Modulation of airway hyperresponsiveness and eosinophilia by selective histamine and 5‐HT receptor antagonists in a mouse model of allergic asthma

No abstract is available for this paper.

• Publication year

  1998

• Venue

  British Journal of Pharmacology

• Publication date

  1998-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.bjp.0701901PMID 9692769PMCID PMC1565459
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994influential reference
• Role of cytokines in bronchial hyperresponsiveness.

  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
• Mucosal inflammation in asthma.

  1990cited by this paper
• Effect of ketanserin, a new blocking agent of the 5‐HT2 receptor, on airway responsiveness in asthma

  1990cited by this paper
• The role of histamine in allergic diseases.

  1990cited by this paper
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  1989cited by this paper
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  1989influential reference
• Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

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  1987cited by this paper
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  1986cited by this paper
• Histamine augments interleukin-2 production and the activation of cytotoxic T lymphocytes.

  1986cited by this paper
• Histamine and immune modulation.

  1983cited by this paper
• Histamine and immune modulation.

  1983influential reference
• Modulation of lymphocyte migration by human lymphokines. II. Purification of a lymphotactic factor (LCF).

  1982cited by this paper
• Induction of adjuvant-independent IgE responses in inbred mice: primary, secondary, and persistent IgE responses to ovalbumin and ovomucoid.

  1981cited by this paper

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  2000cites this paper
• Paracetamol and asthma

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