cites this paper
• [Fucoidan-Modified Phase-Transitional Contrast Agent for Ultrasound Imaging and Targeting of Hepatoma Cells].

  2022cites this paper
• Non-coding RNA-related antitumor mechanisms of marine-derived agents

  2022influential citation
• Exosomal lncRNA-p21 derived from mesenchymal stem cells protects epithelial cells during LPS-induced acute lung injury by sponging miR-181.

  2021cites this paper
• Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis.

  2021cites this paper
• Beneficial effects of seaweed-derived dietary fiber: Highlights of the sulfated polysaccharides.

  2021cites this paper
• Recent advances in industrial applications of seaweeds

  2021cites this paper
• Antitumoral effects of fucoidan on bladder cancer

  2020cites this paper
• Fucoidans : the importance of processing on its 1 anti-tumoral properties

  2020cites this paper
• Enzyme-Assisted Fucoidan Extraction from Brown Macroalgae Fucus distichus subsp. evanescens and Saccharina latissima

  2020cites this paper
• Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy.

  2020cites this paper
• Fucoidans: The importance of processing on their anti-tumoral properties

  2020cites this paper
• Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum

  2020cites this paper
• Seaweed components, properties, and applications

  2020cites this paper
• The molecular mechanisms of LncRNA-correlated PKM2 in cancer metabolism

  2019cites this paper
• Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds

  2019cites this paper
• Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling

  2017cites this paper