A transgenic zebrafish model for monitoring xbp1 splicing and endoplasmic reticulum stress in vivo.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Mechanisms of Development

• Publication date

  2015-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.mod.2015.04.001PMID 25892297
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cross talk between ER stress, oxidative stress, and inflammation in health and disease.

  2015cited by this paper
• Endoplasmic Reticulum Stress, Genome Damage, and Cancer

  2015cited by this paper
• The impact of the endoplasmic reticulum protein-folding environment on cancer development

  2014cited by this paper
• Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish

  2014cited by this paper
• Druggable sensors of the unfolded protein response.

  2014cited by this paper
• Organelle and proteome quality control mechanisms: how cells are able to keep calm and carry on

  2014cited by this paper
• Endoplasmic Reticulum Stress and Cancer

  2014cited by this paper
• The E3 ubiquitin ligase gp78 protects against ER stress in zebrafish liver.

  2014cited by this paper
• Endoplasmic reticulum dysfunction in neurological disease.

  2013cited by this paper
• Endoplasmic reticulum stress sensing in the unfolded protein response.

  2013cited by this paper
• The role of the unfolded protein response in diabetes mellitus

  2013cited by this paper
• Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish

  2013cited by this paper
• Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease

  2013cited by this paper
• Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology

  2012cited by this paper
• Endoplasmic reticulum stress and type 2 diabetes.

  2012cited by this paper
• Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion, mitochondrial membrane potential (DeltaPsi m), and embryo development.

  2012cited by this paper
• Inhibition of Endoplasmic Reticulum Stress Improves Mouse Embryo Development

  2012cited by this paper
• The impact of the unfolded protein response on human disease

  2012cited by this paper
• Stress management: How the unfolded protein response impacts fatty liver disease.

  2012cited by this paper
• A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development

  2012cited by this paper
• Effect of Endoplasmic Reticulum Stress on Porcine Oocyte Maturation and Parthenogenetic Embryonic Development In Vitro1

  2012cited by this paper
• Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt‐deficient zebrafish

  2011cited by this paper
• The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

  2011cited by this paper
• Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure.

  2011cited by this paper
• Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell.

  2010cited by this paper
• Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth.

  2010cited by this paper
• Endoplasmic reticulum stress and the unfolded protein response.

  2009cited by this paper
• Targeting ASK1 in ER stress-related neurodegenerative diseases

  2009cited by this paper
• Targeting the endoplasmic reticulum-stress response as an anticancer strategy.

  2009cited by this paper
• Unfolded protein response in a Drosophila model for retinal degeneration

  2007cited by this paper
• Nodal signaling activates differentiation genes during zebrafish gastrulation.

  2007cited by this paper
• Signal integration in the endoplasmic reticulum unfolded protein response

  2007cited by this paper
• The xbp-1 gene is essential for development in Drosophila

  2007cited by this paper
• Functional Dissection of the Tol2 Transposable Element Identified the Minimal cis-Sequence and a Highly Repetitive Sequence in the Subterminal Region Essential for Transposition

  2006cited by this paper
• Zebrafish assays for drug toxicity screening

  2006cited by this paper
• Endoplasmic reticulum stress signaling in disease.

  2006cited by this paper
• Two Different Transgenes to Study Gene Silencing and Re-Expression During Zebrafish Caudal Fin and Retinal Regeneration

  2006cited by this paper
• XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos.

  2006cited by this paper
• The dynamic ER: experimental approaches and current questions.

  2005cited by this paper
• In vivo zebrafish assays for toxicity testing.

  2005cited by this paper
• Zebrafish as a model vertebrate for investigating chemical toxicity.

  2005cited by this paper
• In vivo drug discovery in the zebrafish

  2005cited by this paper
• Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening.

  2004cited by this paper
• The unfolded protein response regulates glutamate receptor export from the endoplasmic reticulum.

  2004cited by this paper
• A transgenic mouse model for monitoring endoplasmic reticulum stress

  2004cited by this paper
• A trip to the ER: coping with stress.

  2004cited by this paper
• Xenopus X-box binding protein 1, a leucine zipper transcription factor, is involved in the BMP signaling pathway.

  2003cited by this paper
• Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

  2002cited by this paper
• Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development.

  2001cited by this paper
• XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.

  2001cited by this paper
• An essential role in liver development for transcription factor XBP-1.

  2000cited by this paper
• Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation.

  2000cited by this paper
• A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the Unfolded Protein Response

  1996cited by this paper
• A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response.

  1996cited by this paper
• The zebrafish midblastula transition.

  1993cited by this paper

• ER Stress Ire1‐Xbp1s Pathway Maintains Youthful Epidermal Basal Layer Through the Regulation of Cell Proliferation

  2025cites this paper
• Oxidative stress-induced intervertebral disc remodelling and elevated stiffness drive idiopathic scoliosis in preclinical models

  2025cites this paper
• Pancreatic exocrine damage induces beta cell stress in zebrafish larvae

  2025cites this paper
• A JAGN1-associated severe congenital neutropenia zebrafish model revealed an altered G-CSFR signaling and UPR activation

  2024cites this paper
• The tunicamycin derivative TunR2 exhibits potent antibiotic properties with low toxicity in an in vivo Mycobacterium marinum-zebrafish TB infection model

  2024cites this paper
• Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish.

  2024cites this paper
• A statistical mechanics investigation of unfolded protein response across organisms

  2024cites this paper
• Gene module reconstruction elucidates cellular differentiation processes and the regulatory logic of specialized secretion

  2023cites this paper
• Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae

  2022cites this paper
• Translational control by maternal Nanog promotes oogenesis and early embryonic development.

  2022cites this paper
• Translation control by maternal Nanog promotes oocyte maturation and early embryonic development

  2022cites this paper
• Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

  2022cites this paper
• A comprehensive review on genetically modified fish: key techniques, applications and future prospects

  2021cites this paper
• Transcriptomic Diversity in the Livers of South African Sardines Participating in the Annual Sardine Run

  2021cites this paper
• Use of Zebrafish Models to Boost Research in Rare Genetic Diseases

  2021cites this paper
• Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos.

  2020cites this paper
• SRP54 mutations induce Congenital Neutropenia via dominant-negative effects on XBP1 splicing.

  2020cites this paper
• β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors

  2020cites this paper
• Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders

  2020cites this paper
• Spastin mutations impair coordination between lipid droplet dispersion and reticulum

  2020influential citation
• High fat diet induces microbiota-dependent silencing of enteroendocrine cells

  2019cites this paper
• Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease

  2019influential citation
• Epithelial delamination is protective during pharmaceutical-induced enteropathy

  2019cites this paper
• NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy

  2019cites this paper
• Endoplasmic reticulum stress signalling – from basic mechanisms to clinical applications

  2018cites this paper
• Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer’s disease

  2017cites this paper
• Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo

  2017cites this paper
• Application of Zebrafish Model to Environmental Toxicology.

  2016cites this paper