Rapid task-dependent tuning of the mouse olfactory bulb

Anzhelika Koldaeva,Andreas T. Schaefer,I. Fukunaga

Published 2018 in bioRxiv

ABSTRACT

Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area, the mouse olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.

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