A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Cancer Chemotherapy and Pharmacology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Mathematics

• Identifiers
  DOI 10.1007/s002800050039PMID 10755313
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bootstrap resampling: a powerful method of assessing confidence intervals for doses from experimental data

  1999cited by this paper
• Empirical nonparametric bootstrap strategies in quantitative trait loci mapping: conditioning on the genetic model.

  1998cited by this paper
• Resampling methods in sparse sampling situations in preclinical pharmacokinetic studies.

  1998cited by this paper
• Biostatistical Analysis, 3rd edn.

  1996cited by this paper
• Design and analysis of in vitro antitumor pharmacodynamic studies.

  1995cited by this paper
• Pharmacodynamics of mitomycin C in cultured human bladder tumors.

  1991cited by this paper
• Evaluation of arylmethylaminopropanediols by a novel in vitro pharmacodynamic assay: correlation with antitumor activity in vivo.

  1990cited by this paper
• New colorimetric cytotoxicity assay for anticancer-drug screening.

  1990cited by this paper
• In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator.

  1989cited by this paper

• Influence of electric field, blood velocity and pharmacokinetic on electrochemotherapy efficiency.

  2023cites this paper
• In silico study about the influence of electroporation parameters on the cellular internalization, spatial uniformity, and cytotoxic effects of chemotherapeutic drugs using the Method of Fundamental Solutions

  2023cites this paper
• Influence of electric pulse characteristics on the cellular internalization of chemotherapeutic drugs and cell survival fraction in electroporated and vasoconstricted cancer tissues using boundary element techniques

  2023cites this paper
• Mahonia aquifolium Extracts Promote Doxorubicin Effects against Lung Adenocarcinoma Cells In Vitro

  2020cites this paper
• Development of a Subcellular Semimechanism-Based Pharmacokinetic/Pharmacodynamic Model to Characterize Paclitaxel Effects Delivered by Polymeric Micelles.

  2019cites this paper
• Chemotherapeutic dosing implicated by pharmacodynamic modeling of in vitro cytotoxic data: a case study of paclitaxel

  2017cites this paper
• Poly(l-γ-glutamylglutamine) Polymer Enhances Doxorubicin Accumulation in Multidrug Resistant Breast Cancer Cells

  2016cites this paper
• To evaluate the effect of formulation of Nanoarchaeosomal 6-gingerol on the growth of breast cancer MCF-7 cell line

  2015cites this paper
• Label-free isolation of a prostate cancer cell among blood cells and the single-cell measurement of drug accumulation using an integrated microfluidic chip.

  2015cites this paper
• Alternative Models in Drug Discovery and Development Part I: In Silico and In Vitro Models

  2014cites this paper
• Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.

  2013cites this paper
• Modeling of human tumor xenografts and dose rationale in oncology.

  2013cites this paper
• The Valley of Death in anticancer drug development: a reassessment.

  2012cites this paper
• Dual-effect laser handpiece for modification of tissue permeability

  2011cites this paper
• Reversal of multidrug resistance by methoxypolyethylene glycol-block-polycaprolactone diblock copolymers through the inhibition of P-glycoprotein function.

  2009cites this paper
• A model-based approach to the in vitro evaluation of anticancer activity

  2009cites this paper
• Dynamic Modelling and Prediction of Cytotoxicity on Microelectronic cell Sensor Array

  2008cites this paper
• Cell Cycle Checkpoint Models for Cellular Pharmacology of Paclitaxel and Platinum Drugs

  2008cites this paper
• Kinetic model of drug distribution in the urinary bladder wall following intravesical instillation.

  2006cites this paper
• A Mechanistic Study of Enhanced Doxorubicin Uptake and Retention in Multidrug Resistant Breast Cancer Cells Using a Polymer-Lipid Hybrid Nanoparticle System

  2006cites this paper
• Two-mechanism peak concentration model for cellular pharmacodynamics of Doxorubicin.

  2005cites this paper
• Modeling the Pharmacodynamics of Highly Schedule-Dependent Agents: Exemplified by Cytarabine-Based Regimens in Acute Myeloid Leukemia

  2005cites this paper
• Theoretical Analyses and Simulations of Anticancer Drug Delivery

  2004cites this paper
• In vitro cell growth pharmacodynamic studies: a new nonparametric approach to determining the relative importance of drug concentration and treatment time

  2003cites this paper
• Simulation model of doxorubicin activity in islets of human breast cancer cells.

  2003cites this paper
• Dovepress Open Access to Scientific and Medical Research Open Access Full Text Article Daunorubicin-loaded Magnetic Nanoparticles of Fe 3 O 4 Overcome Multidrug Resistance and Induce Apoptosis of K562-n/vcr Cells in Vivo Jia-hua Ding

  year unknowncites this paper