SCIENCE@home

Genetic Polymorphisms: A Novel Perspective on Acute Pancreatitis

Yong Chen,Chao-lian Xie,Ran Hu,Cheng-yi Shen,Mei Zeng,C. Wu,Tian-wu Chen,Chen Chen,M. Tang,H. Xue,Zheng-yu Jin,Xiao Ming Zhang

Published 2017 in Gastroenterology Research and Practice

ABSTRACT

Acute pancreatitis (AP) is a complex disease that results in significant morbidity and mortality. For many decades, it has compelled researchers to explore the exact pathogenesis and the understanding of the pathogenesis of AP has progressed dramatically. Currently, premature trypsinogen activation and NF-κB activation for inflammation are two remarkable hypotheses for the mechanism of AP. Meanwhile, understanding of the influence of genetic polymorphisms has resulted in tremendous development in the understanding of the advancement of complex diseases. Now, genetic polymorphisms of AP have been noted gradually and many researchers devote themselves to this emerging area. In this review, we comprehensively describe genetic polymorphisms combined with the latest hypothesis of pathogenesis associated with AP.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-85 of 85 references · Page 1 of 1

CITED BY

Showing 1-7 of 7 citing papers · Page 1 of 1