Abnormal expression of ATP1A1 and ATP1A2 in breast cancer

Breast cancer is the first in incidence and the second in death among all solid tumors occurring in women. The identification of molecular genetic abnormalities in breast cancer is important to improve the results of treatment. In the present study, we analyzed microarray data of breast cancer expression profiling (NCBI GEO database, accession GSE65194), focusing on Na +/K +-ATPase coding genes. We found overexpression of the ATP1A1 and down-regulation of the ATP1A2. We expect that our research could help to improve the understanding of predictive and prognostic features of breast cancer.

• Publication year

  2017

• Venue

  F1000Research

• Publication date

  2017-01-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.12688/f1000research.10481.1PMID 28529692PMCID 5428514
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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