Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor-mediated kidney fibrosis.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Clinical Investigation

• Publication date

  2014-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI61368PMID 24743144PMCID PMC4001526
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adult renal mesenchymal stem cell-like cells contribute to juxtaglomerular cell recruitment.

  2013cited by this paper
• A Novel Role for Type 1 Angiotensin Receptors on T Lymphocytes to Limit Target Organ Damage in Hypertension

  2012cited by this paper
• Mechanisms of fibrosis: therapeutic translation for fibrotic disease

  2012cited by this paper
• Aberrant Macrophages Mediate Defective Kidney Repair That Triggers Nephritis in Lupus-Susceptible Mice

  2012cited by this paper
• Distinct macrophage phenotypes contribute to kidney injury and repair.

  2011cited by this paper
• A Role for Angiotensin II Type 1 Receptors on Bone Marrow-Derived Cells in the Pathogenesis of Angiotensin II–Dependent Hypertension

  2010cited by this paper
• Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations1

  2009influential reference
• Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy.

  2009cited by this paper
• Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension.

  2008cited by this paper
• Macrophage diversity in renal injury and repair.

  2008cited by this paper
• A primary culture of mouse proximal tubular cells, established on collagen-coated membranes.

  2007cited by this paper
• Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II-induced inflammation.

  2007cited by this paper
• Sustained renal interstitial macrophage infiltration following chronic angiotensin II infusions.

  2007influential reference
• Biochemical and functional characterization of three activated macrophage populations

  2006cited by this paper
• Blockade of CCR2 ameliorates progressive fibrosis in kidney.

  2004cited by this paper
• A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.

  2002cited by this paper
• Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.

  2002cited by this paper
• Immunosuppressive treatment protects against angiotensin II-induced renal damage.

  2002cited by this paper
• Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure.

  2001cited by this paper
• Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.

  2001cited by this paper
• Investigation

  2000cited by this paper
• Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.

  1999cited by this paper
• Role of IL-1 in renal ischemic reperfusion injury.

  1998cited by this paper
• Interactions of transforming growth factor-beta and angiotensin II in renal fibrosis.

  1998cited by this paper
• Sequential changes in renal expression of renin-angiotensin system genes in acute unilateral ureteral obstruction.

  1995cited by this paper
• J Am Soc Nephrol 12: 317–325, 2001 Renal Interstitial Fibrosis Is Reduced in Angiotensin II Type 1a Receptor-Deficient Mice

  year unknowncited by this paper
• Edinburgh Research Explorer Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis Differential Ly-6C expression identi fi es the recruited macrophage phenotype, which orchestrates the regression of murine liver fi brosis

  year unknowncited by this paper

• Immunological Actions of the Renin Angiotensin System

  2026cites this paper
• Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

  2025cites this paper
• The role of M1/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies

  2025cites this paper
• Hypotensive drugs mitigate the high-sodium diet-induced pro-inflammatory activation of mouse macrophages in vivo.

  2024cites this paper
• Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

  2024cites this paper
• CD226 promotes renal fibrosis by regulating macrophage activation and migration.

  2024cites this paper
• Role of angiotensin converting enzyme in pathogenesis associated with immunity in cardiovascular diseases.

  2024cites this paper
• Research Progress of Drug Delivery Systems Targeting the Kidneys

  2024cites this paper
• M1-aminopeptidase family - beyond antigen-trimming activities.

  2023cites this paper
• Novel Concepts in Nephron Sodium Transport: A Physiological and Clinical Perspective.

  2023cites this paper
• Recent Advances in Understanding the Molecular Pathophysiology of Angiotensin II Receptors; Lessons from Cell-Selective Receptor Deletion in Mice.

  2023cites this paper
• Neuroinflammation and peripheral immunity: Focus on ischemic stroke.

  2023cites this paper
• The link between immunity and hypertension in the kidney and heart

  2023cites this paper
• Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell–Mediated T Cell Activation

  2022cites this paper
• Recent findings on the cellular and molecular mechanisms of action of novel food-derived antihypertensive peptides

  2022cites this paper
• A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury.

  2022cites this paper
• Cell‐Specific Actions of the Prostaglandin E‐Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages

  2022cites this paper
• Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model

  2022influential citation
• Genetic Modifications to Alter Blood Pressure Level

  2022cites this paper
• Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice

  2022cites this paper
• The Immune System in Hypertension: a Lost Shaker of Salt 2021 Lewis K. Dahl Memorial Lecture

  2022cites this paper
• Mosaic theory revised: inflammation and salt play central roles in arterial hypertension

  2022cites this paper
• Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury

  2021cites this paper
• Aldehyde dehydrogenase 2 protects against acute kidney injury by regulating autophagy via the Beclin-1 pathway

  2021cites this paper
• Fibrosis, the Bad Actor in Cardiorenal Syndromes: Mechanisms Involved

  2021cites this paper
• Aldehyde dehydrogenase 2 protects against acute kidney injury by regulating autophagy via the Beclin-1 pathway

  2021cites this paper
• Profiling Immune Cells in the Kidney Using Tissue Cytometry and Machine Learning.

  2021cites this paper
• Granulomatous manifestations associated with COVID19 infection: Is there a link between these two diseases?

  2021cites this paper
• Advances in use of mouse models to study the renin-angiotensin system.

  2021cites this paper
• Angiotensin Receptors in the Kidney and Vasculature in Hypertension and Kidney Disease.

  2021cites this paper
• Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion

  2021cites this paper
• Importance of methodology in the evaluation of renal mononuclear phagocytes and analysis of a model of experimental nephritis with Shp1 conditional knockout mice

  2020cites this paper
• Role of inflammatory chemokines in hypertension.

  2020cites this paper
• Correcting the imbalanced protective RAS in COVID-19 with angiotensin AT2-receptor agonists.

  2020cites this paper
• Coronavirus Disease 2019 and Hypertension: The Role of Angiotensin-Converting Enzyme 2 and the Renin-Angiotensin System

  2020cites this paper
• Immunity and Hypertension

  2020cites this paper
• The varying roles of macrophages in kidney injury and repair.

  2020cites this paper
• The transcription factor Twist1 in the distal nephron but not in macrophages propagates aristolochic acid nephropathy.

  2020cites this paper
• Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.

  2019cites this paper
• Stimulating Type 1 Angiotensin Receptors on T Lymphocytes Attenuates Renal Fibrosis.

  2019cites this paper
• Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.

  2019cites this paper
• KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis.

  2019cites this paper
• Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein

  2019cites this paper
• A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T Cell Activation.

  2019cites this paper
• Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review.

  2019cites this paper
• Tumor Necrosis Factor-α in T Lymphocytes Attenuates Renal Injury and Fibrosis During Nephrotoxic Nephritis.

  2019cites this paper
• Brain–kidney interaction: Renal dysfunction following ischemic stroke

  2019cites this paper
• Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention.

  2019cites this paper
• Pathophysiology of Chronic Kidney Disease

  2019cites this paper
• Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage

  2018cites this paper
• Differential Inflammatory Vascular Cytokine Profiles Associated with Angiotensin II Type 1 Receptor Antibodies and Human Leukocyte Antibodies in Pediatric Renal Transplantation

  2018cites this paper
• Salt, Hypertension, and Immunity.

  2018cites this paper
• Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury.

  2018cites this paper
• Angiotensin-converting enzyme in innate and adaptive immunity

  2018cites this paper
• Novel mechanisms of GPCR functions : AT 1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk

  2018cites this paper
• Macrophages under pressure: the role of macrophage polarization in hypertension.

  2018cites this paper
• Novel mechanisms of G-protein-coupled receptors functions: AT1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk.

  2018cites this paper
• Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis.

  2018cites this paper
• Understanding Angiotensin II Type 1 Receptor Signaling in Vascular Pathophysiology.

  2018cites this paper
• RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function

  2018cites this paper
• Advances in understanding the role of angiotensin-regulated proteins in kidney diseases

  2018cites this paper
• Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure

  2018cites this paper
• TGF-β1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA

  2018cites this paper
• No energy wasted in the fight against vascular inflammation.

  2018cites this paper
• Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

  2018cites this paper
• Angiotensin receptor-binding molecule in leukocytes in association with the systemic and leukocyte inflammatory profile.

  2018cites this paper
• Cytokine Profiles Associated With Angiotensin II Type 1 Receptor Antibodies

  2018cites this paper
• Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry.

  2017cites this paper
• Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells

  2017cites this paper
• The role of chemokines in hypertension and consequent target organ damage

  2017cites this paper
• Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury

  2017cites this paper
• Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis

  2017cites this paper
• Macrophages in neuroinflammation: role of the renin-angiotensin-system

  2017cites this paper
• ACE2 and the Homolog Collectrin in the Modulation of Nitric Oxide and Oxidative Stress in Blood Pressure Homeostasis and Vascular Injury

  2017cites this paper
• Tubular epithelial NF-{ kappa } B activity regulates ischemic

  2017cites this paper
• Clinical importance of chemokines and inflammatory cytokines for patient care following percutaneous nephrolithotripsy.

  2017cites this paper
• The ligand-bound thyroid hormone receptor in macrophages ameliorates kidney injury via inhibition of nuclear factor-κB activities

  2017cites this paper
• Immunologic Effects of the Renin-Angiotensin System.

  2017cites this paper
• Role of the Immune System in Hypertension.

  2017cites this paper
• Multifactorial Immune Cell-Based Development of Heart Failure

  2017cites this paper
• The role of macrophages in hypertension and its complications

  2017cites this paper
• TNF/Ang‐II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function

  2016cites this paper
• The Journal of Clinical Investigation

  2016cites this paper
• Interactions Between the Immune and the Renin–Angiotensin Systems in Hypertension

  2016cites this paper
• Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis.

  2016cites this paper
• ACE2/Ang 1-7 axis: A critical regulator of epicardial adipose tissue inflammation and cardiac dysfunction in obesity

  2016cites this paper
• Tubular Epithelial NF-κB Activity Regulates Ischemic AKI.

  2016cites this paper
• C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.

  2016cites this paper
• Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.

  2016cites this paper
• Dendritic Cells and Macrophages: Sentinels in the Kidney.

  2015cites this paper
• Dendritic Cells and Macrophages: Sentinels in the

  2015cites this paper
• Renal Allograft Fibrosis: Biology and Therapeutic Targets

  2015cites this paper
• The effect of angiotensin-(1-7) in mouse unilateral ureteral obstruction.

  2015cites this paper
• Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice.

  2015cites this paper
• Current position of TNF-α in melanomagenesis

  2015cites this paper
• Another chapter in the understanding of angiotensin–catecholamine interactions relevant to blood pressure control

  2014cites this paper
• Class A scavenger receptor deficiency augments angiotensin II-induced vascular remodeling.

  2014cites this paper