DNA structure-specific priming of ATR activation by DNA-PKcs

Sophie Vidal-Eychenié,Chantal Décaillet,J. Basbous,A. Constantinou

Published 2013 in Journal of Cell Biology

ABSTRACT

The juxtaposition of a double-stranded DNA end and a short single-stranded DNA gap triggers robust activation of endogenous ATR and Chk1 mediated by DNA-PKcs.

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