Up‐regulation of NMDAR1 subunit gene expression in cortical neurons via a PKA‐dependent pathway

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neurochemistry

• Publication date

  2004-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1471-4159.2003.02156.xPMID 14720206
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Signaling from cAMP/PKA to MAPK and synaptic plasticity

  2003cited by this paper
• Patterned Vision Causes CRE-Mediated Gene Expression in the Visual Cortex through PKA and ERK

  2003influential reference
• Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

  2002cited by this paper
• Nerve Growth Factor Uses Ras/ERK and Phosphatidylinositol 3-Kinase Cascades to Up-regulate theN-Methyl-d-aspartate Receptor 1 Promoter*

  2001cited by this paper
• An initiator element mediates autologous downregulation of the human type A gamma -aminobutyric acid receptor beta 1 subunit gene.

  2000cited by this paper
• CREB: a message to remember

  1999cited by this paper
• Widespread up-regulation of N-methyl-D-aspartate receptors after focal photothrombotic lesion in rat brain.

  1999cited by this paper
• Hippocampal N‐methyl‐D‐aspartate receptor subunit mRNA levels in temporal lobe epilepsy patients

  1999cited by this paper
• Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.

  1999cited by this paper
• Characterization of absence seizure-dependent cyclic AMP responsive element-and activator protein 1 DNA-binding activities in lethargic (lh/lh) mice.

  1999cited by this paper
• Upregulation of NMDA Receptors in Hippocampus and Cortex in the Pentylenetetrazol-Induced “Kindling” Model of Epilepsy

  1999cited by this paper
• Nuclear calcium-activated gene expression: possible roles in neuronal plasticity and epileptogenesis.

  1999cited by this paper
• Inducible binding of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein (CREB) to a cAMP-responsive promoter in vivo.

  1999influential reference
• Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesis

  1998cited by this paper
• A role for NMDA-receptor channels in working memory

  1998cited by this paper
• Phosphorylation of the cAMP response element binding protein CREB by cAMP-dependent protein kinase A and glycogen synthase kinase-3 alters DNA-binding affinity, conformation, and increases net charge.

  1998cited by this paper
• CREB and memory.

  1998cited by this paper
• Stress-induced transcriptional regulation in the developing rat brain involves increased cyclic adenosine 3',5'-monophosphate-regulatory element binding activity.

  1997cited by this paper
• Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

  1996cited by this paper
• Transcriptional induction of the human renin gene by cyclic AMP requires cyclic AMP response element-binding protein (CREB) and a factor binding a pituitary-specific trans-acting factor (Pit-1) motif.

  1996cited by this paper
• Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

  1996influential reference
• Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation: implications for schizophrenia.

  1996cited by this paper
• N-methyl-D-aspartate receptors activate transcription of c-fos and NGFI-A by distinct phospholipase A2-requiring intracellular signaling pathways.

  1995cited by this paper
• Transcription factors responsive to cAMP.

  1995cited by this paper
• Memories of NMDA receptors and LTP

  1995cited by this paper
• Stress-induced changes in messenger RNA levels of N-methyl-D-aspartate and AMPA receptor subunits in selected regions of the rat hippocampus and hypothalamus.

  1995cited by this paper
• Functional Analysis of the Proximal 5′-Flanking Region of the N-Methyl-D-aspartate Receptor Subunit Gene, NMDAR1 (*)

  1995cited by this paper
• N-methyl-D-aspartic acid receptor messenger ribonucleic acid levels and luteinizing hormone release in immature female rats: effects of stage of pubertal development and exposure to ethanol.

  1995cited by this paper
• N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons.

  1995cited by this paper
• AP-1 and CRE DNA binding activities in rat brain following pentylenetetrazole induced seizures.

  1994cited by this paper
• A synaptic model of memory: long-term potentiation in the hippocampus

  1993cited by this paper
• Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

  1993cited by this paper
• Cloning and analysis of the 5' flanking sequence of the rat N-methyl-D-aspartate receptor 1 (NMDAR1) gene.

  1993cited by this paper
• Calcium regulation of immediate early gene transcription.

  1992cited by this paper
• Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.

  1992influential reference
• Silencing the type II sodium channel gene: a model for neural-specific gene regulation.

  1992cited by this paper
• Excitotoxic cell death.

  1992cited by this paper
• A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells.

  1992cited by this paper
• CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases.

  1991influential reference
• Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells.

  1991cited by this paper
• Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

  1990cited by this paper
• Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

  1989cited by this paper
• Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.

  1989cited by this paper
• Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activation.

  1988cited by this paper
• N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture.

  1988cited by this paper
• Stimulation of the N-methyl-D-aspartate receptor has a trophic effect on differentiating cerebellar granule cells.

  1988cited by this paper
• Ionic dependence of glutamate neurotoxicity

  1987cited by this paper
• Intracellular injections of EGTA block induction of hippocampal long-term potentiation

  1983influential reference
• Forskolin requires more than the catalytic unit to activate adenylate cyclase.

  1982cited by this paper
• Activation of Cyclic AMP‐Generating Systems in Brain Membranes and Slices by the Diterpene Forskolin: Augmentation of Receptor‐Mediated Responses

  1982cited by this paper
• Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

  1981cited by this paper

• Novel molecular insights into the role of CRH type 1 receptor in the pathophysiology of depression.

  2025cites this paper
• Pharmacological inhibition of NMDA receptors reduces migration and viability in triple-negative inflammatory breast cancer cell lines

  2025cites this paper
• A brain-accessible peptide modulates stroke inflammatory response and neurotoxicity by targeting BDNF-receptor TrkB-T1 specific interactome

  2025cites this paper
• Activity-Dependent Nr4a2 Induction Modulates Synaptic Expression of AMPA Receptors and Plasticity via a Ca2+/CRTC1/CREB Pathway

  2023cites this paper
• Oxycodone, an opioid like the others?

  2023cites this paper
• Real‐Time, In Vivo Measurement of Protein Kinase A Activity in Deep Brain Structures Using Fluorescence Lifetime Photometry (FLiP)

  2021cites this paper
• Transcriptional control of synaptic components by the clock machinery

  2020cites this paper
• Cell-type specific asynchronous modulation of PKA by dopamine in learning

  2020cites this paper
• Prevention of excitotoxicity‐induced processing of BDNF receptor TrkB‐FL leads to stroke neuroprotection

  2019cites this paper
• Cell-type specific asynchronous modulation of PKA by dopamine during reward based learning

  2019cites this paper
• Monitoring Behaviorally Induced Biochemical Changes Using Fluorescence Lifetime Photometry

  2019cites this paper
• Effects of intravenous anesthetics on the phosphorylation of cAMP response element‑binding protein in hippocampal slices of adult mice.

  2018cites this paper
• Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice

  2018cites this paper
• Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.

  2017cites this paper
• The role and mechanism of glutamic NMDA receptor in the mechanical hyperalgesia in diabetic rats

  2017cites this paper
• Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease

  2017cites this paper
• Chemokine receptor CXCR4 regulates CaMKII/CREB pathway in spinal neurons that underlies cancer-induced bone pain

  2017cites this paper
• Eliminação de neurônios infragranulares afeta a especificação de neurônios granulares e supragranulares do córtex cerebral em desenvolvimento

  2017cites this paper
• Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions.

  2017cites this paper
• Activity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Development

  2016cites this paper
• Memory/Learning, Dementia, and Kampo

  2016cites this paper
• Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice.

  2016cites this paper
• Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII–CREB and Astroglial JAK2–STAT3 Cascades in Mice

  2015cites this paper
• CDRI-08 Attenuates REST/NRSF-Mediated Expression of NMDAR1 Gene in PBDE-209-Exposed Mice Brain

  2015cites this paper
• Activity-dependent gene regulation in neurons: energy coupling and a novel biosensor

  2015cites this paper
• Pratensein attenuates Aβ-induced cognitive deficits in rats: enhancement of synaptic plasticity and cholinergic function.

  2015cites this paper
• Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice.

  2015cites this paper
• Aβ’s effect on long term memory: a top-down approach in Lymnaea stagnalis

  2015cites this paper
• Activation of spinal GABAB receptors normalizes N-methyl-D-aspartate receptor in diabetic neuropathy.

  2014cites this paper
• Antidepressant-like effect of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action.

  2014cites this paper
• Protective effect of Millettia pulchra polysaccharide on cognitive impairment induced by D-galactose in mice.

  2014cites this paper
• Social Isolation Stress-Induced Fear Memory Deficit is Mediated by Down-Regulated Neuro-Signaling System and Egr-1 Expression in the Brain

  2014cites this paper
• Long-term ginsenoside Rg1 supplementation improves age-related cognitive decline by promoting synaptic plasticity associated protein expression in C57BL/6J mice.

  2014cites this paper
• Protective effect of madecassoside against cognitive impairment induced by D-galactose in mice.

  2014cites this paper
• Kampo formulations, chotosan, and yokukansan, for dementia therapy: existing clinical and preclinical evidence.

  2013cites this paper
• Molecular Mechanisms of Environmental Enrichment: Impairments in Akt/GSK3β, Neurotrophin-3 and CREB Signaling

  2013cites this paper
• Synaptic plasticity in depression: molecular, cellular and functional correlates.

  2013cites this paper
• Bacopa monnieri Ameliorates Memory Deficits in Olfactory Bulbectomized Mice: Possible Involvement of Glutamatergic and Cholinergic Systems

  2013cites this paper
• Receptor to glutamate NMDA-type: the functional diversity of the nr1 isoforms and pharmacological properties.

  2013cites this paper
• Polycomblike protein PHF1b: a transcriptional sensor for GABA receptor activity

  2013cites this paper
• Intrathecal administration of cyclic AMP response element-binding protein-antisense oligonucleotide attenuates neuropathic pain after peripheral nerve injury and decreases the expression of N-methyl-D-aspartic receptors in mice.

  2013influential citation
• Neurobiological and pharmacological validity of curcumin in ameliorating memory performance of senescence-accelerated mice.

  2013cites this paper
• Beneficial effects of asiaticoside on cognitive deficits in senescence-accelerated mice.

  2013cites this paper
• Impaired Transcription in Alzheimer's Disease: Key Role in Mitochondrial Dysfunction and Oxidative Stress

  2013cites this paper
• Estructura y función de las subunidades del receptor a glutamato tipo NMDA

  2012cites this paper
• Modulation of Alzheimer's Disease Pathology and Neuroplasticity by Environmental Factors

  2012cites this paper
• Ethanol Activation of Protein Kinase A Regulates GABAA Receptor Subunit Expression in the Cerebral Cortex and Contributes to Ethanol-Induced Hypnosis

  2012cites this paper
• [Structure and function of NMDA-type glutamate receptor subunits].

  2012cites this paper
• Brain‐derived neurotrophic factor uses CREB and Egr3 to regulate NMDA receptor levels in cortical neurons

  2012cites this paper
• Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain

  2011cites this paper
• Ephrin-A5 and EphA5 Interaction Induces Synaptogenesis during Early Hippocampal Development

  2010cites this paper
• Neuroprotective Effect of Inhaled Nitric Oxide on Excitotoxic-Induced Brain Damage in Neonatal Rat

  2010cites this paper
• Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain.

  2010cites this paper
• Calcitonin gene‐related peptide as a regulator of neuronal CaMKII–CREB, microglial p38–NF&kgr;B and astroglial ERK–Stat1/3 cascades mediating the development of tolerance to morphine‐induced analgesia

  2010cites this paper
• Effects of sex steroids on spatial cognition in the zebra finch (Taeniopygia guttata)

  2010cites this paper
• Long-term ginsenoside consumption prevents memory loss in aged SAMP8 mice by decreasing oxidative stress and up-regulating the plasticity-related proteins in hippocampus.

  2009cites this paper
• Long-term ginsenoside administration prevents memory impairment in aged C57BL/6J mice by up-regulating the synaptic plasticity-related proteins in hippocampus.

  2009cites this paper
• Transcriptional Regulation of NMDA Receptor Expression

  2009cites this paper
• Role of the brain‐derived neurotrophic factor at glutamatergic synapses

  2008influential citation
• The role of transcription factors cyclic-AMP responsive element modulator (CREM) and inducible cyclic-AMP early repressor (ICER) in epileptogenesis.

  2008cites this paper
• Manganese Superoxide Dismutase Contributes to Cisplatin-Induced Cytotoxicity Rather than All- Trans Retinoic Acid-Dependent Chemoresistance

  2008cites this paper
• All-trans-retinoic acid induces manganese superoxide dismutase in human neuroblastoma through NF-kappaB.

  2008cites this paper
• BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation

  2008cites this paper
• Post-training intrahippocampal infusion of nicotine-bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats.

  2007cites this paper
• BDNF regulates the expression and traffic of NMDA receptors in cultured hippocampal neurons.

  2007cites this paper
• Paradoxical Facilitatory Effect of Low-Dose Alcohol Consumption on Memory Mediated by NMDA Receptors

  2007cites this paper
• Studio dell'effetto delle radiazioni non ionizzanti sul processo di maturazione e differenziamento dei granuli cerebellari di ratto neonato: studi in vitro e in vivo

  2006cites this paper
• Sex‐ and cell‐type‐specific patterns of GABAA receptor and estradiol‐mediated signaling in the immature rat substantia nigra

  2006cites this paper
• Neuregulin Signaling and GABA A Receptor Expression in Cerebellar Granule Neurons

  2006cites this paper
• Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases.

  2006cites this paper
• Potential Role of cAMP Response Element-Binding Protein in Ethanol-Induced N-Methyl-d-aspartate Receptor 2B Subunit Gene Transcription in Fetal Mouse Cortical Cells

  2005cites this paper
• Lead neurotoxicity: from exposure to molecular effects.

  2005cites this paper
• Histone methylation at gene promoters is associated with developmental regulation and region‐specific expression of ionotropic and metabotropic glutamate receptors in human brain

  2005cites this paper
• Potential Role of CREB in Ethanol-induced NR 2 B Gene Transcription in Fetal Mouse Cortical Cells

  2005cites this paper
• Transcription of the NR1 Subunit of the N-Methyl-d-aspartate Receptor Is Down-regulated by Excitotoxic Stimulation and Cerebral Ischemia *

  2005cites this paper
• The role of NMDA receptor upregulation in phencyclidine-induced cortical apoptosis in organotypic culture.

  2005cites this paper
• Glutamate-associated plasticity in the ventral tegmental area is necessary for conditioning environmental stimuli with morphine.

  2004cites this paper
• Development/plasticity/repair Camp Response Element-binding Protein Regulates Differentiation and Survival of Newborn Neurons in the Olfactory Bulb

  year unknowncites this paper