Frequent promoter hypermethylation of RASSF1A and p16INK4a and infrequent allelic loss other than 9p21 in betel-associated oral carcinoma in a Vietnamese non-smoking/non-drinking female population.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Oral Pathology & Medicine

• Publication date

  2005-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/J.1600-0714.2004.00292.XPMID 15689228
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.

  2003cited by this paper
• p53 mutations in betel-associated oral cancer from Thailand.

  2003cited by this paper
• Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers

  2003cited by this paper
• Promoter hypermethylation profile of tumor‐associated genes p16, p15, hMLH1, MGMT and E‐cadherin in oral squamous cell carcinoma

  2003cited by this paper
• Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma

  2003cited by this paper
• K-ras mutations and RASSF1A promoter methylation in colorectal cancer

  2002cited by this paper
• Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters.

  2002cited by this paper
• Assessing the use of p16(INK4a) promoter gene methylation in serum for detection of bladder cancer.

  2002cited by this paper
• Poorly differentiated adenocarcinoma and mucinous carcinoma of the colon and rectum show higher rates of loss of heterozygosity and loss of E‐cadherin expression due to methylation of promoter region

  2002cited by this paper
• The correlation between CpG methylation and protein expression of P16 in oral squamous cell carcinomas.

  2002cited by this paper
• Alterations of p16(INK4a) and p14(ARF) in patients with severe oral epithelial dysplasia.

  2002cited by this paper
• The incidence of oropharyngeal cancer in Taiwan: an endemic betel quid chewing area.

  2002cited by this paper
• Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma.

  2002cited by this paper
• Inactivation of the p14ARF, p15INK4B and p16INK4A genes is a frequent event in human oral squamous cell carcinomas

  2001cited by this paper
• A High Frequency of Allelic Loss in Oral Verrucous Lesions May Explain Malignant Risk

  2001cited by this paper
• High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma.

  2001cited by this paper
• Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas.

  2001cited by this paper
• Accumulative increase of loss of heterozygosity from leukoplakia to foci of early cancerization in leukoplakia of the oral cavity

  2001cited by this paper
• p16(MTS-1/CDKN2/INK4a) in cancer progression.

  2001cited by this paper
• Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma.

  2001cited by this paper
• Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers.

  2001cited by this paper
• Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3

  2000cited by this paper
• Characteristics of mutations in the p53 gene of oral squamous‐cell carcinomas associated with betel‐quid chewing in Sri Lanka. Int. J. Cancer 77, 839–842 (1998)

  1999cited by this paper
• Low incidence of p53 mutations in betel quid and tobacco chewing-associated oral squamous carcinoma from India.

  1999cited by this paper
• Fractional allele loss indicates distinct genetic populations in the development of squamous cell carcinoma of the head and neck (SCCHN).

  1999cited by this paper
• Location of candidate tumour suppressor gene loci at chromosomes 3p, 8p and 9p for oral squamous cell carcinomas

  1999cited by this paper
• Prognostic significance of p53 protein overexpression in betel‐ and tobacco‐related oral oncogenesis

  1998cited by this paper
• Characteristics of mutations in the p53 gene of oral squamous‐cell carcinomas associated with betel‐quid chewing in Sri Lanka

  1998cited by this paper
• Genetic alterations of chromosome band 9p21 – 22 in head and neck cancer are not restricted to p16INK4a

  1997cited by this paper
• Loss of heterozygosity of APC and MCC genes in oral squamous cell carcinomas in Taiwan.

  1997cited by this paper
• Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

  1996cited by this paper
• Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

  1996cited by this paper
• p53, Rb, and cyclin D1 expression in human oral verrucous carcinomas

  1996cited by this paper
• Betel chewer's mucosa in elderly Cambodian women.

  1996cited by this paper
• Oral cancer and precancer related to betel and miang chewing in Thailand: a review.

  1995cited by this paper
• High prevalence of expression of p53 oncoprotein in oral carcinomas from India associated with betel and tobacco chewing.

  1995cited by this paper
• An allelotype of squamous carcinoma of the head and neck using microsatellite markers.

  1994cited by this paper
• Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea.

  1994cited by this paper
• Allelotype of head and neck squamous cell carcinoma.

  1994cited by this paper
• Overexpression of p53 protein in betel‐ and tobacco‐related human oral dysplasia and squamous‐cell carcinoma in India

  1994cited by this paper
• Low prevalence of expression of p53 oncoprotein in oral carcinomas from Sri Lanka associated with betel and tobacco chewing.

  1993cited by this paper
• Some oral carcinomas from Sri Lankan betel/tobacco chewers overexpress p53 oncoprotein but lack mutations in exons 5-9.

  1993cited by this paper
• Three discrete regions of deletion at 3p in head and neck cancers.

  1993cited by this paper

• Loss of Heterozygosity in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma – A Scoping Review

  2025cites this paper
• Epigenetic Regulation in Oral Squamous Cell Carcinoma Microenvironment: A Comprehensive Review

  2023cites this paper
• Portrait of DNA methylated genes predictive of poor prognosis in head and neck cancer and the implication for targeted therapy

  2021cites this paper
• ASSESSMENT OF SERUM TOTAL SIALIC ACID AND LIPID BOUND SIALIC ACID LEVELS IN PATIENTS WITH LEUKOPLAKIAAND ORAL SQUAMOUS CELL CARCINOMA-A CASE CONTROL STUDY

  2020cites this paper
• Oral Cancer

  2019cites this paper
• Promoter Hypermethylation of Tumor-Suppressor Genes p16INK4a, RASSF1A, TIMP3, and PCQAP/MED15 in Salivary DNA as a Quadruple Biomarker Panel for Early Detection of Oral and Oropharyngeal Cancers

  2019cites this paper
• State of methylation and epigenome studies in some types of head and neck cancer

  2018cites this paper
• Associations of RASSF1A, RARβ, and CDH1 promoter hypermethylation with oral cancer risk

  2018cites this paper
• Study of the promoter methylation status of RASSF1A gene in oral squamous cell carcinoma

  2018influential citation
• Role of mucosal high-risk human papillomavirus types in head and neck cancers in Romania

  2018cites this paper
• Buschke-Löwenstein-Tumor

  2017cites this paper
• Interaction Between Rare Variants in NOTCH1 and Betel Quid Chewing in Oral Squamous Cell Carcinoma

  2017cites this paper
• Longer Duration and Earlier Age of Onset of Paternal Betel Chewing and Smoking Increase Metabolic Syndrome Risk in Human Offspring, Independently, in a Community-Based Screening Program in Taiwan

  2016cites this paper
• Diagnostic Biomarkers in Oral Verrucous Carcinoma: A Systematic Review

  2016cites this paper
• Clinical Relevance of Serum Total Sialic Acid In Oral Leukoplakia and Oral Squamous Cell Carcinoma - A Randomized Study.

  2015cites this paper
• Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival

  2015cites this paper
• Molecular and cellular cues of diet-associated oral carcinogenesis--with an emphasis on areca-nut-induced oral cancer development.

  2015cites this paper
• Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b.

  2014cites this paper
• Downregulated miR 329 and miR 410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7 b

  2014cites this paper
• Epigenetic regulation of the X‐linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma

  2013cites this paper
• Association of Betel Nut with Carcinogenesis: Revisit with a Clinical Perspective

  2012cites this paper
• 16 Epigenetic Profiling of Oral Cancer

  2012cites this paper
• Epigenome and DNA methylation in oral squamous cell carcinoma.

  2012cites this paper
• Epigenetic mechanisms in oral carcinogenesis.

  2012cites this paper
• Epigenetic Profiling of Oral Cancer

  2012cites this paper
• Methylation-Mediated Molecular Dysregulation in Clinical Oral Malignancy

  2012cites this paper
• Promoter hypermethylation in primary squamous cell carcinoma of the oral cavity and oropharynx: a study of a Brazilian cohort

  2012cites this paper
• The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma

  2011cites this paper
• DNA hypermethylation as an epigenetic mark for oral cancer diagnosis.

  2011cites this paper
• DNA methylation in oral squamous cell carcinoma: molecular mechanisms and clinical implications.

  2011cites this paper
• Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma.

  2009cites this paper
• No mutations found in exon 2 of gene p16CDKN2A during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide

  2009cites this paper
• Methylation of RASSF1A, RASSF2A, and HIN-1 Is Associated with Poor Outcome after Radiotherapy, but not Surgery, in Oral Squamous Cell Carcinoma

  2009cites this paper
• Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation

  2009cites this paper
• Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma.

  2009cites this paper
• Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma

  2008cites this paper
• High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka.

  2008cites this paper
• [Exploration of tumor suppressors p16INK4a and p14ARF in oral leukoplakias].

  2007cites this paper
• Untersuchung der Tumorsuppressoren p16INK4a und p14ARF in Mundschleimhautleukoplakien

  2007cites this paper
• Use of tissue autofluorescence in the detection of oral premalignant lesions with high risk molecular patterns

  2006cites this paper
• Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.

  2006cites this paper
• Tumeur de Buschke-Löwenstein

  2005cites this paper
• Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.

  1992cites this paper