Induction of tubulin polymerization and apoptosis in malignant mesothelioma cells by a new compound JBIR-23.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Cancer Letters

• Publication date

  2011-01-28

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.canlet.2010.10.005PMID 21055871
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004influential reference
• Neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma.

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  1995cited by this paper
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  1993cited by this paper

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