Downregulation of estrogen‐metabolizing 17β‐hydroxysteroid dehydrogenase Type 2 expression correlates inversely with Ki67 proliferation marker in colon‐cancer development

No abstract is available for this paper.

• Publication year

  2002

• Venue

  International Journal of Cancer

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ijc.1567PMID 11774236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Colonic mucin-carbohydrate components in colorectal tumors and their possible relationship to MUC2, p53 and DCC immunoreactivities.

  2000cited by this paper
• Oestrogen inactivation in the colon: analysis of the expression and regulation of 17 β -hydroxysteroidehydrogenase isozymes in normal colon and colonic cancer

  2000cited by this paper
• Selective loss of estrogen receptor β in malignant human colon

  2000cited by this paper
• Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease.

  2000cited by this paper
• 17β-Hydroxysteroid Dehydrogenase Type 1 and 2 Expression in the Human Fetus1

  2000cited by this paper
• Selective loss of estrogen receptor beta in malignant human colon.

  2000cited by this paper
• Inactivation of the Peroxisomal Multifunctional Protein-2 in Mice Impedes the Degradation of Not Only 2-Methyl-branched Fatty Acids and Bile Acid Intermediates but Also of Very Long Chain Fatty Acids*

  2000cited by this paper
• 17beta-hydroxysteroid dehydrogenase type 1 and 2 expression in the human fetus.

  2000cited by this paper
• Functional Estrogen Receptor in Colon Cancer Cells

  1999cited by this paper
• Functional estrogen receptor beta in colon cancer cells.

  1999cited by this paper
• Characterization of molecular and catalytic properties of intact and truncated human 17beta-hydroxysteroid dehydrogenase type 2 enzymes: intracellular localization of the wild-type enzyme in the endoplasmic reticulum.

  1999cited by this paper
• 17Beta-hydroxysteroid dehydrogenases in normal human mammary epithelial cells and breast tissue.

  1999cited by this paper
• 17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes.

  1999cited by this paper
• Loss of estrogen inactivation in colonic cancer.

  1999cited by this paper
• Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis.

  1999cited by this paper
• Human 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression and localization in term placenta and in endometrium during the menstrual cycle.

  1998cited by this paper
• Clinical review 92: Phytoestrogens.

  1998cited by this paper
• Mouse 17 beta-hydroxysteroid dehydrogenase type 2 mRNA is predominantly expressed in hepatocytes and in surface epithelial cells of the gastrointestinal and urinary tracts.

  1998cited by this paper
• Human 17β-Hydroxysteroid Dehydrogenase Type 2 Messenger Ribonucleic Acid Expression and Localization in Term Placenta and in Endometrium during the Menstrual Cycle1

  1998cited by this paper
• Physiology and molecular genetics of 17 beta-hydroxysteroid dehydrogenases.

  1997cited by this paper
• Differential expression patterns of the PEA3 group transcription factors through murine embryonic development

  1997cited by this paper
• Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.

  1997cited by this paper
• Thapsigargin-induced gene expression in nonexcitable cells is dependent on calcium influx.

  1997cited by this paper
• Molecular endocrinology of hydroxysteroid dehydrogenases.

  1997cited by this paper
• Phyto-oestrogens and Western diseases.

  1997cited by this paper
• Review of the estrogenic and antiestrogenic activity of polycyclic aromatic hydrocarbons: relationship to carcinogenicity.

  1997cited by this paper
• Physiology and molecular genetics of 17β-hydroxysteroid dehydrogenases

  1997cited by this paper
• Estradiol activation of human colon carcinoma-derived Caco-2 cell growth.

  1996cited by this paper
• Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

  1996cited by this paper
• REVIEW ARTICLE. MUCUS GLYCOPROTEINS AND THEIR ROLE IN COLORECTAL DISEASE

  1996cited by this paper
• Postmenopausal hormone use and risk of large-bowel cancer.

  1995cited by this paper
• Principles of pharmacology : basic concepts and clinical applications

  1995cited by this paper
• Estrogen replacement therapy and risk of fatal colon cancer in a prospective cohort of postmenopausal women.

  1995cited by this paper
• Estrogen receptor-mediated direct stimulation of colon cancer cell growth in vitro.

  1994cited by this paper
• Aberrant accumulation of p53 associates with Ki67 and mitotic count in benign skin lesions

  1994cited by this paper
• 17 beta-Hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium.

  1994cited by this paper
• Colorectal mucin histochemistry in health and disease: A critical review

  1994cited by this paper
• Characterization of 17 beta-hydroxysteroid dehydrogenase type 1 in choriocarcinoma cells: regulation by basic fibroblast growth factor.

  1994cited by this paper
• Characterization of 17β-hydroxysteroid dehydrogenase type 1 in choriocarcinoma cells: regulation by basic fibroblast growth factor

  1994cited by this paper
• Expression of 17 beta-hydroxysteroid dehydrogenase in human granulosa cells: correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production.

  1994cited by this paper
• The presence of functional estrogen receptors in intestinal epithelial cells.

  1993cited by this paper
• Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.

  1993cited by this paper
• Fundamental principles of in situ hybridization.

  1993cited by this paper
• Reproductive factors and colon cancers.

  1990cited by this paper
• Immunohistochemical assessment of growth fractions in colorectal adenocarcinomas with monoclonal antibody Ki-67. Relation to clinical and pathological variables.

  1990cited by this paper
• Histological Typing of Intestinal Tumours

  1989cited by this paper
• Genetic alterations during colorectal-tumor development.

  1988cited by this paper
• Biomarkers of increased susceptibility to gastrointestinal cancer: new application to studies of cancer prevention in human subjects.

  1988cited by this paper
• Complete amino acid sequence of human placental 17β‐hydroxysteroid dehydrogenase deduced from cDNA

  1988cited by this paper
• Mucin histochemistry in colonic polyps and cancer.

  1987cited by this paper
• Mechanisms of tumor progression.

  1986cited by this paper
• Colonic mucin glycoproteins in health and disease.

  1986cited by this paper
• Effect of added dietary calcium on colonic epithelial-cell proliferation in subjects at high risk for familial colonic cancer.

  1985cited by this paper
• Large bowel cancer in women in relation to reproductive and hormonal factors: a case-control study.

  1983cited by this paper
• The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today.

  1981cited by this paper
• International Histological Classification of Tumours, No. 15, B.C. Morson, L.H. Sobin, in: Histological Typing of Intestinal Tumours. World Health Organization, Geneva (1976), 66, 134 colour plates. Sw. fr. 80, US$32.00.

  1978cited by this paper
• SPECIFIC STAINING OF SULPHATE GROUPS WITH ALCIAN BLUE AT LOW pH

  1964cited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Human Estrogen Receptor �-Gene Structure, Chromosomal Localization, and Expression Pattern*

  year unknowncited by this paper

• Characterization of the Estrogen Response Helps to Predict Prognosis and Identify Potential Therapeutic Targets in Cholangiocarcinoma

  2022cites this paper
• Relevance of Steroid Biosynthesis, Metabolism and Transport in Pathophysiology and Drug Discovery

  2019cites this paper
• Transcriptome of 17β-hydroxysteroid dehydrogenase type 2 plays both hormone-dependent and hormone-independent roles in MCF-7 breast cancer cells.

  2019cites this paper
• Intracrine Regulation of Estrogen and Other Sex Steroid Levels in Endometrium and Non-gynecological Tissues; Pathology, Physiology, and Drug Discovery

  2018cites this paper
• Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER

  2017cites this paper
• Endocrine therapy inhibits proliferation and migration, promotes apoptosis and suppresses survivin protein expression in colorectal cancer cells

  2017cites this paper
• Activity of Zearalenone in the Porcine Intestinal Tract

  2016cites this paper
• Intestinal steroidogenesis.

  2015cites this paper
• The prognostic impact of lipid biosynthesis-associated markers, HSD17B2 and HMGCS2, in rectal cancer treated with neoadjuvant concurrent chemoradiotherapy

  2015cites this paper
• Zearalenone in the Intestinal Tissues of Immature Gilts Exposed per os to Mycotoxins

  2015cites this paper
• [Gender-specific colorectal cancer: epidemiologic difference and role of estrogen].

  2014cites this paper
• The Sulfatase Pathway for Estrogen Formation: Targets for the Treatment and Diagnosis of Hormone-Associated Tumors

  2013cites this paper
• Age at Menarche and Risk of Colorectal Cancer: A Meta-Analysis

  2013cites this paper
• Oestrogen and colorectal cancer: mechanisms and controversies

  2013cites this paper
• Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1.

  2011cites this paper
• Biochemical and biological evaluation of novel potent coumarin inhibitor of 17β-HSD type 1.

  2011cites this paper
• Reproductive history and risk of colorectal cancer in postmenopausal women.

  2010cites this paper
• Expression of ERα, ERβ and Co-Regulator PELP1/MNAR in Colorectal Cancer: Prognostic Significance and Clinicopathologic Correlations

  2009cites this paper
• Estrone and progesterone inhibit the growth of murine MC38 colon cancer line.

  2009cites this paper
• Postmenopausal Levels of Endogenous Sex Hormones and Risk of Colorectal Cancer

  2009cites this paper
• Estrogen receptor α/β, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?

  2009cites this paper
• Expression of Estrogen Receptor β in Colon Cancer Progression

  2008cites this paper
• Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women.

  2007cites this paper
• Oestradiol and tamoxifen inhibit murine Colon 38 cancer growth and increase the cytotoxic effect of fluorouracil.

  2007cites this paper
• A new polymorphism in the coding region of exon four in HSD17B2 in relation to risk of sporadic and hereditary breast cancer

  2007cites this paper
• New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland.

  2007cites this paper
• Gene expression studies in gastrointestinal pathophysiology and neoplasia

  2006cites this paper
• Lokale Aktivierung und Inaktivierung der Steroidhormone, insbesondere der Sexualhormone

  2006cites this paper
• Effect of dietary estrogens on cellular markers of colon cancer in mice

  2006cites this paper
• Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme.

  2006cites this paper
• Control of cell proliferation by steroids: the role of 17HSDs.

  2006cites this paper
• Proliferative responses to altered 17beta-hydroxysteroid dehydrogenase (17HSD) type 2 expression in human breast cancer cells are dependent on endogenous expression of 17HSD type 1 and the oestradiol receptors.

  2006cites this paper
• 17 β-HYDROXYSTEROID DEHYDROGENASES / 17-KETOSTEROID REDUCTASES ( 17 HSD / KSRS ) IN PROSTATE CANCER

  2005cites this paper
• Enzymes as modulators in malignant transformation.

  2005cites this paper
• Identification and localization of estrogen receptor alpha- and beta-positive cells in adult male and female mouse intestine at various estrogen levels.

  2004cites this paper
• 17 beta-hydroxysteroid dehydrogenases--their role in pathophysiology.

  2004cites this paper
• YAN LI SEX STEROID METABOLISM IN THE PLACENTA AND THE BREAST

  2004cites this paper
• Sex steroid metabolism in the placenta and the breast

  2004cites this paper
• Identifying target genes regulated downstream of Cdx2 by microarray analysis.

  2004cites this paper
• 17β-Hydroxysteroid dehydrogenases—their role in pathophysiology

  2004cites this paper
• Sex steroid hormone metabolism and prostate cancer.

  2004cites this paper
• The role of 17 beta-hydroxysteroid dehydrogenases.

  2004cites this paper
• Identification and localization of estrogen receptor α- and β-positive cells in adult male and female mouse intestine at various estrogen levels

  2004cites this paper
• Sex hormone metabolism in prostate cancer cells during transition to an androgen-independent state.

  2003cites this paper
• Sex steroid hormone metabolism takes place in human ocular cells.

  2003cites this paper
• Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.

  2003cites this paper
• 17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer.

  2003cites this paper
• Sex steroid metabolism in human gastric mucosa: 17 beta-hydroxysteroid dehydrogenase type 2 in normal, inflamed and neoplastic gastric tissues.

  2003cites this paper
• 17 beta-hydroxysteroid dehydrogenases and cancers.

  2002cites this paper
• 17β-Hydroxysteroid dehydrogenases and cancers

  2002cites this paper