Secretion of somatostatin from the normal and diabetic pancreas

No abstract is available for this paper.

• Publication year

  1980

• Venue

  Diabetologia

• Publication date

  1980-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/BF00253175PMID 6109682
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pancreatic D-Cell Recognition of D-Glucose: Studies with D-Glucose, D-Glyceraldehyde, Dihydroxyacetone, D-Mannoheptulose, D-Fructose, D-Galactose, and D-Ribose

  1981cited by this paper
• Effects of substance P and other peptides on the release of somatostatin, insulin, and glucagon in vitro.

  1981cited by this paper
• Duodenal Contribution to Pancreaticoduodenal Vein Islet Hormones During Stimulation of the Canine Pancreas with Calcium

  1980cited by this paper
• Starvation-induced Changes of Somatostatin, Glucagon, and Insulin Secretion from the Isolated Perfused Rat Pancreas

  1980cited by this paper
• The role of sodium in somatostatin secretion: evidence for the involvement of Na+ channels in the release mechanism.

  1980cited by this paper
• Somatostatin Concentration Responds to Arginine in Portal Plasma: Effects of Fasting, Streptozotocin Diabetes, and Insulin Administration in Diabetic Rats

  1980cited by this paper
• Sustained oscillations of insulin, glucagon, and somatostatin from the isolated canine pancreas during exposure to a constant glucose concentration.

  1980cited by this paper
• Effects of Substance P and Other Peptides on the Release of Somatostatin, Insulin, and Glucagon in Vitro

  1980cited by this paper
• Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis.

  1980cited by this paper
• Neural regulation of pancreatic hormone secretion by the C-terminal tetrapeptide of CCK

  1980cited by this paper
• Insulin, glucagon, and somatostatin secretion from isolated perfused rat and chicken pancreas-duodenum.

  1980cited by this paper
• The effect of somatostatin on the hepatic extraction of insulin and glucagon in the anesthetized dog.

  1980cited by this paper
• The Significance of the Na+/K+ Pump for Somatostatin Release

  1980cited by this paper
• Sulphonylurea (glubenclamide) enhances somatostatin and inhibits glucagon release induced by arginine.

  1980cited by this paper
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  1979cited by this paper
• Neurotensin inhibits glucose but not glucagon-induced insulin and somatostatin release in isolated islets.

  1979cited by this paper
• Somatostatin: central nervous system actions on glucoregulation.

  1979cited by this paper
• Characterization of somatostatin release from the pancreas: the role of potassium.

  1979cited by this paper
• Intercellular communication in pancreatic islet monolayer cultures: a microfluorometric study.

  1979cited by this paper
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  1979cited by this paper
• Metabolic clearance and plasma half-disappearance time of exogenous somatostatin in man.

  1979cited by this paper
• Gastric and Pancreatic Release of Somatostatin-like Immunoreactivity During the Gastric Phase of a Meal: Effects of Truncal Vagotomy and Atropine in the Anesthetized Dog

  1979cited by this paper
• Streptozotocin diabetes: A glucoreceptor dysfunction affecting D cells as well as B and A cells

  1979cited by this paper
• Theophylline: Potentiation of Arginine-induced Somatostatin Release from the Isolated Rat Pancreas

  1979cited by this paper
• Peptidergic and adrenergic innervation of pancreatic ganglia.

  1979cited by this paper
• Isolation and characterization of somatostatin from pigeon pancreas.

  1979cited by this paper
• Evidence for a role of splanchnic somatostatin in the homeostasis of ingested nutrients.

  1979cited by this paper
• Tissue and Serum Somatostatin-like Immunoreactivity in Fed, 15-h-fasted, and 72-h-fasted Rats

  1979cited by this paper
• Characterisation of somatostatin release from the pancreas

  1979cited by this paper
• Somatostatin secretion from monolayer cultures of neonatal rat pancreas.

  1979cited by this paper
• Somatostatin analogs inhibit somatostatin release.

  1979cited by this paper
• Effect of Fasting on the Release of Insulin and Somatostatin from Perifused Islets of Langerhans

  1979cited by this paper
• Peptidergic and adrenergic innervation of pancreatic ganglia.

  1979cited by this paper
• Characteristics of the Dopaminergic and Noradrenergic Systems of the Pancreatic Islets

  1979cited by this paper
• Radioimmunoassay of somatostatin and its application in the study of pancreatic somatostatin secretion in vitro.

  1979cited by this paper
• Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas.

  1979cited by this paper
• Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas.

  1979cited by this paper
• Somatostatin Release from Isolated Perfused Rat Pancreas: Possible Role of Endogenous Somatostatin on Insulin Release

  1979cited by this paper
• Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas.

  1979cited by this paper
• Increased somatostatin release from pancreases of alloxan diabetic rats perfused in vitro.

  1979cited by this paper
• Insulin stimulates somatostatin and inhibits glucagon secretion from the perfused chicken pancreas-duodenum.

  1979cited by this paper
• Somatostatin cell processes as pathways for paracrine secretion.

  1979cited by this paper
• Effect of neurotensin on insulin, glucagon, and somatostatin release from isolated pancreatic islets.

  1979cited by this paper
• Half-life of somatostatin-like immunoreactivity in canine plasma.

  1979cited by this paper
• Physiological role of CCK, secretin and GIP in pancreatic and gastric somatostatin release

  1978cited by this paper
• Morphine and β-endorphin influence the secretion of the endocrine pancreas

  1978cited by this paper
• Vasoactive intestinal peptide stimulates pancreatic somatostatin release

  1978cited by this paper
• Modulation of pancreatic somatostatin by adrenergic and cholinergic agonism and by hyper- and hypoglycemic sulfonamides.

  1978cited by this paper
• Pancreatic and gastric somatostatin release in response to intragastric and intraduodenal nutrients and HCl in the dog.

  1978cited by this paper
• Somatostatin — both hormone and neurotransmitter?

  1978cited by this paper
• Properties of endogenous somatostatin-like immunoreactivity and synthetic somatostatin in dog plasma.

  1978cited by this paper
• Comparison of alpha-ketoisocaproic acid and glucose in rats: effects on insulin and somatostatin release and on islet cAMP content.

  1978cited by this paper
• Somatostatin-like immunoreactivity in rat blood. Characterization, regional differences, and responses to oral and intravenous glucose.

  1978cited by this paper
• Dissociation of effects of somatostatin antiserum on growth hormone and insulin secretion.

  1978cited by this paper
• Glucose and glucagon stimulate the secretion of somatostatin from the perfused canine pancreas.

  1978cited by this paper
• Morphine and beta-endorphin influence the secretion of the endocrine pancreas.

  1978cited by this paper
• Effects of glucose and arginine on the release of immunoreactive somatostatin from the isolated perfused rat pancreas

  1978cited by this paper
• The response of plasma somatostatin-like immunoreactivity to nutrients in normal and alloxan diabetic dogs.

  1978cited by this paper
• Dynamics of somatostatin and insulin release from isolated rat pancreatic islets: evidence for intraislet interactions between B cells and D cells.

  1978cited by this paper
• Somatostatin and Pancreatic Polypeptide Secretion: Effects of Glucagon, Insulin, and Arginine

  1978cited by this paper
• Secretion of somatostatin by rat islets of Langerhans and gastric mucosa and a role for pancreatic somatostatin in the regulation of glucagon release.

  1978cited by this paper
• Antisomatostatin serum increases levels of hormones from the pituitary and gut, but not from the pancreas.

  1978cited by this paper
• Studies of the physiology and pathophysiology of the pancreatic D cell.

  1978cited by this paper
• Gastrointestinal hormones and somatostatin release

  1978cited by this paper
• Physiologic Role of Somatostatin Insulin Release from Rat Islets Treated by Somatostatin Antiserum

  1977cited by this paper
• Pancreatic immunoreactive somatostatin release.

  1977cited by this paper
• Somatostatin and insulin release from isolated rat pancreatic islets in response to D-glucose, l-leucine, alpha-ketoisocaproic acid or D-glyceraldehyde: evidence for a regulatory role of adenosine-3' ,5'-cyclic monophosphate.

  1977cited by this paper
• Immunoreactive somatostatin levels in plasma of normal and alloxan diabetic dogs

  1977cited by this paper
• Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, pancreozymin-cholecystokinin, and tolbutamide.

  1977cited by this paper
• Dynamics of somatostatin release from isolated rat pancreatic islets

  1977cited by this paper
• Hypothesis: physiologic role of pancreatic somatostatin and the contribution of D-cell disorders to diabetes mellitus.

  1977cited by this paper
• The effects of gastrin, gastric inhibitory polypeptide, secretin, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas.

  1977cited by this paper
• Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes.

  1976cited by this paper
• INCREASED SOMATOSTATIN CONTENT OF ISLETS FROM STREPTOZOTOCIN‐DIABETIC RATS

  1976cited by this paper
• Response of pancreatic immunoreactive somatostatin to arginine.

  1976cited by this paper
• Somatostatin and insulin release from isolated rat pancreatic islets stimulated by glucose

  1976cited by this paper
• Stimulation of pancreatic immunoreactive somatostatin (IRS) release by glucagon [proceedings].

  1976cited by this paper
• Cyclic AMP-dependent stimulation of somatostatin secretion by isolated rat islets of Langerhans.

  1976cited by this paper
• Somatostatin: a review of its effects especially in human beings.

  1976cited by this paper
• A morphological basis for intercellular communication between alpha- and beta-cells in the endocrine pancreas.

  1975cited by this paper
• Functional subdivision of islets of Langerhans and possible role of D cells.

  1975cited by this paper
• Evidence for the D-Cell of the Pancreas Secreting Somatostatin

  1975cited by this paper
• Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

  1975cited by this paper
• Transport of rubidium and sodium in pancreatic islets

  1974cited by this paper
• The interrelationship between sodium and calcium fluxes across cell membranes.

  1974cited by this paper
• Sodium uptake by microdissected pancreatic islets: Effects of ouabain and chloromercuribenzene‐p‐sulphonic acid

  1974cited by this paper
• Structural coupling between pancreatic islet cells

  1973cited by this paper
• Interrelationship of islet metabolism, adenosine triphosphate content and insulin release.

  1973cited by this paper
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  1971cited by this paper
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  1971cited by this paper
• Kinetics of insulin release from the perfused rat pancreas caused by glucose, glucosamine, and galactose.

  1971cited by this paper
• Electrical activity in pancreatic islet cells: effect of ions

  1970cited by this paper
• Insulin responses to glucose: evidence for a two pool system in man.

  1969cited by this paper
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  1968cited by this paper
• Dynamics of insulin secretion by the perfused rat pancreas.

  1968cited by this paper
• EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS.

  1963cited by this paper

• Somatostatine

  2015cites this paper
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  2012cites this paper
• Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells.

  2010cites this paper
• Function and expression of somatostatin receptors of the endocrine pancreas.

  2008influential citation
• Pulses of somatostatin release are slightly delayed compared with insulin and antisynchronous to glucagon.

  2007cites this paper
• Loss of a priming effect of glucose on A and D cell secretion in perfused pancreases from alloxan-diabetic rats: Role of insulin and alloxan

  2004cites this paper
• Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function.

  2001cites this paper
• Homologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse.

  1999cites this paper
• Oscillatory Ca2+ signaling in somatostatin-producing cells from the human pancreas.

  1997cites this paper
• Glucokinase is located in secretory granules of pancreatic D‐cells

  1997cites this paper
• Antazoline increases insulin secretion and improves glucose tolerance in rats and dogs.

  1997cites this paper
• Glucose stimulation of somatostatin-producing islet cells involves oscillatory Ca2+ signaling.

  1996cites this paper
• Stimulation of somatostatin secretion by 3-O-methylglucose in the perfused dog pancreas

  1996cites this paper
• Neural regulation of the endocrine pancreas

  1995cites this paper
• Effects of insulin, glucagon, and somatostatin on the release of somatostatin-25 and somatostatin-14 from rainbow trout, Oncorhynchus mykiss, pancreatic islets in vitro.

  1995cites this paper
• Splanchnic Neural Regulation of Somatostatin Secretion in the Isolated Perfused Human Pancreas

  1994cites this paper
• Type II diabetes and syndrome X. Pathogenesis and glycemic management.

  1992cites this paper
• Sympathoadrenal system in neuroendocrine control of glucose: mechanisms involved in the liver, pancreas, and adrenal gland under hemorrhagic and hypoglycemic stress.

  1992cites this paper
• Immunocytochemical localization of muscarinic acetylcholine receptors in the rat endocrine pancreas

  1992cites this paper
• mediates arginine-induced somatostatin from isolated rat pancreatic islets

  1992cites this paper
• Glucagon mediates arginine-induced somatostatin secretion from isolated rat pancreatic islets.

  1992cites this paper
• Secretion and Radioimmunoassay of Somatostatin: In Vitro System

  1991cites this paper
• Porcine pancreastatin has no effect on endocrine secretion from the pig pancreas

  1990cites this paper
• Cholinergic regulation of the endocrine pancreas.

  1990cites this paper
• Abnormal Regulation by Glucose of Somatostatin Secretion in the Perfused Pancreas of NIDDM Rats

  1990cites this paper
• P2 purinoceptor agonists stimulate somatostatin secretion from dog pancreas.

  1990cites this paper
• Growth hormone and somatostatin in the plasma of transiently diabetic ducks: basal variation and response to glucose.

  1989cites this paper
• Regulatory peptides, the hypothalamus and diabetes

  1989cites this paper
• Radio-immunoassay of somatostatin from isolated rat pancreatic islets.

  1989cites this paper
• Hypersensitivity to arginine of both B and D pancreatic cells in adult streptozotocin-diabetic rats.

  1989cites this paper
• Somatostatin secretion from isolated rat pancreatic islets.

  1989cites this paper
• Paradoxical effects of endogenous and exogenous insulin on amino acid transport activity in the isolated rat pancreas: somatostatin-14 inhibits insulin action

  1989cites this paper
• Involvement of a central nervous pathway in yohimbine-induced insulin secretion.

  1989cites this paper
• Effects of galanin on the release of insulin, glucagon and somatostatin from the isolated, perfused dog pancreas.

  1988cites this paper
• Effect of insulin on basal pancreaticoduodenal output of somatostatin in normal and diabetic dogs.

  1988cites this paper
• Glucose, beta adrenergic effects, and pancreatic endocrine function in the isolated perfused duck pancreas.

  1987cites this paper
• HEPATIC DRUG METABOLISM IS INCREASED IN POORLY CONTROLLED INSULIN DEPENDENT DIABETES MELLITUS (IDDM)

  1987cites this paper
• Time Dependent Stimulating Effect of Glucagon on the Capacity of Urea-N Synthesis in Rats

  1987cites this paper
• Evidence that hyperglycemia increases muscarinic binding in pancreatic islets of the rat.

  1987cites this paper
• Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion

  1986cites this paper
• Glucagon and somatostatin secretion from the perfused splenic bulb of duck pancreas.

  1986cites this paper
• Effect and mechanism of vagal nerve stimulation on somatostatin secretion in dogs.

  1986cites this paper
• Gigantism Associated with McCune-Albright's Syndrome

  1985cites this paper
• Reversal of D- and A-Cell Insensitivity to Glucose in Alloxan-diabetic Dogs by Treatment with the Artificial Beta Cell (Biostator)

  1985cites this paper
• Somatostatin secretion from the isolated perfused dog ileum.

  1985cites this paper
• Effects of a thiazide diuretic (hydroflumethiazide) and a loop diuretic (bumetanide) on the endocrine pancreas: studies in vitro.

  1985cites this paper
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  1985cites this paper
• Abnormal D cell secretion in alloxan-diabetes: influence by drug and aberrant metabolism.

  1984cites this paper
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  1984cites this paper
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  1984cites this paper
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  1984cites this paper
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  1984cites this paper
• In vivo stimulation of pancreatic hormone secretion by norepinephrine infusion in the dog.

  1984cites this paper
• Glucose inhibits insulin release when not promoting the entry of calcium into the beta-cells.

  1984cites this paper
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  1983cites this paper
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  1983cites this paper
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  1983cites this paper
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  1983cites this paper
• Glucose- and arginine-induced insulin and glucagon responses from the isolated perfused pancreas of the BB-Wistar diabetic rat. Evidence for selective impairment of glucose regulation.

  1983cites this paper
• Stimulatory Effect of Beta-Hydroxybutyrate on the Release of Somatostatin from the Isolated Pancreas of Normal and Streptozotocin-Diabetic Dogs

  1982cites this paper
• Difference in calcium dependency of insulin, glucagon and somatostatin secretion in response to glibenclamide in perfused rat pancreas

  1982influential citation
• Glucose and glucagon do stimulate somatostatin release from isolated pancreatic islets

  1981cites this paper
• Characterisation of the abnormal pancreatic D and A cell function in streptozotocin diabetic dogs: Studies with D-glyceraldehyde, dihydroxyacetone, D-mannoheptulose, D-glucose, and L-arginine

  1981cites this paper