Phosphorylation of STIM1 at ERK1/2 target sites regulates interaction with the microtubule plus-end binding protein EB1

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Cell Science

• Publication date

  2013-07-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1242/jcs.125054PMID 23687376
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2012influential reference
• Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo–activated ERK1/2 is critical for the promyogenic function of Stim1

  2012influential reference
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  2011influential reference
• Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

  2010influential reference
• Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis

  2010influential reference
• Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry

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  2010cited by this paper
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• STIM1-dependent and STIM1-independent Function of Transient Receptor Potential Canonical (TRPC) Channels Tunes Their Store-operated Mode*

  2010cited by this paper
• Phosphorylation of CLASP2 by GSK-3β regulates its interaction with IQGAP1, EB1 and microtubules

  2009influential reference
• SOAR and the polybasic STIM1 domains gate and regulate the Orai channels

  2009cited by this paper
• Visualizing the store-operated channel complex assembly in real time: identification of SERCA2 as a new member.

  2009cited by this paper
• Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis

  2009cited by this paper
• GSK3β phosphorylation modulates CLASP–microtubule association and lamella microtubule attachment

  2009influential reference
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  2009cited by this paper
• Orai1 internalization and STIM1 clustering inhibition modulate SOCE inactivation during meiosis

  2009cited by this paper
• An EB1-binding motif acts as a microtubule tip localization signal.

  2009cited by this paper
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  2008influential reference
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• Ca2+-store-dependent and -independent reversal of Stim1 localization and function

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• Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion

  2007influential reference
• Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1

  2007cited by this paper
• STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

  2007cited by this paper
• The selectivity of protein kinase inhibitors: a further update.

  2007cited by this paper
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  2006influential reference
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  2006influential reference
• Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum

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  2006influential reference
• Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity.

  2006influential reference
• STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

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• Store-operated calcium entry in differentiated C2C12 skeletal muscle cells.

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  2005cited by this paper
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  2004influential reference
• Aurora B regulates MCAK at the mitotic centromere.

  2004influential reference
• Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation.

  2001influential reference
• An examination of the secretion‐like coupling model for the activation of the Ca2+ release‐activated Ca2+ current ICRAC in RBL‐1 cells

  2001cited by this paper
• STIM1: a novel phosphoprotein located at the cell surface.

  2000cited by this paper
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  1997cited by this paper
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  year unknowncited by this paper

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  2026cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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