Perturbation of the Intermolecular Contact Regions (Molecular Surface) of Hemoglobin S by Intramolecular, Low-O2-Affinity-Inducing Central Cavity Cross-Bridges

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Protein Chemistry

• Publication date

  2000-05-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1023/A:1007039111556PMID 11043930
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An improved process for the production of sterile modified haemoglobin solutions.

  1997cited by this paper
• Probing the Hemoglobin Central Cavity by Direct Quantification of Effector Binding Using Fluorescence Lifetime Methods*

  1997cited by this paper
• Structural characterization of human hemoglobin crosslinked by bis(3,5‐dibromosalicyl) fumarate using mass spectrometric techniques

  1997cited by this paper
• The structural link between polymerization and sickle cell disease.

  1997cited by this paper
• Production and characteristics of an infusible oxygen-carrying fluid based on hemoglobin intramolecularly cross-linked with sebacic acid.

  1996cited by this paper
• Intramolecular cross-linking of oxy hemoglobin by bis sulfosuccinimidyl suberate and sebacate: generation of cross-linked hemoglobin with reduced oxygen affinity.

  1995cited by this paper
• Preparation of intramolecularly cross-linked hemoglobins.

  1994cited by this paper
• The chloride effect in human haemoglobin. A new kind of allosteric mechanism.

  1994cited by this paper
• Influence of the chemical nature of side chain at beta 108 of hemoglobin A on the modulation of the oxygen affinity by chloride ions. Low oxygen affinity variants of human hemoglobin expressed in transgenic pigs: hemoglobins Presbyterian and Yoshizuka.

  1994cited by this paper
• Effect of intramolecular cross-links on the enthalpy and quaternary structure of the intermediates of oxygenation of human hemoglobin.

  1993cited by this paper
• Intermolecular contacts within sickle hemoglobin fibers

  1991cited by this paper
• Sickle cell hemoglobin polymerization.

  1990cited by this paper
• New effectors of human hemoglobin: structure and function.

  1990cited by this paper
• Intermolecular contacts within sickle hemoglobin fibers.

  1989cited by this paper
• Isolation and characterization of a new hemoglobin derivative cross-linked between the alpha chains (lysine 99 alpha 1----lysine 99 alpha 2).

  1986cited by this paper
• Refined crystal structure of deoxyhemoglobin S. II. Molecular interactions in the crystal.

  1985cited by this paper
• Schiff base adducts of glyceraldehyde with hemoglobin. Differences in the Amadori rearrangement at the alpha-amino groups.

  1983cited by this paper
• Mechanism for the increase in solubility of deoxyhemoglobin S due to cross-linking the beta chains between lysine-82 beta 1 and lysine-82 beta 2.

  1982cited by this paper
• Beta-chain contact sites in the haemoglobin S polymer.

  1980cited by this paper
• Development of antisickling compounds that chemically modify hemoglobin S specifically within the 2,3-diphosphoglycerate binding site.

  1980cited by this paper
• Diaspirins that cross-link beta chains of hemoglobin: bis(3,5-dibromosalicyl) succinate and bis(3,5-dibromosalicyl) fumarate.

  1979cited by this paper
• Oxygen affinity as an index of hemoglobin S polymerization: a new micromethod.

  1978cited by this paper
• Crystal structure of sickle-cell deoxyhemoglobin at 5 A resolution.

  1975cited by this paper
• Structure of inositol hexaphosphate–human deoxyhaemoglobin complex

  1974cited by this paper
• X-ray Diffraction Study of Binding of 2,3-Diphosphoglycerate to Human Deoxyhaemoglobin

  1972cited by this paper
• Nuclear magnetic resonance quadrupole relaxation studies of chloride binding to human oxy- and deoxyhaemoglobin.

  1972cited by this paper
• Gene Mutations in Human Hæmoglobin: the Chemical Difference Between Normal and Sickle Cell Hæmoglobin

  1957cited by this paper
• A Specific Chemical Difference Between the Globins of Normal Human and Sickle-Cell Anæmia Hæmoglobin

  1956cited by this paper
• Studies on the Destruction of Red Blood Cells. VIII. Molecular Orientation in Sickle Cell Hemoglobin Solutions.∗

  1950cited by this paper

• Examining and Mitigating Acellular Hemoglobin Vasoactivity

  2013cites this paper
• NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA.

  2010cites this paper
• Preparation and Characterization of Dimeric Bovine Hemoglobin Tetramers

  2003cites this paper