Synthesis of substituted triazolyl curcumin mimics that inhibit RANKL-induced osteoclastogenesis.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Bioorganic & Medicinal Chemistry Letters

• Publication date

  2011-06-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bmcl.2011.04.106PMID 21570847
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Curcumin improves bone microarchitecture and enhances mineral density in APP/PS1 transgenic mice.

  2011cited by this paper
• Of mice and men: divergent risks of teriparatide-induced osteosarcoma

  2010cited by this paper
• New treatment targets in osteoporosis.

  2010cited by this paper
• Synthesis of sulfonyl curcumin mimics exerting a vasodilatation effect on the basilar artery of rabbits.

  2009cited by this paper
• Future therapeutic targets in osteoporosis

  2009cited by this paper
• Building bone to reverse osteoporosis and repair fractures.

  2008cited by this paper
• Cu-catalyzed azide-alkyne cycloaddition.

  2008cited by this paper
• Synthesis of curcumin mimics with multidrug resistance reversal activities.

  2008cited by this paper
• The biology of osteocytes

  2007cited by this paper
• Reversal of multidrug resistance by 4-chloro-N-(3-((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide through the reversible inhibition of P-glycoprotein.

  2007cited by this paper
• Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks.

  2006cited by this paper
• Synthesis of novel curcumin mimics with asymmetrical units and their anti-angiogenic activity.

  2005cited by this paper
• Pathogenesis of osteoporosis: concepts, conflicts, and prospects.

  2005cited by this paper
• Curcumin (Diferuloylmethane) Inhibits Receptor Activator of NF-κB Ligand-Induced NF-κB Activation in Osteoclast Precursors and Suppresses Osteoclastogenesis1

  2004cited by this paper
• Curcumin (diferuloylmethane) inhibits receptor activator of NF-kappa B ligand-induced NF-kappa B activation in osteoclast precursors and suppresses osteoclastogenesis.

  2004cited by this paper
• Biological Properties of Curcumin-Cellular and Molecular Mechanisms of Action

  2004cited by this paper
• Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.

  2002cited by this paper
• The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro.

  2002cited by this paper
• Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

  2001cited by this paper
• The role of bisphosphonates in breast cancer: Development of bisphosphonates

  2001cited by this paper
• Stimulatory effect of curcumin on osteoclast apoptosis.

  2000cited by this paper
• Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.

  1999cited by this paper
• Estrogens reduce bone loss in the ovariectomized, lactating rat model.

  1991cited by this paper
• Azides: their preparation and synthetic uses

  1988cited by this paper

• Nutraceuticals in orthopedic implant osseointegration: Mechanisms, evidence, and clinical perspectives.

  2026cites this paper
• Nutraceuticals and Functional Foods: A Comprehensive Review of Their Role in Bone Health

  2024cites this paper
• Protective effects of curcumin against osteoporosis and its molecular mechanisms: a recent review in preclinical trials

  2023cites this paper
• Effect of Curcuma longa L. and curcumin on diabetes and it’s complications: A review

  2021cites this paper
• Effect of turmeric extract on bone healing in an experimental model of femoral bone fracture

  2021cites this paper
• Effect of curcumin on bone tissue in the diabetic rat: repair of peri-implant and critical-sized defects.

  2018cites this paper
• Synthesis, surface profile, nonlinear reflective index and photophysical properties of curcumin compound

  2018cites this paper
• Diethylamino-curcumin mimic with trizolyl benzene enhances TRAIL-mediated cell death on human glioblastoma cells

  2018cites this paper
• Reactive Oxygen Species and Bone Fragility

  2017cites this paper
• Attenuation of Oxidative Stress-Induced Osteoblast Apoptosis by Curcumin is Associated with Preservation of Mitochondrial Functions and Increased Akt-GSK3β Signaling

  2017cites this paper
• Treatment with curcumin alleviates sublesional bone loss following spinal cord injury in rats.

  2015cites this paper
• Attenuation of hind-limb suspension-induced bone loss by curcumin is associated with reduced oxidative stress and increased vitamin D receptor expression

  2015cites this paper
• Synthesis of alkylsulfonyl and substituted benzenesulfonyl curcumin mimics as dual antagonist of L-type Ca(2+) channel and endothelin A/B2 receptor.

  2015cites this paper
• Recent developments in chemistry and biology of curcumin analogues

  2014cites this paper
• The TRAIL Sensitization Effect of Substituted Triazolyl Curcumin Mimics Against Brain Cancer Cells

  2014cites this paper
• Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling

  2014cites this paper
• Synthesis of diethylamino-curcumin mimics with substituted triazolyl groups and their sensitization effect of TRAIL against brain cancer cells.

  2014cites this paper
• Cytotoxicity of Substituted Benzimidazolyl Curcumin Mimics Against Multi-Drug Resistance Cancer Cell

  2013cites this paper
• Therapeutic Advantages of Treatment of High-Dose Curcumin in the Ovariectomized Rat

  2013cites this paper
• Synthesis of Curcumin Mimics Library with α,β-Unsaturated Carbonyl Aromatic Group and their Inhibitory Effect against Adipocyte Differentiation of 3T3-L1

  2013cites this paper
• Synthesis of 7,8-epi-Valtrate from (+)-Genipin

  2012cites this paper
• Synthesis of substituted benzimidazolyl curcumin mimics and their anticancer activity.

  2012cites this paper
• Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes

  2012cites this paper
• A synergistic bone sparing effect of curcumin and alendronate in ovariectomized rat

  2012influential citation