Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Blood

• Publication date

  2013-07-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/blood-2012-11-459347PMID 23690447PMCID PMC3701902
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Macrophage regulation of tumor responses to anticancer therapies.

  2013cited by this paper
• Reversing resistance to vascular-disrupting agents by blocking late mobilization of circulating endothelial progenitor cells.

  2012cited by this paper
• Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

  2012cited by this paper
• TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice.

  2011cited by this paper
• DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo.

  2011cited by this paper
• Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy.

  2011influential reference
• Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids.

  2011cited by this paper
• Bone Marrow-Derived Endothelial Progenitors Expressing Delta-Like 4 (Dll4) Regulate Tumor Angiogenesis

  2011cited by this paper
• Peering into the aftermath: The inhospitable host?

  2010cited by this paper
• Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors.

  2010cited by this paper
• Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction.

  2010cited by this paper
• Bone marrow is a reservoir for proangiogenic myelomonocytic cells but not endothelial cells in spontaneous tumors.

  2010cited by this paper
• Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma.

  2010cited by this paper
• Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

  2010cited by this paper
• C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

  2010cited by this paper
• Late release of circulating endothelial cells and endothelial progenitor cells after chemotherapy predicts response and survival in cancer patients.

  2010cited by this paper
• Targeting Notch signaling pathway to overcome drug resistance for cancer therapy.

  2010cited by this paper
• gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

  2009cited by this paper
• Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.

  2009cited by this paper
• Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.

  2009cited by this paper
• Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells.

  2008cited by this paper
• Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells.

  2008cited by this paper
• Fate tracing reveals the endothelial origin of hematopoietic stem cells.

  2008influential reference
• Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.

  2008cited by this paper
• Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

  2008cited by this paper
• Notch Pathway Modulation on Bone Marrow-Derived Vascular Precursor Cells Regulates Their Angiogenic and Wound Healing Potential

  2008cited by this paper
• Notch signaling in blood vessels: who is talking to whom about what?

  2007cited by this paper
• Notch Signaling, γ-Secretase Inhibitors, and Cancer Therapy: Figure 1.

  2007cited by this paper
• Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals.

  2007cited by this paper
• Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization.

  2007cited by this paper
• Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells

  2007cited by this paper
• Notch signaling, gamma-secretase inhibitors, and cancer therapy.

  2007cited by this paper
• VE‐cadherin‐CreERT2 transgenic mouse: A model for inducible recombination in the endothelium

  2006cited by this paper
• VE‐Cadherin‐Cre‐recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells

  2006cited by this paper
• Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors.

  2006cited by this paper
• Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

  2006cited by this paper
• Myeloid lineage progenitors give rise to vascular endothelium

  2006cited by this paper
• The multifaceted circulating endothelial cell in cancer: towards marker and target identification

  2006cited by this paper
• Contribution of bone marrow–derived endothelial cells to human tumor vasculature

  2005cited by this paper
• Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

  2005cited by this paper
• VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

  2005cited by this paper
• Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

  2004cited by this paper
• Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors.

  2003cited by this paper
• Accelerated regrowth of non-small-cell lung tumours after induction chemotherapy

  2003cited by this paper
• Role of bone marrow-derived cells in tumor angiogenesis and treatment.

  2003cited by this paper
• Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

  2001influential reference
• Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

  2001cited by this paper
• Notch signaling is essential for vascular morphogenesis in mice.

  2000cited by this paper
• Deficient T cell fate specification in mice with an induced inactivation of Notch1.

  1999cited by this paper
• Generalized lacZ expression with the ROSA26 Cre reporter strain

  1999cited by this paper
• Rapid tumor cell proliferation after induction chemotherapy in oropharyngeal cancer

  1994cited by this paper

• Macrophages in tumor cell migration and metastasis

  2024cites this paper
• Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of NOTCH1 p.E450K

  2023cites this paper
• Quenching Thirst with Poison? Paradoxical Effect of Anticancer Drugs.

  2023cites this paper
• Chemotherapy-induced metastasis: molecular mechanisms and clinical therapies

  2023influential citation
• A Proposed Link Between Acute Thymic Involution and Late Adverse Effects of Chemotherapy

  2022cites this paper
• Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models

  2022cites this paper
• Ceramide launches an acute anti‐adhesion pro‐migration cell signaling program in response to chemotherapy

  2020cites this paper
• Effect of psychological counseling plus meticulous care on posttraumatic growth and social support of patients with breast cancer undergoing chemotherapy

  2020cites this paper
• G protein‐coupled oestrogen receptor promotes cell growth of non‐small cell lung cancer cells via YAP1/QKI/circNOTCH1/m6A methylated NOTCH1 signalling

  2020cites this paper
• Monocytes and Macrophages in Cancer: Unsuspected Roles.

  2020cites this paper
• Chemotherapy-Induced Metastasis: Molecular Mechanisms, Clinical Manifestations, Therapeutic Interventions.

  2019cites this paper
• The emerging roles of macrophages in cancer metastasis and response to chemotherapy

  2019cites this paper
• TLR4-Induced Inflammation Is a Key Promoter of Tumor Growth, Vascularization, and Metastasis

  2019cites this paper
• Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell Carcinoma

  2019cites this paper
• Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy

  2019cites this paper
• CMAR_A_220327 10791..10800

  2019cites this paper
• Chemotherapy-induced metastasis: mechanisms and translational opportunities

  2018cites this paper
• The role of Notch signaling pathway in cisplatin sensitivity and radiation sensitivity in head and neck squamous cell carcinoma

  2018cites this paper
• CCL2 Is a Vascular Permeability Factor Inducing CCR2-Dependent Endothelial Retraction during Lung Metastasis

  2018cites this paper
• Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

  2017cites this paper
• Chemotherapy-induced metastasis in breast cancer

  2017cites this paper
• Efficacy of cisplatin/pemetrexed with bevacizumab to treat advanced lung adenocarcinoma with different drive genes: case report and literature review

  2016cites this paper
• Efficacy of Addition of Antiangiogenic Agents to Taxanes-Containing Chemotherapy in Advanced Nonsmall-Cell Lung Cancer

  2015cites this paper
• Mechanisms and Modulation of Tumor Microenvironment-Induced Immune Resistance

  2015cites this paper
• Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy.

  2015cites this paper
• The Role of TLR4 in Chemotherapy-Driven Metastasis.

  2015cites this paper
• CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies

  2014cites this paper
• Are natural killer cells superior CAR drivers?

  2014cites this paper