Synaptic Plasma Membrane Na+, K+-ATPase Activity is Significantly Reduced by the α-Keto Acids Accumulating in Maple Syrup Urine Disease in Rat Cerebral Cortex

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Metabolic brain disease

• Publication date

  2007-02-13

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s11011-007-9046-5PMID 17295076
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats

  2005cited by this paper
• α-Keto Acids Accumulating in Maple Syrup Urine Disease Stimulate Lipid Peroxidation and Reduce Antioxidant Defences in Cerebral Cortex From Young Rats

  2005cited by this paper
• Inhibition of Na+, K+‐ATPase activity in rat striatum by the metabolites accumulated in Lesch–Nyhan disease

  2004cited by this paper
• Intrahippocampal administration of the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats.

  2004cited by this paper
• Dysmyelination in the brain of adolescents and young adults with maple syrup urine disease.

  2004cited by this paper
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  2003cited by this paper
• Effect of Leucine Administration on Creatine Kinase Activity in Rat Brain

  2003cited by this paper
• Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress

  2003cited by this paper
• Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease.

  2003cited by this paper
• Creatine Kinase Activity from Rat Brain Is Inhibited by Branched-Chain Amino Acids in Vitro

  2003cited by this paper
• Na(+), K(+)-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death.

  2003cited by this paper
• Inhibition of brain energy metabolism by the α-keto acids accumulating in maple syrup urine disease

  2003cited by this paper
• Induction of oxidative stress in rat brain by the metabolites accumulating in maple syrup urine disease

  2003cited by this paper
• Ionic Mechanism of Ouabain-Induced Concurrent Apoptosis and Necrosis in Individual Cultured Cortical Neurons

  2002cited by this paper
• Stimulation of Lipid Peroxidation in Vitro in Rat Brain by the Metabolites Accumulating in Maple Syrup Urine Disease

  2002cited by this paper
• Inhibition of Na+, K+-ATPase Activity by the Metabolites Accumulating in Homocystinuria

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• Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats.

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• Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons

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• Large neutral amino acids auto exchange when infused by microdialysis into the rat brain: implication for maple syrup urine disease and phenylketonuria.

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• The Metabolic and Molecular Bases of Inherited Disease

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• Pharmacological evidence that α-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats

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• Propionic and L‐methylmalonic acids induce oxidative stress in brain of young rats

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• Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease.

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• Preconditioning Prevents the Inhibition of Na+,K+-ATPase Activity after Brain Ischemia

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• Alanine Prevents the Decrease of Na+,K+-ATPase Activity in Experimental Phenylketonuria

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• KINETICS OF ALANINE REVERSAL ON THE INHIBITION OF NA+, K+-ATPASE ACTIVITY BY PHENYLALANINE AND PHENYLLACTATE IN THE SYNAPTIC PLASMA MEMBRANE FROM THE CEREBRAL CORTEX OF RATS

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• On the Mechanism of Ouabain‐Induced Release of Acetylcholine from Synaptosomes

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• The Relationship between the Branched Chain Amino Acids and Their α-Ketoacids in Maple Syrup Urine Disease

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• CONTROL OF PYRUVATE AND β‐HYDROXYBUTYRATE UTILIZATION IN RAT BRAIN MITOCHONDRIA AND ITS RELEVANCE TO PHENYLKETONURIA AND MAPLE SYRUP URINE DISEASE

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• Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation.

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• CHANGES IN THE AMINO ACID COMPOSITION OF PROTEOLIPIDS OF WHITE MATTER DURING MATURATION OF THE HUMAN NERVOUS SYSTEM *

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• MAPLE SYRUP URINE DISEASE, WITH PARTICULAR REFERENCE TO DIETOTHERAPY.

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• Donepezil treatment mitigates cholinergic system alterations, oxidative stress, neuroinflammation and memory impairment induced by branched-chain amino acid administration in rats.

  2024cites this paper
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• Brain Damage - Bridging Between Basic Research and Clinics

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• Neuropsychiatric and neurochemical sequelae of Maple Syrup Urine Disease

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• Behavioral and neurochemical effects of proline

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• Na,K-ATPase Activity Regulates AMPA Receptor Turnover through Proteasome-Mediated Proteolysis

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