Characterization of the biological antioxidant potential in the vitreous fluid from patients with rhegmatogenous retinal detachment

Atsuko Maeno,Yukihiko Suzuki,Kobu Adachi,S. Takahashi,Y. Yokoi,M. Nakazawa

Published 2016 in Acta ophthalmologica

ABSTRACT

pressure (r = 0.412, p = 0.042), and the normal saline guttae were correlated not with the opening pressure (r = 0.387, p = 0.101), but rather with the reopening pressure (r = 0.874, p < 0.001). Among the 19 patients, tube ligation (Kee 2001) was performed simultaneously with AGV implantation in two patients due to an intraoperative shallow anterior chamber. In another 17 patients, excluding the above two patients with tube ligation (mean age, 52.9 17.7 years; 13 men, four women; preoperative mean IOP, 41.8 9.5 mmHg; day 1 postoperative mean IOP, 9.6 5.4 mmHg) the reopening pressure and day 1 postoperative IOP showed a strong positive correlation (r = 0.715, p = 0.001) and the normal saline guttae correlated negatively with the day 1 postoperative IOP (Pearson’s correlation, r = 0.74 2, p = 0.001). Among the five patients with low (level-1) reopening pressure, four patients (80%) experienced hypotonic maculopathy (n = 1), shallow anterior chamber (n = 2) or choroidal effusion (n = 1). Hypotonic maculopathy and choroidal effusion regressed spontaneously. However, in two cases of anterior chamber shallowing, viscoelastic injection was required to resolve an iridocorneal touch. We suggest that careful subjective grading of the reopening pressure (when priming the tube) by an experienced surgeon is helpful in predicting early postoperative hypotonic complications. In addition, tube ligation may be useful to prevent hypotony-associated complications (Kee 2001). To confirm this possibility, a study with a larger patient population is necessary.

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