Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Free Radical Biology & Medicine

• Publication date

  2012-01-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.freeradbiomed.2011.10.448PMID 22064365
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Oxygen effect in the radiolysis of proteins. IV. Myoglobin.

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• Quantification of protein modification by oxidants.

  2009influential reference
• Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins.

  2008influential reference
• Cleavage of peptides and proteins using light-generated radicals from titanium dioxide.

  2007influential reference
• Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals.

  2006cited by this paper
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• Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones.

  2002influential reference
• Protein Damage and Degradation by Oxygen Radicals

  2001cited by this paper
• Protein oxidation and ageing.

  2001cited by this paper
• Generation and propagation of radical reactions on proteins.

  2001cited by this paper
• Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque.

  1998cited by this paper
• EPR studies on the selectivity of hydroxyl radical attack on amino acids and peptides

  1998cited by this paper
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  1998cited by this paper
• Structural characterization of the products of hydroxyl-radical damage to leucine and their detection on proteins.

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• Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?

  1997cited by this paper
• Protein hydroperoxides as new reactive oxygen species.

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  1997cited by this paper
• Comparison of 5-hydroxy-2-amino valeric acid with carbonyl group content as a marker of oxidized protein in human and mouse liver tissues.

  1996cited by this paper
• The utilization of 5-hydroxyl-2-amino valeric acid as a specific marker of oxidized arginine and proline residues in proteins.

  1996cited by this paper
• Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage.

  1996cited by this paper
• Structural identification of valine hydroperoxides and hydroxides on radical-damaged amino acid, peptide, and protein molecules.

  1995cited by this paper
• Biological fate of amino acid, peptide and protein hydroperoxides.

  1995cited by this paper
• Protein hydroperoxides can give rise to reactive free radicals.

  1995cited by this paper
• [18] Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides

  1994cited by this paper
• Oxygen effect in the radiolysis of proteins

  1994cited by this paper
• Formation of peroxides in amino acids and proteins exposed to oxygen free radicals.

  1993cited by this paper
• Radical-induced chain oxidation of proteins and its inhibition by chain-breaking antioxidants.

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• Long-lived reactive species on free-radical-damaged proteins.

  1992cited by this paper
• Oxidative fragmentation of collagen and prolyl peptide by Cu(II)/H2O2. Conversion of proline residue to 2-pyrrolidone.

  1992influential reference
• Susceptibility of glutathione peroxidase to proteolysis after oxidative alteration by peroxides and hydroxyl radicals.

  1991cited by this paper
• A novel mechanism for oxidative cleavage of prolyl peptides induced by the hydroxyl radical.

  1990influential reference
• Determination of carbonyl content in oxidatively modified proteins.

  1990cited by this paper
• Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions.

  1989cited by this paper
• Histidine and proline are important sites of free radical damage to proteins.

  1989cited by this paper
• Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (⋅OH/⋅O− in Aqueous Solution

  1988influential reference
• Protein damage and degradation by oxygen radicals. II. Modification of amino acids.

  1987cited by this paper
• Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.

  1987cited by this paper
• Protein damage and degradation by oxygen radicals. I. general aspects.

  1987cited by this paper
• The chemical basis of radiation biology

  1987cited by this paper
• Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure.

  1987cited by this paper
• Fragmentation of proteins by free radicals and its effect on their susceptibility to enzymic hydrolysis.

  1986cited by this paper
• Free radicals in biology and medicine

  1985cited by this paper
• Reactivity of HO2/O−2 Radicals in Aqueous Solution

  1985cited by this paper
• Oxygen effect in the radiolysis of proteins. Part 2. Bovine serum albumin.

  1984cited by this paper
• REACTION MECHANISMS IN THE RADIOLYSIS OF PEPTIDES, POLYPEPTIDES AND PROTEINS II REACTIONS AT SIDE-CHAIN LOCI IN MODEL SYSTEMS

  1982cited by this paper
• Oxygen effect in the radiolysis of proteins. I. Lactate dehydrogenase.

  1980cited by this paper
• Fluorescence properties of o-phthaldialdehyde derivatives of amino acids.

  1979cited by this paper
• Enthalpy of decomposition of hydrogen peroxide by catalase at 25 degrees C (with molar extinction coefficients of H 2 O 2 solutions in the UV).

  1972cited by this paper
• Enthalpy of Decomposition of Hydrogen Peroxide by Catalase at 25C (with Molar Extinction Coefficients of H2O2 Solutions in the UV)

  1972cited by this paper
• Studies by electron spin resonance of the reactions of alkylperoxy radicals. Part 2.—Equilibrium between alkylperoxy radicals and tetroxide molecules

  1970cited by this paper
• Additions and Corrections: Deuterium-isotope Effects in the Autoxidation of Aralkyl Hydrocarbons. Mechanism of the Interaction of Peroxy Radicals.

  1958cited by this paper
• Deuterium-isotope Effects in the Autoxidation of Aralkyl Hydrocarbons. Mechanism of the Interaction of PEroxy Radicals1

  1957cited by this paper

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