CD95 signaling deficient mice with a wild-type hematopoietic system are prone to hepatic neoplasia

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Apoptosis

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10495-007-0149-6PMID 17955374
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

  2007cited by this paper
• Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma.

  2007cited by this paper
• The CD95 receptor: apoptosis revisited.

  2007cited by this paper
• Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.

  2006cited by this paper
• p205, A potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation

  2006cited by this paper
• Inherited and acquired death receptor defects in human Autoimmune Lymphoproliferative Syndrome.

  2006cited by this paper
• Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma.

  2006cited by this paper
• IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.

  2005cited by this paper
• CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells1

  2005cited by this paper
• Does CD95 have tumor promoting activities?

  2005cited by this paper
• Induction of apoptosis and activation of NF‐κB by CD95 require different signalling thresholds

  2004cited by this paper
• NF-κB functions as a tumour promoter in inflammation-associated cancer

  2004cited by this paper
• T Cell–specific Ablation of Fas Leads to Fas Ligand–mediated Lymphocyte Depletion and Inflammatory Pulmonary Fibrosis

  2004cited by this paper
• NF-kappaB functions as a tumour promoter in inflammation-associated cancer.

  2004cited by this paper
• Inhibition of spontaneous development of liver tumors by inoculation with dendritic cells loaded with hepatocellular carcinoma cells in C3H/HeNCRJ mice

  2004influential reference
• CD95 ligand induces motility and invasiveness of apoptosis‐resistant tumor cells

  2004cited by this paper
• Fas engagement induces neurite growth through ERK activation and p35 upregulation

  2003cited by this paper
• The CD95(APO-1/Fas) DISC and beyond

  2003cited by this paper
• Effective Destruction of Fas-deficient Insulin-producing β Cells in Type 1 Diabetes

  2003cited by this paper
• NF-kappaB in cancer: a marked target.

  2003cited by this paper
• Non-apoptotic Fas signaling.

  2003cited by this paper
• NF-κB in cancer: a marked target

  2003cited by this paper
• Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice.

  2002cited by this paper
• Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A

  2002influential reference
• The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis.

  2001cited by this paper
• Anti-Fas Induces Hepatic Chemokines and Promotes Inflammation by an NF-κB-independent, Caspase-3-dependent Pathway*

  2001cited by this paper
• Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection.

  2001cited by this paper
• Immunological characterization of C3H mice congenic for Faslprcg , C3H/HeJ-Faslprcg /Faslprcg

  2000cited by this paper
• Fas engagement accelerates liver regeneration after partial hepatectomy

  2000cited by this paper
• Defining CD95 as a tumor suppressor gene

  2000cited by this paper
• Cathepsin S required for normal MHC class II peptide loading and germinal center development.

  1999cited by this paper
• Fas ligand-induced apoptosis.

  1999cited by this paper
• Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice.

  1999cited by this paper
• Expression and Function of Fas on Cells Damaged by γ-Irradiation in B6 and B6/lpr Mice

  1998cited by this paper
• Expression and function of Fas on cells damaged by gamma-irradiation in B6 and B6/lpr mice.

  1998cited by this paper
• Hepatocyte proliferative activity in chronic liver damage as assessed by the monoclonal antibody MIB1 Ki67 in archival material: The role of etiology, disease activity, iron, and lipid peroxidation

  1996influential reference
• Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

  1995cited by this paper
• The APO‐1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice

  1994cited by this paper
• The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.

  1994cited by this paper
• gld/gld mice are unable to express a functional ligand for Fas

  1994cited by this paper
• Autoimmunity in mice bearing lprcg: a novel mutant gene.

  1994cited by this paper
• Lethal effect of the anti-Fas antibody in mice

  1993cited by this paper
• Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

  1992influential reference
• Inhibition of spontaneous hepatocarcinogenesis in C3H/HeN mice by transplanted hepatocellular carcinomas.

  1981cited by this paper
• Studies on the occurrence of spontaneous hepatomas in mice of strains C3H and CBA.

  1950cited by this paper

• Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus‐Prone Mice

  2016influential citation
• Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?

  2015cites this paper
• The role of CD95 and CD95 ligand in cancer

  2015cites this paper
• CD95 signaling in cancer treatment.

  2014cites this paper
• CD95 death receptor and epidermal growth factor receptor (EGFR) in liver cell apoptosis and regeneration.

  2012cites this paper
• Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury.

  2011cites this paper
• CD95 promotes tumour growth

  2011cites this paper
• Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase.

  2011cites this paper
• CD95/Fas promotes tumour growth

  2010cites this paper
• Cancer: A wolf in wolf's clothing

  2010cites this paper
• CD95 is cytoprotective for intestinal epithelial cells in colitis

  2010cites this paper
• Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.

  2009cites this paper
• Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands.

  2009cites this paper
• Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing.

  2008cites this paper
• The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

  2008cites this paper